NR1H4 / FXR antibody

Principal name

NR1H4 / FXR antibody

Alternative names for NR1H4 / FXR antibody

Bile acid receptor, BAR, HRR1, RIP14, Farnesoid X-activated receptor, Farnesol receptor HRR-1, Nuclear receptor subfamily 1 group H member 4, Retinoid X receptor-interacting protein 14

SwissProt ID

Q3SZL0 (Bovin), Q60641 (Mouse), Q62735 (Rat), Q96RI1 (Human)

Gene ID

9971 (NR1H4), 20186 (Nr1h4), 859169 (Q8SQI1)

Available reactivities

Bov (Bovine), Can (Canine), Chk (Chicken), Hu (Human), Ms (Mouse), Rb (Rabbit), Rt (Rat), Eq (Equine), GP (Guinea Pig), Por (Porcine)

Available hosts

Rabbit, Mouse, Goat

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (F), Frozen Sections (C)

Background of NR1H4 / FXR antibody

The steroid receptor superfamily acts through direct association with DNA sequences known as hormone response elements (HREs) and binds DNA as either homo- or heterodimers. The promiscuous mediator of heterodimerization, RXR, is the receptor for 9-cis retinoic acid, and dimerizes with VDR, TR, PPAR, and several novel receptors including LXR (also referred to as RLD-1) and FXR. FXR and LXR fall into a category of proteins termed “orphan receptors” because of their lack of a defined function, and in the case of LXR, the lack of a defined ligand. FXR has been shown to bind a class of lipid molecules called farnesoids. LXR/RXR heterodimers have highest affinity for DR-4 DNA elements while FXR/RXR heterodimers bind IR-1 elements. Both LXR/RXR and FXR/RXR heterodimers retain their responsiveness to 9-cis retinoic acid.

General readings

Huang W, Ma K, Zhang J, Qatanani M, Cuvillier J, Liu J, Dong B, Huang X, Moore DD.
Nuclear receptor-dependent bile acid signaling is required for normal liver regeneration.
Science. 2006 Apr 14;312(5771):233-6.
PMID: 16614213

17 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

NR1H4 / FXR antibody

TA302484 (1µg/ml) staining of Human Lung lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Can, Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

NR1H4 / FXR antibody

Western Blot: FXR Antibody - Detection of FXR in HeLa nuclear extract using anti-FXR.  ECL 30 minute detection. Rabbit Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

NR1H4 / FXR antibody

WB Suggested Anti-NR1H4 Antibody Titration: 0.2-1 ug/ml; Positive Control: Human Lung Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

NR1H4 / FXR antibody

WB Suggested Anti-NR1H4 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: THP-1 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

NR1H4 / FXR antibody

NR1H4 / FXR Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

NR1H4 / FXR antibody

NR1H4 / FXR Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

NR1H4 / FXR antibody

Immunofluorescence of monoclonal antibody to NR1H4 on HepG2 cell. [antibody concentration 10 ug/ml] Mouse IgG1 1G11 Purified Hu E, ICC/IF, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

NR1H4 / FXR antibody

Immunofluorescence of monoclonal antibody to NR1H4 on HeLa cell. [antibody concentration 10 ug/ml] Mouse IgG1 1B10 Purified Hu E, ICC/IF, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

NR1H4 / FXR antibody

NR1H4 polyclonal antibody ( Cat # PAB7164 ) ( 1 µg/ml ) staining of human lung lysate ( 35 µg protein in RIPA buffer ) . Primary incubation was 1 hour. Detected by chemiluminescence. Goat Hu E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

NR1H4 / FXR antibody

Western blot analysis of NR1H4 in HeLa nuclear extract using NR1H4 polyclonal antibody ( Cat # PAB12369 ). ECL 30 minute Western blot analysis. Rabbit Hu WB
0.1 ml / €470.00
  Abnova Taiwan Corp.

NR1H4 / FXR antibody

Human kidney; NR1H4 antibody - middle region (ARP33672_P050) in Human kidney cells using Immunohistochemistry Rabbit Aff - Purified Bov, Can, Chk, Hu, Ms, Rb, Rt P, WB
50 µg / €350.00
  AVIVA Systems Biology

NR1H4 / FXR antibody

Human THP-1; WB Suggested Anti-NR1H4 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: THP-1 cell lysate; NR1H4 antibody - middle region (ARP45626_P050) in Human THP-1 cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

NR1H4 / FXR antibody

NR1H4 / FXR Mouse IgG2a A9033A Purified Hu, Ms, Rt C, ELISA, P, WB
0.1 ml / €640.00
  Funakoshi Co., Ltd.

NR1H4 / FXR antibody

Mouse Anti-NR1H4 (bile acid receptor isoform 2) monoclonal antibody, clone 322.1.2.2 Mouse IgG1 322.1.2.2 Purified Hu E, F, P, WB
0.1 mg / €340.00
  Protein Alternatives

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

NR1H4 / FXR

NR1H4 / FXR Human
10 µg / €380.00
  Abnova Taiwan Corp.

NR1H4 / FXR

NR1H4 / FXR Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

NR1H4 / FXR

NR1H4 / FXR Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

17 Item(s)

per page
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