NR2F6 antibody

Principal name

NR2F6 antibody

Alternative names for NR2F6 antibody

EAR2, ERBAL2, Nuclear receptor subfamily 2 group F member 6,Orphan nuclear receptor EAR-2, V-erbA-related protein EAR-2

SwissProt ID

O09017 (Rat), P10588 (Human), P43136 (Mouse)

Gene ID

2063 (NR2F6), 245980 (Nr2f6)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Can (Canine), Ze (Zebrafish), African clawed frog, Bov (Bovine), Por (Porcine), GP (Guinea Pig)

Available hosts

Rabbit, Mouse, Goat

Available applications

Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Background of NR2F6 antibody

Transcription factor predominantly involved in transcriptional repression. Binds to promoter/enhancer response elements that contain the imperfect 5'-AGGTCA-3' direct or inverted repeats with various spacings which are also recognized by other nuclear hormone receptors. Involved in modulation of hormonal responses. Represses transcriptional activity of the lutropin-choriogonadotropic hormone receptor/LHCGR gene, the renin/REN gene and the oxytocin-neurophysin/OXT gene. Represses the triiodothyronine-dependent and -independent transcriptional activity of the thyroid hormone receptor gene in a cell type-specific manner. The corepressing function towards thyroid hormone receptor beta/THRB involves at least in part the inhibition of THRB binding to triiodothyronine response elements (TREs) by NR2F6. Inhibits NFATC transcription factor DNA binding and subsequently its transcriptional activity. Acts as transcriptional repressor of IL-17 expression in Th-17 differentiated CD4(+) T cells and may be involved in induction and/or maintenance of peripheral immunological tolerance and autoimmunity. Involved in development of forebrain circadian clock; is required early in the development of the locus coeruleus (LC).

General readings

1. Weatherford ET  et al. Regulation of renin expression by the orphan nuclear receptors Nr2f2 and Nr2f6. Am J Physiol Renal Physiol 302:F1025-33 (2012). WB .PubMed: 22278040
2. Modica S  et al. The intestinal nuclear receptor signature with epithelial localization patterns and expression modulation in tumors. Gastroenterology 138:636-48, 648.e1-12 (2010). IHC-P ; Human .PubMed: 19818784

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

NR2F6 antibody

  Rabbit polyclonal anti-NR2F6 antibody  
Western blot analysis of extracts from HeLa cells, 293 cells and HUVEC cells, using NR2F6 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

NR2F6 antibody

  Rabbit Polyclonal Anti-NR2F6 Antibody  
WB Suggested Anti-NR2F6 Antibody; Titration: 0.2 ug/ml; Positive Control: Jurkat Whole Cell Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

NR2F6 antibody

  Rabbit Polyclonal Anti-NR2F6 Antibody  
WB Suggested Anti-NR2F6 Antibody; Titration: 5 ug/ml; Positive Control: HepG2 Whole Cell NR2F6 is strongly supported by BioGPS gene expression data to be expressed in Human HepG2 cells Rabbit IgG Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

NR2F6 antibody

  Rabbit Polyclonal Anti-NR2F6 Antibody  
WB Suggested Anti-NR2F6 Antibody Titration: 5.0ug/ml; ELISA Titer: 1: 1562500; Positive Control: HepG2 cell lysateNR2F6 is strongly supported by BioGPS gene expression data to be expressed in Human HepG2 cells Rabbit IgG Purified Bov, Can, Hu, Ms, Por, Rt, Ze WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

NR2F6 antibody

  Rabbit Polyclonal Anti-NR2F6 Antibody  
WB Suggested Anti-NR2F6 Antibody Titration: 0.2-1 ug/ml; Positive Control: HepG2 cell lysate. NR2F6 is strongly supported by BioGPS gene expression data to be expressed in Human HepG2 cells Rabbit IgG Purified Bov, Can, GP, Hu, Ms, Por, Rt P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

NR2F6 (Ligand-Binding Dom.) antibody

  Rabbit Polyclonal Anti-NR2F6 Antibody (Ligand-binding Domain)  
NR2F6 Rabbit Aff - Purified Hu P
50 µg / €400.00
  OriGene Technologies, Inc.

NR2F6 (N-term) antibody

  Rabbit Polyclonal Anti-NR2F6 Antibody (N-Terminus)  
NR2F6 Rabbit Aff - Purified Hu P
50 µg / €400.00
  OriGene Technologies, Inc.

NR2F6 antibody

  NR2F6 mouse monoclonal antibody, clone OTI2C9 (formerly 2C9)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY NR2F6 (RC201336, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-NR2F6. Mouse IgG2a OTI2C9 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

NR2F6 antibody

  NR2F6 mouse monoclonal antibody, clone OTI2H4 (formerly 2H4)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY NR2F6 (RC201336, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-NR2F6. Mouse IgG2a OTI2H4 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

NR2F6 antibody

NR2F6 Mouse IgG2a EM-51 Purified Hu WB
0.1 mg / €260.00
  Acris Antibodies GmbH

NR2F6 antibody

Immunohistochemistry (IHC) analyzes of EAR2 antibody (Cat.-No.: AP06664PU-N) in paraffin-embedded human cervix carcinoma tissue. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

NR2F6 (N-term) antibody

NR2F6 Antibody (N-term) (Cat. #AP52933PU-N) western blot analysis in MCF-7 cell line lysates (35µg/lane).This demonstrates the NR2F6 antibody detected the NR2F6 protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

NR2F6 antibody

Immunohistochemistry analysis of paraffin-embedded human cervix carcinoma tissue, using NR2F6 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
50 µg / €230.00
  Assay Biotech

NR2F6 antibody

Immunohistochemistry analysis of paraffin-embedded human cervix carcinoma tissue, using NR2F6 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

NR2F6 - human gene knockout kit via CRISPR

NR2F6 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

NR2F6 - human gene knockout kit via CRISPR

NR2F6 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

NR2F6 - human gene knockout kit via CRISPR

NR2F6 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

NR2F6 - human gene knockout kit via CRISPR

NR2F6 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

NR2F6

  Recombinant protein of human nuclear receptor subfamily 2, group F, member 6 (NR2F6)  
NR2F6 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Nr2f6 (GFP-tagged ORF) - Rat nuclear receptor subfamily 2, group F, member 6 (Nr2f6), 200 uL, >10^7 TU/mL

Lenti ORF particles, Nr2f6 (GFP-tagged ORF) - Rat nuclear receptor subfamily 2, group F, member 6 (Nr2f6), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

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