NP antibody

Principal name

NP antibody

Alternative names for NP antibody

PNP, PNP1, Inosine Phosphorylase, Purine Nucleoside Phosphorylase

SwissProt ID

P00491 (Human), P23492 (Mouse), P55859 (Bovin), P85973 (Rat)

Gene ID

4860 (PNP)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Ze (Zebrafish)

Available hosts

Rabbit, Mouse, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Dot blot (Dot), Immunodiffusion (ID), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Radioimmunoassay (R), Paraffin Sections (P)

Background of NP antibody

Defects in NP are the cause of nucleoside phosphorylase deficiency (NP deficiency). It leads to a severe T-cell immunodeficiency with neurologic disorder in children. The specific function of NP is not yet known.This gene encodes an enzyme which reversibly catalyzes the phosphorolysis of purine nucleosides. The enzyme is trimeric, containing three identical subunits. Mutations which result in nucleoside phosphorylase deficiency result in defective T-cell (cell-mediated) immunity but can also affect B-cell immunity and antibody responses. Neurologic disorders may also be apparent in patients with immune defects. A known polymorphism at aa position 51 that does not affect enzyme activity has been described. A pseudogene has been identified on chromosome 2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

Dautant A., et al. (2010) J Biol Chem. 285(38):29502-10.
Balakrishnan K., et al. (2010) Blood. 116(6):886-92.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

NP antibody

Hum. Adult Placenta; Host: Rabbit .  Target Name: PNP .  Sample Tissue: Human Adult Placenta . Antibody Dilution: 1.0ug/ml.; NP antibody - middle region (ARP48474_P050) in Hum. Adult Placenta cells using Western Blot Rabbit Aff - Purified Bov, Hu, Ms, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

NP (142-153) antibody

AP32724PU-N PNP Antibody staining of Human Liver lysate  at 0.1µg/ml (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Hu WB
0.1 mg / €340.00
  Acris Antibodies GmbH

NP antibody

Western blot analysis of extracts of various cell lines, using PNP antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

NP antibody

NP Rabbit IgG Azide Free Bov Dot, E, ICC/IF, ID, IP, R, WB
10 mg / €230.00
  Acris Antibodies GmbH

NP antibody

NP Rabbit IgG Biotin Bov Dot, E, ICC/IF, ID, IP, R, WB
1 ml / €340.00
  Acris Antibodies GmbH

NP antibody

NP Rabbit IgG Aff - Purified Bov Dot, E, ICC/IF, ID, IP, R, WB
1 mg / €430.00
  Acris Antibodies GmbH

NP antibody

NP polyclonal antibody (A01), Lot # 051017JC01 Western Blot analysis of NP expression in Jurkat ( Cat # L017V1 ). Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

NP antibody

NP Mouse IgG2a 6E5 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

NP antibody

Western Blot: nucleoside phosphorylase Antibody [NBP1-54353] - This Anti-NP antibody was used in Western Blot of THP-1     tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu WB
50 µg / €440.00
  Novus Biologicals Inc.

NP antibody

Immunohistochemistry-Paraffin: Nucleoside phosphorylase Antibody [NBP1-82541] - Immunohistochemical staining of human kidney shows strong cytoplasmic and nuclear positivity in cells of tubules. Rabbit IgG Aff - Purified Hu, Ms, Rt P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

NP

NP Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

NP (1-289, His-tag)

NP Human Purified > 90 % E. coli
0.5 mg / €750.00
  Acris Antibodies GmbH

NP (1-289, His-tag)

NP Human Purified > 90 % E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

NP

NP Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

NP

NP Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

NP

NP Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

NP

NP Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

NP

NP Human Purified
0.1 mg / €380.00
  Novus Biologicals Inc.

NP

NP Human Purified
0.5 mg / €870.00
  Novus Biologicals Inc.

19 Item(s)

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