NUDT1 antibody

Principal name

NUDT1 antibody

Alternative names for NUDT1 antibody

7,8-dihydro-8-oxoguanine triphosphatase, 8-oxo-dGTPase, MTH1, Nucleoside diphosphate-linked moiety X motif 1

SwissProt ID

P36639 (Human), P53368 (Mouse), P53369 (Rat)

Gene ID

4521 (NUDT1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse

Available applications

Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), ELISA (detection) (E(detection)), EPair for Elisa (EPair), Immunoprecipitation (IP)

Background of NUDT1 antibody

Misincorporation of oxidized nucleoside triphosphates into DNA/RNA during replication and transcription can cause mutations that may result in carcinogenesis or neurodegeneration. The protein encoded by this gene is an enzyme that hydrolyzes oxidized purine nucleoside triphosphates, such as 8-oxo-dGTP, 8-oxo-dATP, 2-hydroxy-dATP, and 2-hydroxy rATP, to monophosphates, thereby preventing misincorporation. The encoded protein is localized mainly in the cytoplasm, with some in the mitochondria, suggesting that it is involved in the sanitization of nucleotide pools both for nuclear and mitochondrial genomes. Several alternatively spliced transcript variants, some of which encode distinct isoforms, have been identified. Additional variants have been observed, but their full-length natures have not been determined. A single-nucleotide polymorphism that results in the production of an additional, longer isoform (p26) has been described. [provided by RefSeq]. Transcript Variant: This variant (3B) differs in the 5' UTR and 5' coding region compared to variant 1, resulting in translation initiation at an upstream ATG and an isoform (p22, also known as MTH1b) with a longer N-terminus compared to isoform p18. Variants 2B, 3B, and 4B encode the same isoform. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

Satoh J., et al. (2000) Eur J Neurol. 7(6): 673-677. Choi KM., et al. (2015) FEBS Lett. 589(3): 349-357.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

NUDT1 antibody

Western Blot: MTH1 Antibody Rabbit Purified Hu, Ms, Rt C, ICC/IF, WB
0.2 ml / €325.00
  OriGene Technologies, Inc.

NUDT1 antibody

Western blot analysis of extracts of various cell lines, using NUDT1 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

NUDT1 antibody

The Cell lysates (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human NUDT1 antibody (1:500). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.

Lane 1.: K-562 cell lysate 
Lane 2.: SW480 cell lysate
Lane 3.: THP-1 cell lysate
Lane 4.: Jurkat cell lysate
Lane 5.: A549 cell lysate Mouse IgG1 AT3B3 Purified Hu E, WB
0.1 ml / €310.00
  Acris Antibodies GmbH

NUDT1 antibody

The Cell lysates (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human NUDT1 antibody (1:500). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.

Lane 1.: K-562 cell lysate 
Lane 2.: SW480 cell lysate
Lane 3.: THP-1 cell lysate
Lane 4.: Jurkat cell lysate
Lane 5.: A549 cell lysate Mouse IgG1 AT3B3 Purified Hu E, WB
50 µl / €220.00
  Acris Antibodies GmbH

NUDT1 antibody

NUDT1 Mouse Hu WB
50 µg / €370.00
  Abnova Taiwan Corp.

NUDT1 antibody

NUDT1 MaxPab rabbit polyclonal antibody. Western Blot analysis of NUDT1 expression in human kidney. Rabbit Serum Hu E(detection), IP, WB
0.1 ml / €380.00
  Abnova Taiwan Corp.

NUDT1 antibody

NUDT1 MaxPab rabbit polyclonal antibody. Western Blot analysis of NUDT1 expression in human kidney. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

NUDT1 antibody

Western Blot analysis of NUDT1 expression in transfected 293T cell line by NUDT1 monoclonal antibody (M02), clone 5F11.

Lane 1: NUDT1 transfected lysate(18 KDa).
Lane 2: Non-transfected lysate. Mouse IgG2a 5F11 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

NUDT1 antibody

Western blot analysis of NUDT1 in NT2 cells ( Lanes 1-3 ), and 833K64Cp9 cells ( Lanes 4-5 ) with NUDT1 polyclonal antibody ( Cat# PAB12088 ). Western Blot courtesy of Mark Kelley, Indiana University. Rabbit Hu, Ms, Rt C, WB
0.1 ml / €390.00
  Abnova Taiwan Corp.

NUDT1 antibody

Western blot analysis of MTH1 expression in A549 (A); mouse liver (B); rat brain  (C) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rt WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

NUDT1 antibody

Western blot analysis of MTH1 expression in A549 (A); mouse liver (B); rat brain  (C) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rt WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

NUDT1 antibody

Western blot analysis of MTH1 expression in A549 (A); mouse liver (B); rat brain  (C) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rt WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

NUDT1 antibody

NUDT1 Rabbit Biotin Hu, Ms, Rt C, P, WB
0.2 ml / €550.00
  Novus Biologicals Inc.

NUDT1 antibody

NUDT1 Rabbit DyLight488 Hu, Ms, Rt C, P, WB
0.2 ml / €590.00
  Novus Biologicals Inc.

NUDT1 antibody

NUDT1 Rabbit HRP Hu, Ms, Rt C, P, WB
0.2 ml / €590.00
  Novus Biologicals Inc.

NUDT1 antibody

NUDT1 Rabbit Aff - Purified Hu, Ms, Rt C, ICC/IF, P, WB
50 µl / €200.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

NUDT1 (transcript variant 3B)

NUDT1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

NUDT1 (transcript variant 1)

NUDT1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

NUDT1 (transcript variant 2A)

NUDT1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

NUDT1 (transcript variant 2B)

NUDT1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

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