NPY receptor 4 / NPY4R antibody

Principal name

NPY receptor 4 / NPY4R antibody

Alternative names for NPY receptor 4 / NPY4R antibody

NPY4-R, PPYR1, Pancreatic polypeptide receptor 1, Neuropeptide Y receptor 4

SwissProt ID

P50391 (Human), Q61041 (Mouse), Q63447 (Rat)

Gene ID

100996758 (CH17-360D5.1), 29471 (Ppyr1), 5540 (PPYR1)

Available reactivities

Hu (Human), Bt (Bat), Bov (Bovine), Eq (Equine), Por (Porcine), Rb (Rabbit), Bear, Can (Canine), Mky (Monkey), Gorilla, Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E)

Background of NPY receptor 4 / NPY4R antibody

Neuropeptide Y (NPY) is a 36 amino acid peptide neurotransmitter in the central (CNS) and peripheral nervous systems. It belongs to the NPY family, along with peptide YY (PYY) and pancreatic polypeptide (PP). NPY is involved in the regulation of a broad range of homeostatic functions such as eating behavior, hypertension, and reproduction. NPY exerts its effects via five receptor subtypes known as the neuropeptide Y receptors (NPYR): Y1 (NPY1R), Y2 (NPY2R), Y4 (NPY4R), Y5 (NPY5R), and Y6 (NPY6R). Four of these (Y1, Y2, Y4, and Y5) are expressed in humans. The NPY receptors belong to the G protein-coupled receptor superfamily whose members share a common structure of seven putative transmembrane domains, an extracellular amino terminus, and a cytoplasmic carboxyl terminus. Activation of these receptors by NPY produces effects on [Ca2+]i, adenylate cyclase, and a number of ion channels.Based on their high frequency and density in steroid hormone-producing tumors, the NPYRs might be of potential use in tumor magement. NPY4R preferentially binds PP, while NPY1R, NPY2R, and NPY5R bind both NPY and PP. NPY1R, NPY2R, and NPY5R share a low degree of identity (27–31% overall). NPY4R is more similar to NPY1R, displaying an overall identity of 43–53%. Human NPY4R (also med pancreatic polypeptide receptor 1) mR is highly expressed in the small and large intestines and the prostate. Tissue distribution studies in human and mouse suggest potential roles for NPY4R in the gastrointestil tract, heart, and prostate, as well as in neural and endocrine sigling. Only low levels of NPY4R expression in various areas of brain were displayed.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

NPY receptor 4 / NPY4R (C-term) antibody

  PPYR1 Rabbit Polyclonal (C-Terminus) Antibody  
Anti-PPYR1 antibody IHC of human brain. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Bear, Bov, Bt, Eq, Hu, Por, Rb P
50 µg / €400.00
  OriGene Technologies, Inc.

NPY receptor 4 / NPY4R (2nd extracell. dom.) antibody

  PPYR1 Rabbit Polyclonal (Extracellular Domain) Antibody  
Anti-PPYR1 antibody IHC of human brain. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Bear, Bov, Bt, Can, Eq, Hu, Mky, Por, Rb P
50 µg / €400.00
  OriGene Technologies, Inc.

NPY receptor 4 / NPY4R antibody

  PPYR1 Rabbit Polyclonal (Cytoplasmic Domain) Antibody  
Anti-PPYR1 antibody IHC of human brain, substantia nigra. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 16 ug/ml. Rabbit IgG Purified Gorilla, Hu, Mky
50 µg / €400.00
  OriGene Technologies, Inc.

NPY receptor 4 / NPY4R antibody

  Rabbit Polyclonal Anti-Neuropeptide Y4 Receptor  
Western blot analysis of rat brain membrane (lanes 1 and 4), cortex (lanes 2 and 5), and hippocampus (lanes 3 and 6) lysates: 1, 2, 3. Anti-Neuropeptide Y4 Receptor antibody , (1:200). 4, 5, 6. Anti-Neuropeptide Y4 Receptor antibody, preincubated with the control peptide antigen. Rabbit Purified Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

NPY receptor 4 / NPY4R antibody

  Rabbit Polyclonal Anti-NPY4R Antibody  
WB Suggested Anti-PPYR1 Antibody; Titration: 1.0 ug/ml; Positive Control: HepG2 Whole Cell Rabbit IgG Purified Hu, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

NPY receptor 4 / NPY4R antibody

  Rabbit Polyclonal Anti-NPY4R Antibody  
NPY receptor 4 / NPY4R Rabbit IgG Purified Hu E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

CRISPR

Catalog No. Species Donor Vector  

NPY4R - human gene knockout kit via CRISPR

NPY4R - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

NPY4R - human gene knockout kit via CRISPR

NPY4R - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

NPY4R - human gene knockout kit via CRISPR

NPY4R - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

NPY4R - human gene knockout kit via CRISPR

NPY4R - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

NPY4R overexpression lysate

NPY4R overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, NPY4R (mGFP-tagged) - Human pancreatic polypeptide receptor 1 (PPYR1), 200 uL, >10^7 TU/mL

Lenti ORF particles, NPY4R (mGFP-tagged) - Human pancreatic polypeptide receptor 1 (PPYR1), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, NPY4R (Myc-DDK tagged) - Human pancreatic polypeptide receptor 1 (PPYR1) , 200 uL, >10^7 TU/mL

Lenti ORF particles, NPY4R (Myc-DDK tagged) - Human pancreatic polypeptide receptor 1 (PPYR1) , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Ppyr1 (GFP-tagged ORF) - Rat pancreatic polypeptide receptor 1 (Ppyr1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Ppyr1 (GFP-tagged ORF) - Rat pancreatic polypeptide receptor 1 (Ppyr1), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Ppyr1 (Myc-DDK-tagged ORF) - Rat pancreatic polypeptide receptor 1 (Ppyr1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Ppyr1 (Myc-DDK-tagged ORF) - Rat pancreatic polypeptide receptor 1 (Ppyr1), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

15 Item(s)

per page
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