NSMCE2 antibody

Principal name

NSMCE2 antibody

Alternative names for NSMCE2 antibody

C8orf36, MMS21, E3 SUMO-protein ligase NSE2

SwissProt ID

Q4V8A0 (Rat), Q91VT1 (Mouse), Q96MF7 (Human)

Gene ID

286053 (NSMCE2)

Available reactivities

Hu (Human), Bov (Bovine), Ms (Mouse), Rt (Rat), Eq (Equine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P), Flow Cytometry (F)

Background of NSMCE2 antibody

Breaks in double stranded DNA often arise during DNA replication or as a result of exposure to DNA-damaging agents. Quick and accurate repair of these breaks is crucial for cell survival and genomic stability. Structural maintenance of chromosomes (SMC) family members form heterodimeric complexes that modulate sister chromatid cohesion and chromosome condensation during mitosis. SMC5 and SMC6 play a crucial role in DNA repair as they form a complex with six conserved nonSMC subunits, including a ubiquitin E3 ligase NSE1 and a SUMO ligase NSE2. Specifically, this complex is crucial for sister chromatid homologous recombination DNA repair and also for prevention of chromosomal rearrangements. The NSE1 protein contains a RING-like motif that promotes DNA repair functions of the SMC5/SMC6 complex and full deletion of NSE1 is lethal to cells. NSE2 stimulates sumoylation of SMC6 and the DNA repair protein TRAX. Depletion of the NSE2 protein by RNA interference leaves the cell vulnerable to DNA damage-induced apoptosis.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

NSMCE2 antibody

Anti-NSMCE2 mouse monoclonal antibody (TA501634) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY NSMCE2(RC207639). Mouse IgG1 OTI4H9 Purified Hu F, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

NSMCE2 antibody

Anti-NSMCE2 mouse monoclonal antibody (TA501635) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY NSMCE2(RC207639). Mouse IgG2a OTI6A6 Purified Hu F, ICC/IF, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

NSMCE2 (C-term) antibody

Western blot analysis of MMS21 in 293 cell lysate with MMS21 antibody at (A) 0.5 and (B) 1 ug/mL. Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

NSMCE2 antibody

WB Suggested Anti-NSMCE2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: MCF7 cell lysate Rabbit IgG Purified Bov, Eq, GP, Hu, Ms, Rb WB
50 µg / €325.00
  OriGene Technologies, Inc.

NSMCE2 antibody

Anti-NSMCE2 mouse monoclonal antibody (TA501632) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY NSMCE2(RC207639). Mouse IgG1 OTI4A2 Purified Hu F, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

NSMCE2 antibody

Anti-NSMCE2 mouse monoclonal antibody (TA501633) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY NSMCE2(RC207639). Mouse IgG1 OTI3C10 Purified Hu F, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

NSMCE2 control peptide

NSMCE2
50 µg / €160.00
  Acris Antibodies GmbH

NSMCE2 antibody

Immunofluorescence of purified MaxPab antibody to NSMCE2 on HeLa cell. [antibody concentration 10 ug/ml] Mouse Serum Hu E(detection), ICC/IF, WB
50 µl / €370.00
  Abnova Taiwan Corp.

NSMCE2 antibody

Immunofluorescence of purified MaxPab antibody to NSMCE2 on HeLa cell. [antibody concentration 10 ug/ml] Mouse Purified Hu E(detection), ICC/IF, WB
50 µg / €370.00
  Abnova Taiwan Corp.

NSMCE2 antibody

Human MCF-7; WB Suggested Anti-NSMCE2 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: MCF7 cell lysate; NSMCE2 antibody - middle region (ARP55690_P050) in Human MCF-7 cells using Western Blot Rabbit Aff - Purified Bov, Hu, Ms WB
50 µg / €350.00
  AVIVA Systems Biology

NSMCE2 antibody

Western Blot: NSE2 Antibody [NBP1-56293] - This Anti-NSMCE2 antibody was used in Western Blot of MCF7     tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu WB
50 µg / €440.00
  Novus Biologicals Inc.

NSMCE2 antibody

Immunohistochemistry-Paraffin: Nse2 Antibody [NBP1-76263] - Rat liver tissue with SUMO2/3 antibody at 5 ug/mL._x000d_ Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

NSMCE2 (full length, N-term HIS tag)

NSMCE2 Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
50 µg / €199.00
  OriGene Technologies, Inc.

NSMCE2

NSMCE2 Human Purified
2 µg / €300.00
  Abnova Taiwan Corp.

NSMCE2

NSMCE2 Human
10 µg / €380.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

NSMCE2 293T Cell Transient Overexpression Lysate(Denatured)

NSMCE2 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

16 Item(s)

per page
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