Noggin antibody

Principal name

Noggin antibody

Alternative names for Noggin antibody

NOG

SwissProt ID

P97466 (Mouse), Q13253 (Human), Q62809 (Rat)

Gene ID

9241 (NOG), 18121 (Nog)

Available reactivities

Ms (Mouse), Hu (Human), Rt (Rat), Can (Canine), Bov (Bovine), Por (Porcine), Sh (Sheep)

Available hosts

Goat, Mouse, Rabbit

Available applications

Frozen Sections (C), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Paraffin Sections (P), Immunoprecipitation (IP)

Background of Noggin antibody

The secreted polypeptide, encoded by this gene, binds and ictivates members of the transforming growth factor-beta (TGF-beta) superfamily sigling proteins,such as bone morphogenetic protein-4 (BMP4).By diffusing through extracellular matrices more efficiently than members of the TGF-beta superfamily,this protein may have a principal role in creating morphogenic gradients.The protein appears to have pleiotropic effect,both early in development as well as in later stages.It was origilly isolated from Xenopus based on its ability to restore normal dorsal-ventral body axis in embryos that had been artificially ventralized by UV treatment.The results of the mouse knockout of the ortholog suggest that it is involved in numerous developmental processes,such as neural tube fusion and joint formation. Recently,several domint human NOG mutations in unrelated families with proximal symphalangism (SYM1) and multiple synostoses syndrome (SYNS1) were identified;both SYM1 and SYNS1 have multiple joint fusion as their principal feature,and map to the same region (17q22) as this gene.All of these mutations altered evolutiorily conserved amino acid residues.The amino acid sequence of this human gene is highly homologous to that of Xenopus,rat and mouse.[provided by RefSeq,Jul 2008]

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Noggin antibody

  Noggin (Noggin) mouse monoclonal antibody, clone OTI4C12 (formerly 4C12)  
Immunohistochemical staining of paraffin-embedded Human Ovary tissue within the normal limits using anti-Nog mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500028) Mouse IgG2b OTI4C12 Purified Can, Hu ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Noggin antibody

  Noggin (Noggin) mouse monoclonal antibody, clone OTI1H8 (formerly 1H8)  
Immunohistochemical staining of paraffin-embedded Human Ovary tissue within the normal limits using anti-Nog mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500029) Mouse IgG2b OTI1H8 Purified Hu ICC/IF, P, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

Noggin antibody

  anti-Noggin (Noggin) mouse monoclonal antibody, clone OTI1C1 (formerly 1C1)  
Immunohistochemical staining of paraffin-embedded Carcinoma of lung using anti-Nog (TA500116) mouse monoclonal antibody (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min). Mouse IgG2b OTI1C1 Purified Hu ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Noggin antibody

  Rabbit Polyclonal Noggin Antibody  
Western Blot: Noggin Antibody [TA336497] 20ug of human hippocampus tissue lysate (lanes 2 and 4) with Noggin polyclonal at 1:1000 dilution followed by secondary at 1:5000 dilution MW marker Lane 1 peptide absorption control lane 3. Rabbit Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Noggin antibody

  Rabbit Polyclonal Noggin Antibody  
Western Blot: Noggin Antibody [TA336514] - Western blot detection of Noggin in 20 ug of human hippocampus tissue lysate (lanes 2 and 4) with Noggin polyclonal at 1:1000 dilution followed by AP-conjugated secondary at 1:5000 dilution. MW marker lane 1. Pep Rabbit Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Noggin antibody

  Rabbit Polyclonal Anti-NOG Antibody - middle region  
WB Suggested Anti-NOG Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: ACHN cell lysate Rabbit IgG Purified Bov, Can, Hu, Ms, Por, Rt, Sh WB
50 µg / €325.00
  OriGene Technologies, Inc.

Noggin antibody

  Mouse Monoclonal Noggin Antibody  
Western blot detection of Noggin in CHO-K1 cell lysates over-expressing Noggin-PDGFR transmembrane domain fused protein using Noggin mouse mAb (1:1000 diluted).Predicted band size:26KDa.Observed band size:37KDa. Mouse IgG3 1D2-G8-G1 Purified ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Noggin antibody

Brain, cerebellum: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

Noggin antibody

Noggin staining of Cardiac Tissue of 11 d.p.c. Mouse Embryos. Tissue was stained with goat HRP-DAB  (brown) and  counterstained with Hematoxylin (blue). Goat Aff - Purified Ms C, E, ICC/IF, WB
0.1 mg / €450.00
  Neuromics Antibodies

CRISPR

Catalog No. Species Donor Vector  

NOG - human gene knockout kit via CRISPR

NOG - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

NOG - human gene knockout kit via CRISPR

NOG - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Nog - mouse gene knockout kit via CRISPR

Nog - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Nog - mouse gene knockout kit via CRISPR

Nog - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Nog - mouse gene knockout kit via CRISPR

Nog - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Nog - mouse gene knockout kit via CRISPR

Nog - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Noggin

  Purified recombinant protein of Human noggin (NOG).  
Noggin Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €399.00

Special Price: 20 µg / €239.00

  OriGene Technologies, Inc.

Noggin

  Purified recombinant protein of Mouse noggin (Nog).  
Noggin Mouse > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
E. coli

Regular Price: 20 µg / €199.00

Special Price: 20 µg / €139.00

  OriGene Technologies, Inc.

Noggin (Fc Chimera)

Noggin Human Purified > 90 %
50 µg / €400.00
  Neuromics Antibodies

Lysates

Catalog No.    

NOG overexpression lysate

NOG overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, NOG (Myc-DDK tagged) - Human noggin (NOG) , 200 uL, >10^7 TU/mL

Lenti ORF particles, NOG (Myc-DDK tagged) - Human noggin (NOG) , 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

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