NUDT15 antibody

Principal name

NUDT15 antibody

Alternative names for NUDT15 antibody

MTH2, MutT homolog 2, Nudix motif 15, Probable 8-oxo-dGTP diphosphatase NUDT15, 7,8-dihydro-8-oxoguanine-triphosphatase NUDT15, Nucleoside diphosphate-linked moiety X motif 15

SwissProt ID

Q8BG93 (Mouse), Q9NV35 (Human)

Gene ID

55270 (NUDT15)

Available reactivities

Hu (Human), Ms (Mouse)

Available hosts


Available applications

Western blot / Immunoblot (WB), Flow Cytometry (F), Paraffin Sections (P)

Background of NUDT15 antibody

Mediates the hydrolysis of some nucleoside diphosphate derivatives. Can degrade 8-oxo-dGTP in vitro, suggesting that it may remove an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine) from DNA and the nucleotide pool, thereby preventing misincorporation of 8-oxo-dGTP into DNA thus preventing A:T to C:G transversions. Its substrate specificity in vivo however remains unclear (By similarity). May have a role in DNA synthesis and cell cycle progression throught the interaction with PCNA.

General readings

Hori, M., et al. Free Radic. Biol. Med. 48(9):1197-1201 (2010)
Yu, Y., et al. J. Biol. Chem. 284(29):19310-19320 (2009)
Dunham, A., et al. Nature 428(6982):522-528 (2004)
Cai, J.P., et al. Biochem. Biophys. Res. Commun. 305(4):1073-1077 (2003)

4 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

NUDT15 (C-term) antibody

NUDT15 Rabbit Ig Aff - Purified Hu, Ms F, P, WB
  Acris Antibodies GmbH

NUDT15 antibody

NUDT15 Rabbit IgG Aff - Purified Hu P, WB
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  


NUDT15 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
  OriGene Technologies, Inc.


Catalog No.    

NUDT15 overexpression lysate

NUDT15 overexpression lysate  
  OriGene Technologies, Inc.

4 Item(s)

per page
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