NOXA1 antibody

Principal name

NOXA1 antibody

Alternative names for NOXA1 antibody

P51NOX, NADPH oxidase activator, P67phox-like factor, p51-nox, NCF2-like protein, Antigen NY-CO-31

SwissProt ID

A7E3N7 (Rat), Q86UR1 (Human), Q8CJ00 (Mouse)

Gene ID

10811 (NOXA1), 241275 (Noxa1), 311793

Available reactivities

Hu (Human)

Available hosts

Mouse, Rabbit

Available applications

ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Immunoprecipitation (IP)

Background of NOXA1 antibody

NOXA1 (NADPH oxidase activator 1), also called NOX ACTIVATOR 1 or p51-NOX, is an enzyme that in humans is encoded by the NOXA1 gene. Hartz (2007) mapped the NOXA1 gene to chromosome 9q34.3 based on an alignment of the NOXA1 sequence with the genomic sequence (build 36.1). Banfi et al. (2003) mapped the mouse Noxa1 gene to chromosome 2. Using yeast 2-hybrid assays, Takeya et al. (2003) showed that human p51-NOX interacted with constitutively active forms of RAC1 and RAC2. In vitro binding assays revealed that p51-NOX bound GTP-bound RAC1, but not GDP-bound RAC1. p51-NOX also bound p47-PHOX (NCF1) and p41-NOX (NOXO1), and trp436 within the SH3 domain of p51-NOX was required for these interactions. Human cell lines or COS-7 cells cotransfected with p51-NOX and p41-NOX and either gp91-PHOX (CYBB) or NOX1 produced superoxide. Cells individually transfected with NOX1, p41-NOX, or p51-NOX and cells transfected with only p41-NOX and p51-NOX showed no superoxide production.

General readings

Niu, X.L. et al., Circulation 121(4): 549-559 (2010)
Pacquelet, S. et al., J. Biol. Chem. 283(36): 24649-24658 (2008)
Honjo, T. et al., Endothelium 15(3): 137-141 (2008)
Kim, J.S. et al., J. Biol. Chem. 282(48): 34787-34800 (2007)
Valente, A.J. et al., Free Radic. Biol. Med. 43(3): 384-396 (2007)
Cheng, G. et al., J. Biol. Chem. 281(26): 17718-17726 (2006)

19 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

NOXA1 (C-term) antibody

Western blot analysis of NOXA1 (arrow) in MDA-MB435 cell line lysates (35ug/lane) using NOXA1 antibody Cat.-No. AP52915PU-N (C-term). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

NOXA1 - human gene knockout kit via CRISPR

NOXA1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

NOXA1 - human gene knockout kit via CRISPR

NOXA1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

NOXA1 - human gene knockout kit via CRISPR

NOXA1 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

NOXA1 - human gene knockout kit via CRISPR

NOXA1 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Noxa1 - mouse gene knockout kit via CRISPR

Noxa1 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Noxa1 - mouse gene knockout kit via CRISPR

Noxa1 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Noxa1 - mouse gene knockout kit via CRISPR

Noxa1 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Noxa1 - mouse gene knockout kit via CRISPR

Noxa1 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

NOXA1

  Recombinant protein of human NADPH oxidase activator 1 (NOXA1)  
NOXA1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

Lysates

Catalog No.    

NOXA1 overexpression lysate

NOXA1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, NOXA1 (mGFP-tagged) - Human NADPH oxidase activator 1 (NOXA1), 200 uL, >10^7 TU/mL

Lenti ORF particles, NOXA1 (mGFP-tagged) - Human NADPH oxidase activator 1 (NOXA1), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, NOXA1 (Myc-DDK tagged) - Human NADPH oxidase activator 1 (NOXA1) , 200 uL, >10^7 TU/mL

Lenti ORF particles, NOXA1 (Myc-DDK tagged) - Human NADPH oxidase activator 1 (NOXA1) , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Noxa1 (GFP-tagged) - Mouse NADPH oxidase activator 1 (Noxa1), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, Noxa1 (GFP-tagged) - Mouse NADPH oxidase activator 1 (Noxa1), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,040.00
  OriGene Technologies, Inc.

Lenti ORF particles, Noxa1 (GFP-tagged) - Mouse NADPH oxidase activator 1 (Noxa1), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, Noxa1 (GFP-tagged) - Mouse NADPH oxidase activator 1 (Noxa1), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,030.00
  OriGene Technologies, Inc.

Lenti ORF particles, Noxa1 (Myc-DDK-tagged) - Mouse NADPH oxidase activator 1 (Noxa1), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, Noxa1 (Myc-DDK-tagged) - Mouse NADPH oxidase activator 1 (Noxa1), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €930.00
  OriGene Technologies, Inc.

Lenti ORF particles, Noxa1 (Myc-DDK-tagged) - Mouse NADPH oxidase activator 1 (Noxa1), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, Noxa1 (Myc-DDK-tagged) - Mouse NADPH oxidase activator 1 (Noxa1), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €920.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Noxa1 (GFP-tagged ORF) - Rat NADPH oxidase activator 1 (Noxa1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Noxa1 (GFP-tagged ORF) - Rat NADPH oxidase activator 1 (Noxa1), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, Noxa1 (Myc-DDK-tagged ORF) - Rat NADPH oxidase activator 1 (Noxa1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Noxa1 (Myc-DDK-tagged ORF) - Rat NADPH oxidase activator 1 (Noxa1), 200 uL, >10^7 TU/mL  
200 µl / €936.00
  OriGene Technologies, Inc.

19 Item(s)

per page
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