NKX6-1 antibody

Principal name

NKX6-1 antibody

Alternative names for NKX6-1 antibody

NKX6A, Homeobox protein Nkx-6.1

SwissProt ID

O35762 (Rat), P78426 (Human), Q60554 (Mesau), Q99MA9 (Mouse)

Gene ID

4825 (NKX6-1)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Ms (Mouse), Rt (Rat), Ze (Zebrafish), African clawed frog, Eq (Equine), Por (Porcine), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of NKX6-1 antibody

NKX6-1 is the transcription factor which binds to specific A/T-rich D sequences in the promoter regions of a number of genes. NKX6-1 is involved in transcriptiol regulation in islet beta cells. Binds to the insulin promoter and is involved in regulation of the insulin gene. Together with NKX2-2 and IRX3, NKX6-1 acts to restrict the generation of motor neurons to the appropriate region of the neural tube. NKX6-1 belongs to the class II proteins of neurol progenitor factors, which are induced by SHH sigls.In the pancreas, NKX6.1 is required for the development of beta cells and is a potent bifunctiol transcription regulator that binds to AT-rich sequences within the promoter region of target genes Iype et al. (2004) [PubMed 15056733].[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-300 U66797.1 1-300 301-307 AC096766.3 119394-119400 c 308-676 U66797.1 308-676 677-849 U66798.1 7-179 850-1116 U66799.1 7-273

General readings

Donelan, W. et al., J. Biol. Chem. 285(16): 12181-12189 (2010)
Zhu, S. et al., Dig. Dis. Sci. 54(5): 996-1002 (2009)
Schisler, J.C. et al., Mol. Cell. Biol. 28(10): 3465-3476 (2008)
Yokoi, N. et al., Diabetes 55(8): 2379-2386 (2006)
Hori, Y. et al., PLoS Med. 2 (4): e103 (2005)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

NKX6-1 antibody

Immunohistochemistry: Nkx6.1 Antibody - IHC staining of Nkx6.1 in mouse intestine. Rabbit Purified Hu, Ms C
0.1 ml / €325.00
  OriGene Technologies, Inc.

NKX6-1 antibody

Western blot analysis of extracts from CoLo cells, using NKX61 Antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

NKX6-1 antibody

WB Suggested Anti-NKX6-1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: Human Small Intestine Rabbit IgG Purified Bov, Can, Eq, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

NKX6-1 (C-term) antibody

Western blot analysis in A549 cell line lysates (35ug/lane) using NKX6-1 antibody Cat.-No. AP52893PU-N (C-term). This demonstrates this antibody detected the NKX6-1 protein (arrow). Rabbit Ig Aff - Purified Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

NKX6-1 antibody

NKX6-1 monoclonal antibody (M01), clone 1B7 Western Blot analysis of NKX6-1 expression in HL-60 ( Cat # L014V1 ). Mouse IgG2a 1B7 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

NKX6-1 antibody

NKX6-1 monoclonal antibody (M02), clone 1A7 Western Blot analysis of NKX6-1 expression in C32 ( Cat # L002V1 ). Mouse IgG2a 1A7 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

NKX6-1 (N-term) antibody

Human Small Intestine; WB Suggested Anti-NKX6-1 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: Human Small Intestine; NKX6-1 antibody - N-terminal region (ARP32720_P050) in Human Small Intestine cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Can, Hu, Ms, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

NKX6-1 antibody

NKX6-1 Rabbit Aff - Purified Hu, Ms P
0.1 ml / €440.00
  Novus Biologicals Inc.

NKX6-1 antibody

NKX6-1 Rabbit Aff - Purified Hu, Ms P
0.1 ml / €390.00
  Novus Biologicals Inc.

NKX6-1 antibody

NKX6-1 Rabbit Aff - Purified Hu, Ms P
0.1 ml / €390.00
  Novus Biologicals Inc.

NKX6-1 antibody

NKX6-1 Rabbit Aff - Purified Hu, Ms P
0.1 ml / €390.00
  Novus Biologicals Inc.

NKX6-1 antibody

NKX6-1 Rabbit Aff - Purified Hu, Ms P
0.1 ml / €390.00
  Novus Biologicals Inc.

NKX6-1 antibody

NKX6-1 Rabbit Aff - Purified Hu, Ms P, WB
25 µl / €200.00
  Novus Biologicals Inc.

NKX6-1 antibody

NKX6-1 Rabbit Aff - Purified Hu, Ms ICC/IF, P, WB
0.1 ml / €440.00
  Novus Biologicals Inc.

NKX6-1 antibody

NKX6-1 Rabbit Aff - Purified Hu, Ms ICC/IF, P, WB
0.1 ml / €400.00
  Novus Biologicals Inc.

NKX6-1 antibody

NKX6-1 Rabbit Aff - Purified Hu, Ms ICC/IF, P, WB
0.1 ml / €400.00
  Novus Biologicals Inc.

NKX6-1 antibody

NKX6-1 Rabbit Aff - Purified Hu, Ms ICC/IF, P, WB
0.1 ml / €510.00
  Novus Biologicals Inc.

NKX6-1 antibody

NKX6-1 Rabbit Aff - Purified Hu, Ms ICC/IF, P, WB
0.1 ml / €400.00
  Novus Biologicals Inc.

NKX6-1 antibody

NKX6-1 Rabbit Aff - Purified Bov, Hu, Ms ICC/IF, P, WB
25 µl / €200.00
  Novus Biologicals Inc.

NKX6-1 antibody

Immunohistochemistry-Paraffin: Nkx6.1 Antibody [NBP1-82553] - Immunohistochemical staining of human pancreas shows distinct nuclear positivity in islet cells). Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

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