NLRP6 antibody

Principal name

NLRP6 antibody

Alternative names for NLRP6 antibody

NALP6, PYPAF5, NACHT, LRR and PYD domains-containing protein 6

SwissProt ID

P59044 (Human), Q63035 (Rat), Q91WS2 (Mouse)

Gene ID

171389 (NLRP6)

Available reactivities

Hu (Human), Rt (Rat), Ms (Mouse)

Available hosts

Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of NLRP6 antibody

LP6 / NLRP6 (CHT, LRR and PYD domains-containing protein 6) belongs to NLRP family of proteins - NLRP1, NLRP3, NLRC4 and NLRP6 - which functions as inte sensors of endogenous/exogenous stress or damage-associated molecular patterns (DAMPs). NLRPs are vital components of inflammasomes which are the cytoplasmic multi-protein complexes that coordite several functions during inflammation and homeostasis in various type of cells/tissues. NLRP6 is a newly characterized NLR protein which is highly expressed in the intestil epithelium as well as the granulocytes, and to a relatively lower levels on T-cells. LP6 acts as an arginine-vasopressin V2 receptor and has been suggested to contribute to AVP-mediated regulation of rel salt-water balance, glucose and lipid metabolism, apoptosis, and/or cell cycle. It implicates in the activation of CASP1 via ASC, promotion of NFkB activation and cAMP accumulation stimulation. LP6 has been shown to actively participate in inflammasome sigling and to play critical roles in defense against infection, auto-inflammation and tumorigenesis.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

NLRP6 (N-term) antibody

Western blot analysis of NALP6 in human heart tissue lysate with NALP6 antibody at 1 ?g/ml in (A) the absence and (B) the presence of blocking peptide. Rabbit Aff - Purified Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

NLRP6 antibody

Western Blot: NALP6 Antibody [TA337214] - WB detection of NALP6 protein (NACHT, LRR and PYD domains-containing protein 6) in (A) Jurkat cells lysate and (B) partial recombinant protein using NALP6 antibody at a concentration of 1 ug/ml for lysate and 0.1 Rabbit Purified Hu C, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

NLRP6 control peptide

NLRP6
50 µg / €160.00
  Acris Antibodies GmbH

NLRP6 antibody

NLRP6 Rabbit Hu, Rt E, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

NLRP6 overexpression lysate

NLRP6 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

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