NXF1 antibody

Principal name

NXF1 antibody

Alternative names for NXF1 antibody

TAP, Nuclear RNA export factor 1, Tip-associating protein, Tip-associated protein, mRNA export factor TAP

SwissProt ID

Q9UBU9 (Human)

Gene ID

10482 (NXF1)

Available reactivities

Bov (Bovine), Can (Canine), Hu (Human), Ms (Mouse), Rt (Rat), Mky (Monkey), Eq (Equine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Immunoprecipitation (IP), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of NXF1 antibody

NXF1 is one member of a family of nuclear RNA export factor. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. NXF1 shuttles between the nucleus and the cytoplasm and binds in vivo to poly(A)+ RNA. NXF1 overcomes the mRNA export block caused by the presence of saturating amounts of CTE (constitutive transport element) RNA of type D retroviruses.This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene shuttles between the nucleus and the cytoplasm and binds in vivo to poly(A)+ RNA. It is the vertebrate homologue of the yeast protein Mex67p. The encoded protein overcomes the mRNA export block caused by the presence of saturating amounts of CTE (constitutive transport element) RNA of type D retroviruses.This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene shuttles between the nucleus and the cytoplasm and binds in vivo to poly(A)+ RNA. It is the vertebrate homologue of the yeast protein Mex67p. The encoded protein overcomes the mRNA export block caused by the presence of saturating amounts of CTE (constitutive transport element) RNA of type D retroviruses.

General readings

Chen,I.H., (2005) J. Virol. 79 (7), 3949-3961

10 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

NXF1 antibody

  Rabbit Polyclonal antibody to TAP (nuclear RNA export factor 1)  
Sample (50 ug of whole cell lysate). A: Mouse brain. 7.5% SDS PAGE. TA308021 diluted at 1:1000. Rabbit IgG Aff - Purified Hu, Ms ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

NXF1 antibody

  Rabbit polyclonal antibody to TAP (nuclear RNA export factor 1)  
Sample (30 ug of whole cell lysate). A: Hela. B: Molt-4 . 7.5% SDS PAGE. TA308497 diluted at 1:1000. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

NXF1 antibody

  Rabbit polyclonal NXF1 antibody  
Western blot analysis of extracts from HepG2 cells, Jurkat cells and HeLa cells, using NXF1 antibody. Rabbit IgG Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

NXF1 antibody

  Rabbit Polyclonal Anti-NXF1 Antibody  
WB Suggested Anti-NXF1 Antibody Titration: 0.2-1 ug/ml; Positive Control: HepG2 cell lysateNXF1 is supported by BioGPS gene expression data to be expressed in HepG2 Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

NXF1 antibody

  Rabbit Polyclonal Anti-NXF1 Antibody  
WB Suggested Anti-NXF1 Antibody Titration: 1.25 ug/ml; Positive Control: HepG2 cell lysateNXF1 is supported by BioGPS gene expression data to be expressed in HepG2 Rabbit IgG Purified Bov, Can, GP, Hu, Ms, Rt P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

NXF1 antibody

  Rabbit Polyclonal Anti-NXF1 Antibody  
Western blot analysis on HeLa cell lysate using NXF1 Antibody Rabbit IgG Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, NXF1 (mGFP-tagged) - Human nuclear RNA export factor 1 (NXF1), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, NXF1 (mGFP-tagged) - Human nuclear RNA export factor 1 (NXF1), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, NXF1 (mGFP-tagged) - Human nuclear RNA export factor 1 (NXF1), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, NXF1 (mGFP-tagged) - Human nuclear RNA export factor 1 (NXF1), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €930.00
  OriGene Technologies, Inc.

Lenti ORF particles, NXF1 (Myc-DDK tagged) - Human nuclear RNA export factor 1 (NXF1), transcript variant 1 , 200 uL, >10^7 TU/mL

Lenti ORF particles, NXF1 (Myc-DDK tagged) - Human nuclear RNA export factor 1 (NXF1), transcript variant 1 , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Lenti ORF particles, NXF1 (Myc-DDK tagged) - Human nuclear RNA export factor 1 (NXF1), transcript variant 2 , 200 uL, >10^7 TU/mL

Lenti ORF particles, NXF1 (Myc-DDK tagged) - Human nuclear RNA export factor 1 (NXF1), transcript variant 2 , 200 uL, >10^7 TU/mL  
200 µl / €830.00
  OriGene Technologies, Inc.

10 Item(s)

per page
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