NPAS3 / MOP6 antibody

Principal name

NPAS3 / MOP6 antibody

Alternative names for NPAS3 / MOP6 antibody

Neuronal PAS3, Neuronal PAS domain-containing protein 3, Member of PAS protein 6, Basic-helix-loop-helix-PAS protein MOP6

SwissProt ID

Q8IXF0 (Human), Q9QZQ0 (Mouse)

Gene ID

64067 (NPAS3)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Gt (Goat), Por (Porcine), Rb (Rabbit), Ze (Zebrafish)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Frozen Sections (C), Enzyme Immunoassay (E)

Background of NPAS3 / MOP6 antibody

Neuronal PAS domain protein 3 (NPAS3) is a brain-enriched basic helix-loop-helix PAS domain transcription factor and is broadly expressed in the developing neuroepithelium and has recently been found to be disrupted by genetic translocation in a family affected with schizophrenia. It was recently shown to be involved in the regulation of FGF signaling in the dentate gyrus by controlling the expression of the FGF receptor subtype 1 and in turn neurogenesis emanating from this region. NPAS3-null mice were growth-retarded and displayed brain defects that included reduced size of the anterior hippocampus, hypoplasia of the corpus callosum, and enlargement of the ventricles, as well as several behavioral abnormalities. Furthermore, these NPAS3- null mice also exhibited disruptions in several neurosignaling pathways involving glutamate, dopamine, and serotonin. These results demonstrate the essential role played by NPAS3 during structural and functional brain development. At least three isoforms of NPAS3 are known to exist.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

NPAS3 / MOP6 (N-term) antibody

  Rabbit Polyclonal NPAS3 Antibody  
Western blot analysis of NPAS3 in SK-N-SH cell lysate with NPAS3 antibody at (A) 0.5, (B) 1 and (C) 2 ug/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

NPAS3 / MOP6 (Center) antibody

  Rabbit Polyclonal NPAS3 Antibody  
Western blot analysis of NPAS3 in rat brain tissue lysate with NPAS3 antibody at (A) 0.5, (B) 1 and (C) 2 ug/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

NPAS3 / MOP6 antibody

  Rabbit Polyclonal Anti-NPAS3 Antibody  
Host: Rabbit; Target Name: NPAS3; Sample Tissue: THP-1 Whole Cell lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Bov, Can, Eq, GP, Gt, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

NPAS3 / MOP6 antibody

Testis: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit Aff - Purified Hu, Ms, Rt P, WB
50 µg / €470.00
  Acris Antibodies GmbH

NPAS3 / MOP6 antibody

Figure 1. Formalin-Fixed Paraffin-Embedded (FFPE) on Brain, cortex. Rabbit Purified Hu, Ms, Rt P, WB
50 µg / €470.00
  Acris Antibodies GmbH

NPAS3 / MOP6 antibody

NPAS3 / MOP6 Rabbit Serum Ms C, E, WB
0.2 ml / €400.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

NPAS3 - human gene knockout kit via CRISPR

NPAS3 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

NPAS3 - human gene knockout kit via CRISPR

NPAS3 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

NPAS3 - human gene knockout kit via CRISPR

NPAS3 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

NPAS3 - human gene knockout kit via CRISPR

NPAS3 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

NPAS3 overexpression lysate

NPAS3 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, NPAS3 (mGFP-tagged)-Human neuronal PAS domain protein 3 (NPAS3), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, NPAS3 (mGFP-tagged)-Human neuronal PAS domain protein 3 (NPAS3), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,930.00
  OriGene Technologies, Inc.

Lenti ORF particles, NPAS3 (mGFP-tagged)-Human neuronal PAS domain protein 3 (NPAS3), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, NPAS3 (mGFP-tagged)-Human neuronal PAS domain protein 3 (NPAS3), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,890.00
  OriGene Technologies, Inc.

Lenti ORF particles, NPAS3 (mGFP-tagged)-Human neuronal PAS domain protein 3 (NPAS3), transcript variant 3, 200 uL, >10^7 TU/mL

Lenti ORF particles, NPAS3 (mGFP-tagged)-Human neuronal PAS domain protein 3 (NPAS3), transcript variant 3, 200 uL, >10^7 TU/mL  
200 µl / €1,920.00
  OriGene Technologies, Inc.

Lenti ORF particles, NPAS3 (Myc-DDK-tagged)-Human neuronal PAS domain protein 3 (NPAS3), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, NPAS3 (Myc-DDK-tagged)-Human neuronal PAS domain protein 3 (NPAS3), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,740.00
  OriGene Technologies, Inc.

Lenti ORF particles, NPAS3 (Myc-DDK-tagged)-Human neuronal PAS domain protein 3 (NPAS3), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, NPAS3 (Myc-DDK-tagged)-Human neuronal PAS domain protein 3 (NPAS3), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,700.00
  OriGene Technologies, Inc.

Lenti ORF particles, NPAS3 (Myc-DDK-tagged)-Human neuronal PAS domain protein 3 (NPAS3), transcript variant 3, 200 uL, >10^7 TU/mL

Lenti ORF particles, NPAS3 (Myc-DDK-tagged)-Human neuronal PAS domain protein 3 (NPAS3), transcript variant 3, 200 uL, >10^7 TU/mL  
200 µl / €1,730.00
  OriGene Technologies, Inc.

17 Item(s)

per page
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