Nyctalopin antibody

Principal name

Nyctalopin antibody

Alternative names for Nyctalopin antibody

NYX, CLRP

SwissProt ID

P83503 (Mouse), Q9GZU5 (Human)

Gene ID

60506 (NYX)

Available reactivities

Hu (Human)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB)

Background of Nyctalopin antibody

The product of this gene belongs to the small leucine-rich proteoglycan (SLRP) family of proteins. Defects in this gene are the cause of congenital stationary night blindness type 1 (CSNB1), also called X-linked congenital stationary night blindness (XLCSNB). CSNB1 is a rare inherited retinal disorder characterized by impaired scotopic vision, myopia, hyperopia, nystagmus and reduced visual acuity. The role of other SLRP proteins suggests that mutations in this gene disrupt developing retinal interconnections involving the ON-bipolar cells, leading to the visual losses seen in patients with complete CSNB. [provided by RefSeq].

General readings

Leroy, B.P., et al. Br J Ophthalmol 93(5):692-696(2009)
Zhang, Q., et al. Mol. Vis. 13, 330-336 (2007)
Morgans, C.W., et al. Eur. J. Neurosci. 23(5):1163-1171(2006)
Xiao, X., et al. J. Hum. Genet. 51(7):634-640(2006)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Nyctalopin (N-term) antibody

Western blot analysis of Nyctalopin Antibody (N-term) Cat.-No AP52981PU-N in HL-60 cell line lysates (35ug/lane). NYX (arrow) was detected using the purified Pab. Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Nyctalopin

Nyctalopin Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

NYX overexpression lysate

NYX overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

3 Item(s)

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