NPY receptor 1 / NPY1R antibody

Principal name

NPY receptor 1 / NPY1R antibody

Alternative names for NPY receptor 1 / NPY1R antibody

NPYR, NPYY1, Neuropeptide Y receptor 1

SwissProt ID

O02813 (Canfa), O02835 (Pig), P21555 (Rat), P25929 (Human), P34992 (Xenla), Q04573 (Mouse), Q1RMU8 (Bovin), Q28602 (Sheep), Q9WVD0 (Cavpo)

Gene ID

4886 (NPY1R), 18166 (Npy1r), 29358

Available reactivities

Frog, GP (Guinea Pig), Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Por (Porcine), Rb (Rabbit), Bt (Bat), Eq (Equine), Hst (Hamster), Mky (Monkey), Sh (Sheep), Xen (Xenopus), L (Lizard), Bear

Available hosts

Rabbit, Sheep, Mouse

Available applications

Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), ELISA (detection) (E(detection))

Background of NPY receptor 1 / NPY1R antibody

Neuropeptide Y Receptor Y1 (NPY1R) is a G-Protein Coupled Receptor containing characteristic 7 transmembrane spanning domains of the Neuropeptide Y (NPY) receptor family that includes NPY2R and NPY5R; it is located at human chromosome 4q31.3-32 (1). It is activated by the binding of NPY, a neurotransmitter in the central and peripheral nervous system (2). Activation of NPY1R is generally associated with reduction of cAMP accumulation, increase of intracellular free calcium concentration and modulation of MAPK pathway via several signaling molecules, including the protein kinase C (PKC) (3). The presence of NPY1R is important in the migration of endothelial cells and its activation also stimulates cell proliferation (3, 4). NPY1R is therefore a potential new molecular target in cancer treatment.
NPY is suggested to play an important role in tumor biology based on the high density of NPY receptors in many cancers (5). Among the five NPY receptors (NPY1R-5R), NPY1R is highly expressed in and its activation is important in the proliferation of cells in cortical tumors, prostrate cancer, Ewing sarcoma family of tumors, synovial sarcomas and on blood vessels in many other sarcomas (5, 6). NPY1R is also expressed in heart, colon, kidney, brain, adrenal gland and placenta. NPY1R is approximately a 56kDa protein (384 amino acids), the unexpected larger size of the mature protein is probably due to post-translational modifications including several glycosylation sites near the N-terminal end of the protein.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

NPY receptor 1 / NPY1R (2nd Extracell. Dom.) antibody

  Rabbit Polyclonal Anti-NPY1R Antibody (Extracellular Domain)  
Human, Kidney: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit Aff - Purified Bear, Bov, Can, Elephant, Eq, GP, Hst, Hu, Mky, Ms, Por, Rb, Rt, Sh P
50 µg / €400.00
  OriGene Technologies, Inc.

NPY receptor 1 / NPY1R antibody

  Rabbit polyclonal anti-NPY1R antibody  
Western blot analysis of extracts from NIH-3T3 cells, using NPY1R antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

NPY receptor 1 / NPY1R antibody

  Anti-NPY1R rabbit polyclonal antibody  
Predicted band size: 44kDa. Positive control: Human leiomyosarcoma tissue lysate. Recommended dilution: 1/500-2000. (Gel: 10%SDS-PAGE Lysate: 60 ug Primary antibody: 1/400 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/8000 dilution Exposure time: 2 minutes) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

NPY receptor 1 / NPY1R antibody

  Anti-NPY1R Rabbit Polyclonal Antibody  
Predicted band size: 44 kDa . Positive control: Human fetal brain tissue lysate. Recommended dilution: 1/500-2000. (Gel: 10%SDS-PAGE Lysate: 60 ug per lane Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 2 minutes) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

NPY receptor 1 / NPY1R antibody

  Rabbit anti-NPY1R Polyclonal Antibody  
Western blot analysis of extracts of mouse fetal brain cell line, using NPY1R antibody. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

NPY receptor 1 / NPY1R antibody

  Rabbit Polyclonal Anti-Neuropeptide Y1 Receptor  
Western blot analysis of Jurkat (lanes 1 and 4), K562 (lanes 2 and 5), and RBL (lanes 3 and 6) cell lysates and rat brain lysates (lanes 7 and 8): 1, 2, 3, 7. Anti-Neuropeptide Y1 Receptor antibody, (1:200). 4, 5, 6, 8. Anti-Neuropeptide Y1 Receptor antibody preincubated with the control peptide antigen. Rabbit Purified Hu, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

NPY receptor 1 / NPY1R (3rd cytoplasm. dom.) antibody

  Rabbit Polyclonal Anti-NPY1R Antibody (Cytoplasmic Domain)  
Anti-NPY1R antibody IHC of human brain. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Bov, Bt, Can, Eq, GP, Hst, Hu, L, Mky, Ms, Por, Rb, Rt, Sh, Xen P
50 µg / €400.00
  OriGene Technologies, Inc.

NPY receptor 1 / NPY1R antibody

  Rabbit Polyclonal Anti-NPY1R Antibody  
NPY receptor 1 / NPY1R Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt, Sh P
50 µg / €325.00
  OriGene Technologies, Inc.

NPY receptor 1 / NPY1R antibody

Western blot (WB) analysis of NPY1-R antibody (Cat.-No AP01221PU-N) in extracts from NIH-3T3 cells. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

NPY receptor 1 / NPY1R (C-term) antibody

NPY1R Polyclonal Antibody Rabbit IgG Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €340.00
  Acris Antibodies GmbH

NPY receptor 1 / NPY1R (365-378) antibody

NPY receptor 1 / NPY1R Sheep Purified Hu, Rt E, P, WB
1 ml / €330.00
  Acris Antibodies GmbH

NPY receptor 1 / NPY1R antibody

Western blot analysis of extracts from NIH-3T3 cells, using NPY1R Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
50 µg / €230.00
  Assay Biotech

NPY receptor 1 / NPY1R antibody

Western blot analysis of extracts from NIH-3T3 cells, using NPY1R Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €330.00
  Assay Biotech

NPY receptor 1 / NPY1R (356-382) antibody

Staining with Neuropeptide Y Y1 Receptor Antibody (24506) Rabbit Serum Frog, GP, Hu, Ms, Rt C, ICC/IF
0.1 ml / €490.00
  ImmunoStar Inc.

NPY receptor 1 / NPY1R antibody

NPY Y1 immunofluorescent of Rat DRG cells  visualised by FITC. Dilution 1:500   Rabbit Aff - Purified Rt C, ICC/IF, P, WB
0.1 ml / €490.00
  Neuromics Antibodies

CRISPR

Catalog No. Species Donor Vector  

Npy1r - mouse gene knockout kit via CRISPR

Npy1r - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Npy1r - mouse gene knockout kit via CRISPR

Npy1r - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Npy1r - mouse gene knockout kit via CRISPR

Npy1r - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Npy1r - mouse gene knockout kit via CRISPR

Npy1r - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

NPY1R overexpression lysate

NPY1R overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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