NRCAM antibody

Principal name

NRCAM antibody

Alternative names for NRCAM antibody

Nr-CAM, Neuronal cell adhesion molecule, Bravo, KIAA0343, Neuronal surface protein Bravo, NgCAM-related cell adhesion molecule, Ng-CAM-related

SwissProt ID

P35331 (Chick), P97686 (Rat), Q4KMQ7, Q810U4 (Mouse), Q92823 (Human)

Gene ID

4897 (NRCAM), 319504 (Nrcam)

Available reactivities

Hu (Human), Bov (Bovine), Ms (Mouse), Rt (Rat), Can (Canine), Chk (Chicken), Ze (Zebrafish), African clawed frog, Eq (Equine), Por (Porcine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of NRCAM antibody

Cell adhesion molecules (CAMs) are members of the immunoglobulin superfamily. NRCAM is a neuronal cell adhesion molecule with multiple immunoglobulin-like C2-type domains and fibronectin type-III domains. This ankyrin-binding protein is involved in neuron-neuron adhesion and promotes directional signaling during axonal cone growth. NRCAM may also play a general role in cell-cell communication via signaling from its intracellular domain to the actin cytoskeleton during directional cell migration. Allelic variants of its gene have been associated with autism and addiction vulnerability.Cell adhesion molecules (CAMs) are members of the immunoglobulin superfamily. This gene encodes a neuronal cell adhesion molecule with multiple immunoglobulin-like C2-type domains and fibronectin type-III domains. This ankyrin-binding protein is involved in neuron-neuron adhesion and promotes directional signaling during axonal cone growth. This gene is also expressed in non-neural tissues and may play a general role in cell-cell communication via signaling from its intracellular domain to the actin cytoskeleton during directional cell migration. Allelic variants of this gene have been associated with autism and addiction vulnerability. Alternative splicing results in multiple transcript variants encoding different isoforms.

General readings

Ishiguro,H., (er) Neuropsychopharmacology (2005) In press

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

NRCAM antibody

  Rabbit Polyclonal Anti-NRCAM Antibody  
WB Suggested Anti-NRCAM Antibody Titration: 0.2-1 ug/ml; Positive Control: Jurkat cell lysate Rabbit IgG Purified Bov, Can, Eq, Hu, Por, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

NRCAM antibody

  Rabbit Polyclonal Anti-NRCAM Antibody  
WB Suggested Anti-NRCAM Antibody Titration: 2.5 ug/ml; Positive Control: HepG2 cell lysate Rabbit IgG Purified Eq, GP, Hu, Ms, Rb, Rt P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

NRCAM antibody

Immunofluorescence staining of a node of Ranvier in adult rat sciatic nerve with N343/26 (green) and ßIV-spectrin
rabbit polyclonal (red). Image courtesy of Kae-Jiun Chang and Matt Rasband (Baylor College of Medicine). Mouse IgG2a N343/26 Supernatant Ms, Rt ICC/IF, WB
5 ml / €460.00
  Antibodies Incorporated

NeuroMab

NRCAM antibody

Immunofluorescence staining of a node of Ranvier in adult rat sciatic nerve with N343/26 (green) and ßIV-spectrin
rabbit polyclonal (red). Image courtesy of Kae-Jiun Chang and Matt Rasband (Baylor College of Medicine). Mouse IgG2a N343/26 Purified Ms, Rt ICC/IF, WB
0.1 ml / €540.00
  Antibodies Incorporated

NeuroMab

NRCAM (30-845, Extracell. Dom.) antibody

NRCAM Mouse IgG2a S364-51 Purified Ms, Rt ICC/IF, WB
0.1 mg / €380.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

NRCAM - human gene knockout kit via CRISPR

NRCAM - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

NRCAM - human gene knockout kit via CRISPR

NRCAM - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

NRCAM - human gene knockout kit via CRISPR

NRCAM - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

NRCAM - human gene knockout kit via CRISPR

NRCAM - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Nrcam - mouse gene knockout kit via CRISPR

Nrcam - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Nrcam - mouse gene knockout kit via CRISPR

Nrcam - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Nrcam - mouse gene knockout kit via CRISPR

Nrcam - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Nrcam - mouse gene knockout kit via CRISPR

Nrcam - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

NRCAM (transcript variant 2)

  Purified recombinant protein of Human neuronal cell adhesion molecule (NRCAM), transcript variant 2  
NRCAM Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
10 µg / €139.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, NRCAM (mGFP-tagged)-Human neuronal cell adhesion molecule (NRCAM), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, NRCAM (mGFP-tagged)-Human neuronal cell adhesion molecule (NRCAM), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €2,530.00
  OriGene Technologies, Inc.

Lenti ORF particles, NRCAM (mGFP-tagged)-Human neuronal cell adhesion molecule (NRCAM), transcript variant 4, 200 uL, >10^7 TU/mL

Lenti ORF particles, NRCAM (mGFP-tagged)-Human neuronal cell adhesion molecule (NRCAM), transcript variant 4, 200 uL, >10^7 TU/mL  
200 µl / €2,370.00
  OriGene Technologies, Inc.

Lenti ORF particles, NRCAM (mGFP-tagged)-Human neuronal cell adhesion molecule (NRCAM), transcript variant 5, 200 uL, >10^7 TU/mL

Lenti ORF particles, NRCAM (mGFP-tagged)-Human neuronal cell adhesion molecule (NRCAM), transcript variant 5, 200 uL, >10^7 TU/mL  
200 µl / €1,320.00
  OriGene Technologies, Inc.

Lenti ORF particles, NRCAM (mGFP-tagged)-Human neuronal cell adhesion molecule (NRCAM), transcript variant 6, 200 uL, >10^7 TU/mL

Lenti ORF particles, NRCAM (mGFP-tagged)-Human neuronal cell adhesion molecule (NRCAM), transcript variant 6, 200 uL, >10^7 TU/mL  
200 µl / €1,320.00
  OriGene Technologies, Inc.

Lenti ORF particles, NRCAM (Myc-DDK-tagged)-Human neuronal cell adhesion molecule (NRCAM), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, NRCAM (Myc-DDK-tagged)-Human neuronal cell adhesion molecule (NRCAM), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €2,280.00
  OriGene Technologies, Inc.

Lenti ORF particles, NRCAM (Myc-DDK-tagged)-Human neuronal cell adhesion molecule (NRCAM), transcript variant 4, 200 uL, >10^7 TU/mL

Lenti ORF particles, NRCAM (Myc-DDK-tagged)-Human neuronal cell adhesion molecule (NRCAM), transcript variant 4, 200 uL, >10^7 TU/mL  
200 µl / €2,140.00
  OriGene Technologies, Inc.

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