Nociceptin antibody

Principal name

Nociceptin antibody

Alternative names for Nociceptin antibody

Pnoc

SwissProt ID

O62647 (Bovin), P55791 (Pig), Q13519 (Human), Q62923 (Rat), Q64387 (Mouse)

Gene ID

5368 (PNOC), 25516 (Pnoc)

Available reactivities

Hu (Human), Mky (Monkey), Rt (Rat), Ms (Mouse), Prim (Primate), GP (Guinea Pig), Bov (Bovine), Can (Canine), Eq (Equine), Por (Porcine), Ze (Zebrafish)

Available hosts

Guinea Pig, Rabbit, Mouse

Available applications

Frozen Sections (C), Enzyme Immunoassay (E), Flow Cytometry (F), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Western blot / Immunoblot (WB)

Background of Nociceptin antibody

Orphanin FQ (nociceptin, OFQ), a heptadecapeptide peptide, has been designated as an endogenous ligand for the ORL1 receptor. The amino acid sequence of OFQ has homology with other opioid peptides, especially the prodynorphin fragment dynorphin A, suggesting a close evolutionary relationship between the precursors. A diffuse distribution throughout the brain is seen with binding studies and in situ hybridization suggesting an extensive role for OFQ in a multitude of CNS functions. Immunocytochemical localizations in rat spinal cord have demonstrated OFQ abundance in superficial dorsal horn, lateral spinal nucleus and the region dorsal to the central canal. OFQ immunoreactivity was not affected by dorsal rhizotomy, indicating that in spinal cord the peptide is produced by central rather than primary afferent neurons. The localization is supported by its function in processing of nociceptive signals.

General readings

General / background references:Riedl M et al. Orphanin FQ/nociceptin-immunoreactive nerve fibers parallel those containing endogenous opioids in rat spinal cord. Neuroreport 7:1369-72 (1996). PubMed PMID: 8856677
Meunier JC et al. Isolation and structure of the endogenous agonist of opioid receptor-like ORL1 receptor. Nature 377:532-5 (1995). PubMed PMID: 7566152
Reinscheid RK et al. Orphanin FQ: a neuropeptide that activates an opioidlike G protein-coupled receptor. Science 270:792-4 (1995). PubMed PMID: 7481766

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Nociceptin antibody

Predicted band size: 20 kDa . Positive control: Human liver cancer tissue lysate. Recommended dilution: 1/1000-5000 Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Nociceptin antibody

WB Suggested Anti-PNOC Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: HepG2 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

Nociceptin (Center) antibody

Formalin-fixed and paraffin-embedded human brain tissue reacted with Nociceptin Antibody Cat.-No AP53369PU-N, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Rabbit Ig Aff - Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Nociceptin antibody

Nociceptin Mouse IgG2a 4F6 Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Nociceptin antibody

Nociceptin Rabbit GP, Rt C, E
0.1 ml / €390.00
  Abnova Taiwan Corp.

Nociceptin antibody

Human HepG2; WB Suggested Anti-PNOC Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: HepG2 cell lysate; PNOC antibody - middle region (ARP56692_P050) in Human HepG2 cells using Western Blot Rabbit Aff - Purified Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

Nociceptin antibody

Nociceptin Guinea Pig Serum Hu, Mky, Rt C
50 µl / €200.00
  Neuromics Antibodies

Nociceptin antibody

Nociceptin Guinea Pig Serum Hu, Mky, Rt C
0.15 ml / €350.00
  Neuromics Antibodies

Nociceptin antibody

Nociceptin Purified
20 µg / €150.00
  Neuromics Antibodies

Nociceptin antibody

Nociceptin Rabbit Serum Hu, Mky, Rt C
50 µl / €190.00
  Neuromics Antibodies

Nociceptin antibody

Nociceptin Rabbit Serum Hu, Mky, Rt C
0.15 ml / €350.00
  Neuromics Antibodies

Nociceptin antibody

Immunohistochemistry: Nociceptin Antibody [NB100-1619] -This orphanin FQ robustly stains nerve fibers in brain and spinal cord. Animals were treated with colchicines to visualize orphanin FQ-expressing cell bodies. Staining was blocked by preabsorption with the cognate peptide. Rabbit IgG Serum Hu, Mky, Ms, Rt C, F, ICC/IF, P, WB
50 µl / €310.00
  Novus Biologicals Inc.

Nociceptin antibody

Immunohistochemistry: Nociceptin Antibody [NB100-1659] - Immunohistochemistry: This orphanin FQ robustly stains nerve fibers in brain and spinal cord. Animals were treated with colchicines to visualize orphanin FQ-expressing cell bodies. Staining was blocked by preabsorption with the cognate peptide. Guinea Pig IgG Serum Hu, Mky, Ms, Rt E, P, WB
50 µl / €310.00
  Novus Biologicals Inc.

Nociceptin antibody

Western Blot: Nociceptin Antibody [NBP1-59307] - This Anti-PNOC antibody was used in Western Blot of HepG2     tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu, Ms, Rt WB
50 µg / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Nociceptin (20-176, His-tag)

Nociceptin Human Purified > 90 % by SDS - PAGE E. coli
0.5 mg / €730.00
  Acris Antibodies GmbH

Nociceptin (20-176, His-tag)

Nociceptin Human Purified > 90 % by SDS - PAGE E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

Nociceptin

Nociceptin Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

Nociceptin

Nociceptin Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Nociceptin

Nociceptin Human
10 µg / €380.00
  Abnova Taiwan Corp.

Nociceptin

Nociceptin Human
25 µg / €510.00
  Abnova Taiwan Corp.

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