NOXA1 antibody

Principal name

NOXA1 antibody

Alternative names for NOXA1 antibody

P51NOX, NADPH oxidase activator, P67phox-like factor, p51-nox, NCF2-like protein, Antigen NY-CO-31

SwissProt ID

A7E3N7 (Rat), Q86UR1 (Human), Q8CJ00 (Mouse)

Gene ID

10811 (NOXA1)

Available reactivities

Hu (Human)

Available hosts

Mouse, Rabbit

Available applications

ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunoprecipitation (IP)

Background of NOXA1 antibody

NOXA1 (NADPH oxidase activator 1), also called NOX ACTIVATOR 1 or p51-NOX, is an enzyme that in humans is encoded by the NOXA1 gene. Hartz (2007) mapped the NOXA1 gene to chromosome 9q34.3 based on an alignment of the NOXA1 sequence with the genomic sequence (build 36.1). Banfi et al. (2003) mapped the mouse Noxa1 gene to chromosome 2. Using yeast 2-hybrid assays, Takeya et al. (2003) showed that human p51-NOX interacted with constitutively active forms of RAC1 and RAC2. In vitro binding assays revealed that p51-NOX bound GTP-bound RAC1, but not GDP-bound RAC1. p51-NOX also bound p47-PHOX (NCF1) and p41-NOX (NOXO1), and trp436 within the SH3 domain of p51-NOX was required for these interactions. Human cell lines or COS-7 cells cotransfected with p51-NOX and p41-NOX and either gp91-PHOX (CYBB) or NOX1 produced superoxide. Cells individually transfected with NOX1, p41-NOX, or p51-NOX and cells transfected with only p41-NOX and p51-NOX showed no superoxide production.

General readings

Niu, X.L. et al., Circulation 121(4): 549-559 (2010)
Pacquelet, S. et al., J. Biol. Chem. 283(36): 24649-24658 (2008)
Honjo, T. et al., Endothelium 15(3): 137-141 (2008)
Kim, J.S. et al., J. Biol. Chem. 282(48): 34787-34800 (2007)
Valente, A.J. et al., Free Radic. Biol. Med. 43(3): 384-396 (2007)
Cheng, G. et al., J. Biol. Chem. 281(26): 17718-17726 (2006)

12 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

NOXA1 (C-term) antibody

Western blot analysis of NOXA1 (arrow) in MDA-MB435 cell line lysates (35ug/lane) using NOXA1 antibody Cat.-No. AP52915PU-N (C-term). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

NOXA1 antibody

Western Blot analysis of NOXA1 expression in transfected 293T cell line (H00010811-T02) by NOXA1 MaxPab polyclonal antibody.

Lane 1: NOXA1 transfected lysate(53.13 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

NOXA1 antibody

NOXA1 Rabbit Serum Hu E(detection), IP, WB
0.1 ml / €380.00
  Abnova Taiwan Corp.

NOXA1 antibody

NOXA1 Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

NOXA1 antibody

NOXA1 Rabbit IgG Aff - Purified Hu WB
0.1 mg / €290.00
  Boster Immunoleader

NOXA1 antibody

Immunohistochemistry-Paraffin: NOXA1 Antibody [NBP1-92197] Immunohistochemical staining of human kidney shows strong cytoplasmic and membranous positivity in cells in tubules. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

NOXA1

NOXA1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

NOXA1

NOXA1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

NOXA1

NOXA1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Antibody Pairs

Catalog No.    

NOXA1 (Human) IP-WB Antibody Pair

NOXA1 (Human) IP-WB Antibody Pair  
1 set / €710.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

NOXA1 293T Cell Transient Overexpression Lysate(Denatured)

NOXA1 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

NOXA1 overexpression lysate

NOXA1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

12 Item(s)

per page
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