NUDT1 antibody

Principal name

NUDT1 antibody

Alternative names for NUDT1 antibody

7,8-dihydro-8-oxoguanine triphosphatase, 8-oxo-dGTPase, MTH1, Nucleoside diphosphate-linked moiety X motif 1

SwissProt ID

P36639 (Human), P53368 (Mouse), P53369 (Rat)

Gene ID

4521 (NUDT1), 17766 (Nudt1), 117260

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Frozen Sections (C), EPair for Elisa (EPair), Immunoprecipitation (IP), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of NUDT1 antibody

Misincorporation of oxidized nucleoside triphosphates into D/R during replication and transcription can cause mutations that may result in carcinogenesis or neurodegeneration. The protein encoded by this gene is an enzyme that hydrolyzes oxidized purine nucleoside triphosphates, such as 8-oxo-dGTP, 8-oxo-dATP, 2-hydroxy-dATP, and 2-hydroxy rATP, to monophosphates, thereby preventing misincorporation. The encoded protein is localized mainly in the cytoplasm, with some in the mitochondria, suggesting that it is involved in the sanitization of nucleotide pools both for nuclear and mitochondrial genomes. Several altertively spliced transcript variants, some of which encode distinct isoforms, have been identified. Additiol variants have been observed, but their full-length tures have not been determined. A single-nucleotide polymorphism that results in the production of an additiol, longer isoform (p26) has been described.

General readings

Satoh J., et al. (2000) Eur J Neurol. 7(6): 673-677. Choi KM., et al. (2015) FEBS Lett. 589(3): 349-357.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

NUDT1 antibody

  Rabbit Polyclonal MTH1 Antibody  
Western Blot: MTH1 Antibody Rabbit Purified Hu, Ms, Rt C, ICC/IF, WB
0.2 ml / €325.00
  OriGene Technologies, Inc.

NUDT1 antibody

  Rabbit anti-NUDT1 Polyclonal Antibody  
Western blot analysis of extracts of various cell lines, using NUDT1 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

NUDT1 antibody

The Cell lysates (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human NUDT1 antibody (1:500). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.

Lane 1.: K-562 cell lysate 
Lane 2.: SW480 cell lysate
Lane 3.: THP-1 cell lysate
Lane 4.: Jurkat cell lysate
Lane 5.: A549 cell lysate Mouse IgG1 AT3B3 Purified Hu E, WB
0.1 ml / €310.00
  Acris Antibodies GmbH

NUDT1 antibody

The Cell lysates (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human NUDT1 antibody (1:500). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.

Lane 1.: K-562 cell lysate 
Lane 2.: SW480 cell lysate
Lane 3.: THP-1 cell lysate
Lane 4.: Jurkat cell lysate
Lane 5.: A549 cell lysate Mouse IgG1 AT3B3 Purified Hu E, WB
50 µl / €220.00
  Acris Antibodies GmbH

NUDT1 antibody

NUDT1 Mouse Hu WB
50 µg / €370.00
  Abnova Taiwan Corp.

NUDT1 antibody

NUDT1 MaxPab rabbit polyclonal antibody. Western Blot analysis of NUDT1 expression in human kidney. Rabbit Serum Hu E(detection), IP, WB
0.1 ml / €380.00
  Abnova Taiwan Corp.

NUDT1 antibody

NUDT1 MaxPab rabbit polyclonal antibody. Western Blot analysis of NUDT1 expression in human kidney. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

NUDT1 antibody

Western Blot analysis of NUDT1 expression in transfected 293T cell line by NUDT1 monoclonal antibody (M02), clone 5F11.

Lane 1: NUDT1 transfected lysate(18 KDa).
Lane 2: Non-transfected lysate. Mouse IgG2a 5F11 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

NUDT1 antibody

Western blot analysis of NUDT1 in NT2 cells ( Lanes 1-3 ), and 833K64Cp9 cells ( Lanes 4-5 ) with NUDT1 polyclonal antibody ( Cat# PAB12088 ). Western Blot courtesy of Mark Kelley, Indiana University. Rabbit Hu, Ms, Rt C, WB
0.1 ml / €390.00
  Abnova Taiwan Corp.

NUDT1 antibody

Western blot analysis of MTH1 expression in A549 (A); mouse liver (B); rat brain  (C) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rt WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

NUDT1 antibody

Western blot analysis of MTH1 expression in A549 (A); mouse liver (B); rat brain  (C) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rt WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

NUDT1 antibody

Western blot analysis of MTH1 expression in A549 (A); mouse liver (B); rat brain  (C) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rt WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

CRISPR

Catalog No. Species Donor Vector  

NUDT1 - human gene knockout kit via CRISPR

NUDT1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

NUDT1 - human gene knockout kit via CRISPR

NUDT1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

NUDT1 - human gene knockout kit via CRISPR

NUDT1 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

NUDT1 - human gene knockout kit via CRISPR

NUDT1 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Nudt1 - mouse gene knockout kit via CRISPR

Nudt1 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Nudt1 - mouse gene knockout kit via CRISPR

Nudt1 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Nudt1 - mouse gene knockout kit via CRISPR

Nudt1 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Nudt1 - mouse gene knockout kit via CRISPR

Nudt1 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

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