NUP98 / ADAR2 antibody

Principal name

NUP98 / ADAR2 antibody

Alternative names for NUP98 / ADAR2 antibody

Nuclear pore complex protein Nup98-Nup96

SwissProt ID

P49793 (Rat), P52948 (Human), Q9Y6J4 (Human)

Gene ID

4928 (NUP98)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Chk (Chicken), Ms (Mouse), Rt (Rat), Ze (Zebrafish), African clawed frog, Eq (Equine), Por (Porcine), Rb (Rabbit), GP (Guinea Pig), Ye (Yeast)

Available hosts

Mouse, Rabbit, Rat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunoprecipitation (IP), Dot blot (Dot), Immunocytochemistry (ICC)

Background of NUP98 / ADAR2 antibody

The nuclear pore complex (NPC) is comprised of approximately 50 unique proteins collectively known as nucleoporins. The 98 kD nucleoporin is localized to the nucleoplasmic side of the NPC. Rat studies show that the 98 kD nucleoporin functions as one of several docking site nucleoporins of transport substrates. The human gene has been shown to fuse to several genes following chromsome translocatons in acute myelogenous leukemia (AML) and T-cell acute lymphocytic leukemia (T-ALL). This gene is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Signal-mediated nuclear import and export proceed through the nuclear pore complex (NPC), which is comprised of approximately 50 unique proteins collectively known as nucleoporins. The 98 kD nucleoporin is generated through a biogenesis pathway that involves synthesis and proteolytic cleavage of a 186 kD precursor protein. This cleavage results in the 98 kD nucleoporin as well as a 96 kD nucleoporin, both of which are localized to the nucleoplasmic side of the NPC. Rat studies show that the 98 kD nucleoporin functions as one of several docking site nucleoporins of transport substrates. The human gene has been shown to fuse to several genes following chromsome translocatons in acute myelogenous leukemia (AML) and T-cell acute lymphocytic leukemia (T-ALL). This gene is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Alternative splicing of this gene results in several transcript variants; however, not all variants have been fully described.

General readings

Pan,Q., (2008) Oncogene 27 (24), 3414-3423

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

NUP98 / ADAR2 antibody

WB Suggested Anti-NUP98 Antibody Titration: 0.2-1 ug/ml; Positive Control: Human Lung Rabbit IgG Purified Bov, Can, Eq, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

NUP98 / ADAR2 antibody

WB Suggested Anti-NUP98 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: Transfected 293T Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt, Ye, Ze ICC/IF, WB
50 µg / €325.00
  OriGene Technologies, Inc.

NUP98 / ADAR2 antibody

Western blot detection of NUP98 in Hela,Jurkat and MCF7 cell lysates using NUP98 mouse mAb (1:1000 diluted).Predicted band size: 98kDa.Observed band size: 98kDa. Mouse IgG1 3B8-D7-H10 Purified WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

NUP98 / ADAR2 antibody

NUP98 / ADAR2 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

NUP98 / ADAR2 antibody

Western Blot analysis of NUP98 expression in transfected 293T cell line (H00007447-T01) by NUP98 MaxPab polyclonal antibody.

Lane 1: NUP98 transfected lysate(66.77 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

NUP98 / ADAR2 antibody

Western Blot analysis of NUP98 expression in transfected 293T cell line (H00004928-T02) by NUP98 MaxPab polyclonal antibody.

Lane 1: NUP98 transfected lysate(66.66 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

NUP98 / ADAR2 antibody

NUP98 / ADAR2 Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

NUP98 / ADAR2 antibody

NUP98 / ADAR2 Rabbit Serum Hu IP, WB
0.1 ml / €380.00
  Abnova Taiwan Corp.

NUP98 / ADAR2 antibody

Western Blot analysis of NUP98 expression in transfected 293T cell line (H00004928-T02) by NUP98 MaxPab polyclonal antibody.

Lane 1: NUP98 transfected lysate(69.80 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

NUP98 / ADAR2 antibody

NUP98 / ADAR2 Mouse IgG2a 4G2 Purified Hu E
0.1 mg / €370.00
  Abnova Taiwan Corp.

NUP98 / ADAR2 antibody

Human HeLa; Immunofluorescence -- Sample Type: HeLa cellsDilution: 2ug/mL; NUP98 antibody - N-terminal region (ARP39251_P050) in Human HeLa cells using Immunofluorescence Rabbit Aff - Purified African clawed frog, Bov, Can, Chk, Hu, Ms, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

NUP98 / ADAR2 antibody

Human Lung; WB Suggested Anti-NUP98 Antibody Titration: 0.2-1 ug/ml. Positive Control: Human Lung; NUP98 antibody - N-terminal region (ARP53631_P050) in Human Lung cells using Western Blot Rabbit Aff - Purified Bov, Can, Chk, Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

NUP98 / ADAR2 antibody

NUP98 / ADAR2 Rat IgG2c 2H10 Purified Hu, Ms, Rt Dot, ELISA, ICC, WB
0.2 mg / €430.00
  Funakoshi Co., Ltd.

NUP98 / ADAR2 antibody

Western Blot and  Immunoprecipitation: NUP96 Antibody [NB100-93325] - Detection of Human NUP96 on HeLa whole cell lysate using NB100-93325. NUP96 was also immunoprecipitated by rabbit anti-NUP96 antibody NB100-93326. Rabbit IgG Aff - Purified Hu IP, WB
0.1 ml / €440.00
  Novus Biologicals Inc.

NUP98 / ADAR2 antibody

Western Blot and  Immunoprecipitation: NUP98 Antibody [NB100-93327] - Detection of Human NUP98 on HeLa whole cell lysate using NB100-93327. NUP98 was also immunoprecipitated by another rabbit anti-NUP98 antibody. Rabbit IgG Aff - Purified Hu IP, WB
0.1 ml / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

NUP98 / ADAR2

NUP98 / ADAR2 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

NUP98 / ADAR2

NUP98 / ADAR2 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

NUP98 / ADAR2

NUP98 / ADAR2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

NUP98 / ADAR2

NUP98 / ADAR2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Antibody Pairs

Catalog No.    

NUP98 (Human) IP-WB Antibody Pair

NUP98 (Human) IP-WB Antibody Pair  
1 set / €710.00
  Abnova Taiwan Corp.

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