NR1H3 antibody

Principal name

NR1H3 antibody

Alternative names for NR1H3 antibody

LXRA, Oxysterols receptor LXR-alpha, Liver X receptor alpha, Nuclear orphan receptor LXR-alpha, Nuclear receptor subfamily 1 group H member 3

SwissProt ID

Q13133 (Human), Q5E9B6 (Bovin), Q62685 (Rat), Q9Z0Y9 (Mouse)

Gene ID

10062 (NR1H3), 22259 (Nr1h3)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Rb (Rabbit), Ms (Mouse), Rt (Rat), Chk (Chicken), Por (Porcine), Ze (Zebrafish), Mky (Monkey), Eq (Equine), Gt (Goat), GP (Guinea Pig)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Flow Cytometry (F), Electrophoretic Mobility Shift Assay (EMSA), Immunoprecipitation (IP)

Background of NR1H3 antibody

Liver X receptor alpha (LXR alpha), a NR1 Thyroid Hormone-Like Receptor, has been shown to affect the transport and catabolism of cholesterol as well as fatty acid metabolism. LXR alpha also appears to be an important insulin mediating factor in the regulation of lipogenesis. LXR alpha is known to be activated by oxysterols and to regulate a wide range of genes, including members of the ATP-binding cassette (ABC) superfamily of transporter proteins (ABCA1 and ABCG1), surface constituents of plasma lipoproteins like apolipoprotein E, and cholesterol ester transport protein. The induced expression of LXR alpha may be related to foam-cell formation in atherosclerotic lesions. As a result, LXR alpha has been suggested as a potential therapeutic target for treating atherosclerosis. LXR alpha forms a heterodimer with RXR alpha and binds the DR4-type cis-element. Recently LXR alpha has been shown to act as a cAMP-responsive nuclear modulator of renin and c-myc expression, suggesting a possible involvement of LXR alpha in the cardiovascular system and in general gene transcription.

General readings

Albers,M., et al., (2006) J. Biol. Chem. 281 (8), 4920-4930

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

NR1H3 + NR1H2 antibody

NR1H3 + NR1H2 Rabbit IgG Hu WB
0.1 mg / €640.00
  Abnova Taiwan Corp.

NR1H3 antibody

Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-NR1H3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120°C for 3 min, TA805015)(1:150) Mouse IgG2a OTI1A5 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

NR1H3 antibody

Western Blot: LXR Antibody - WB detection of LXR in human liver. Rabbit IgG Purified Hu, Mky WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

NR1H3 antibody

Western blot analysis of LXR-A in rat liver tissue lysate with LXR-A antibody at (A) 1 and (B) 2 ug/mL. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

NR1H3 antibody

Predicted band size: 50 kDa . Positive control: MCF7 cell lysate. Recommended dilution: 1/500-2000. (Gel: 10%SDS-PAGE Lysate: 40 ug Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute) Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

NR1H3 (Center) antibody

Western blot analysis of NR1H3 Antibody (Center) (Cat. #TA325122) in MCF-7 cell line lysates (35ug/lane). NR1H3 (arrow) was detected using the purified Pab. Rabbit Ig Aff - Purified Hu F, WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

NR1H3 antibody

Western blot analysis of extracts of MCF7 cell lines, using NR1H3 antibody. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

NR1H3 antibody

WB Suggested Anti-NR1H3 Antibody Titration: 2.5 ug/ml; ELISA Titer: 1: 1562500; Positive Control: Jurkat cell lysate Rabbit IgG Purified Bov, Can, Eq, Gt, Hu, Por, Rb WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

NR1H3 antibody

WB Suggested Anti-NR1H3 Antibody Titration: 0.2-1 ug/ml; Positive Control: 721_B cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Gt, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

NR1H3 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY NR1H3 (RC223767, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-NR1H3. Mouse IgG2b OTI1F5 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

NR1H3 (C-term) antibody

Western blot with LXRα Polyclonal Antibody Rabbit IgG Aff - Purified Hu, Ms, Rt WB
0.1 mg / €340.00
  Acris Antibodies GmbH

NR1H3 (N-term) antibody

Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit Hu, Ms, Rt E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

NR1H3 Control Peptide

NR1H3
50 µg / €160.00
  Acris Antibodies GmbH

NR1H3 antibody

NR1H3 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

NR1H3 antibody

Immunofluorescence of purified MaxPab antibody to NR1H3 on HeLa cell. [antibody concentration 10 ug/ml] Mouse Purified Hu E(detection), ICC/IF, WB
50 µg / €370.00
  Abnova Taiwan Corp.

NR1H3 antibody

Western Blot analysis of NR1H3 expression in transfected 293T cell line (H00010062-T02) by NR1H3 MaxPab polyclonal antibody.

Lane 1: NR1H3 transfected lysate(45.70 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

NR1H3 antibody

Western Blot analysis of NR1H3 expression in transfected 293T cell line by NR1H3 monoclonal antibody (M08), clone 3E9.

Lane 1: NR1H3 transfected lysate(45.7 KDa).
Lane 2: Non-transfected lysate. Mouse IgG2a 3E9 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

NR1H3 antibody

The NR1H3/NR1H2 polyclonal antibody ( Cat # PAB6691 ) ( 1 µg/ml ) staining of human spleen lysate ( 35 µg protein in RIPA buffer ) . Primary incubation was 1 hour. Detected by chemiluminescence. Goat Hu, Ms, Rt E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

NR1H3 antibody

Westrn blot analysis of NR1H3 expression in Jurkat cell lysate ( Lane 1 ) and mouse small intestine tissue lysate ( Lane 2 ) . Rabbit Bov, Hu, Ms, Rt WB
0.1 mg / €470.00
  Abnova Taiwan Corp.

NR1H3 antibody

Western blot analysis of LXR in lysates of cells that were transfected with the pCMV6-ENTRY control or pCMV6-ENTRY NR1H3 cDNA using NR1H3/NR1H2 polyclonal antibody ( Cat # PAB12535 ). Rabbit Chk, Hu, Ms, Rt WB
0.1 ml / €470.00
  Abnova Taiwan Corp.

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