NUP153 antibody

Principal name

NUP153 antibody

Alternative names for NUP153 antibody

Nucleoporin Nup153, Nuclear pore complex protein Nup153, 153 kDa nucleoporin

SwissProt ID

P49790 (Human), P49791 (Rat)

Gene ID

9972 (NUP153)

Available reactivities

Amph (Amphibian), Hu (Human), Ms (Mouse), Rt (Rat), Xen (Xenopus), Eu (Eukaryote)

Available hosts

Mouse, Rabbit

Available applications

Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Western blot / Immunoblot (WB), Flow Cytometry (F), Paraffin Sections (P)

Background of NUP153 antibody

Nuclear pore complexes are extremely elaborate structures that mediate the regulated movement of macromolecules between the nucleus and cytoplasm. These complexes are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family. Nucleoporins are pore complex specific glycoproteins characterized by cytoplasmically oriented O linked N acetylglucosamine residues and numerous repeats of the pentapeptide sequence XFXFG. Nup153 has three distinct domains: a N terminal region within which a pore targeting domain has been identified, a central region containing multiple zinc finger motifs, and a C terminal region containing multiple XFXFG repeats. Nup153 is a possible DNA binding subunit of the nuclear pore complex (NPC). The repeat containing domain may be involved in anchoring components of the pore complex to the pore membrane.

General readings

Olsen,J.V., et.al., Cell 127 (3), 635-648 (2006)
Ullman,K.S.,et.al., Mol. Biol. Cell 10 (3), 649-664 (1999)

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CRISPR

Catalog No. Species Donor Vector  

NUP153 - human gene knockout kit via CRISPR

NUP153 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

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