OAS1 / OIAS antibody

Principal name

OAS1 / OIAS antibody

Alternative names for OAS1 / OIAS antibody

2'-5'-oligoadenylate synthetase 1, p46/p42 OAS, (2-5')oligo(A) synthetase 1, 2-5A synthetase 1

SwissProt ID

P00973 (Human), Q05961 (Rat), Q29599 (Pig)

Gene ID

4938 (OAS1)

Available reactivities

Hu (Human), Ms (Mouse), Bov (Bovine), Can (Canine), Chk (Chicken), Por (Porcine), Rt (Rat), Eq (Equine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Paraffin Sections (P), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of OAS1 / OIAS antibody

OAS1 is a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. It is induced by interferons and uses adenosine triphosphate in 2\'-specific nucleotidyl transfer reactions to synthesize 2\',5\'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. Mutations in this gene have been associated with host susceptibility to viral infection.This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2\'-specific nucleotidyl transfer reactions to synthesize 2\',5\'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Mutations in this gene have been associated with host susceptibility to viral infection. Alternatively spliced transcript variants encoding different isoforms have been described.

General readings

Rios JJ., et al. (2007) BMC Genomics. 8:313.
Tessier MC., et al. (2006) J Med Genet. 43(2):129-32.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

OAS1 / OIAS (Isoforms 1) antibody

TA326756 (1µg/ml) staining of HepG2 lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

OAS1 / OIAS antibody

WB Suggested Anti-OAS1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: 293T cell lysateOAS1 is strongly supported by BioGPS gene expression data to be expressed in Human HEK293T cells Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

OAS1 / OIAS antibody

WB Suggested Anti-OAS1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: Transfected 293T Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

OAS1 / OIAS antibody

WB Suggested Anti-OAS1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: Human heart Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

OAS1 / OIAS antibody

WB Suggested Anti-OAS1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 1562500; Positive Control: Human Stomach Rabbit IgG Purified Bov, Can, Eq, Hu, Ms, Por, Rb, Rt P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

OAS1 / OIAS antibody

Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE) Mouse IgG2a 2D4 Hu E, P
50 µg / €530.00
  Acris Antibodies GmbH

OAS1 / OIAS (317-331) antibody

Formalin-Fixed Paraffin-Embedded Human Colon stained with anti-OAS1 Antibody Rabbit Purified Hu E, P
50 µg / €470.00
  Acris Antibodies GmbH

OAS1 / OIAS (C-term) antibody

Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with OAS1 antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining Rabbit Ig Purified Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

OAS1 / OIAS antibody

Western Blot analysis of OAS1 expression in transfected 293T cell line (H00004938-T02) by OAS1 MaxPab polyclonal antibody.

Lane 1: OAS1 transfected lysate(46.00 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

OAS1 / OIAS antibody

Western Blot analysis of OAS1 expression in transfected 293T cell line (H00004938-T03) by OAS1 MaxPab polyclonal antibody.

Lane 1: OAS1 transfected lysate(40.04 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

OAS1 / OIAS antibody

Immunoperoxidase of monoclonal antibody to OAS1 on formalin-fixed paraffin-embedded human colon. [antibody concentration 3 ug/ml] Mouse IgG2a 2D4 Purified Hu E, P
0.1 mg / €370.00
  Abnova Taiwan Corp.

OAS1 / OIAS antibody

Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with OAS1 polyclonal antibody ( Cat # PAB4810 ) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. Rabbit Hu, Ms E, P, WB
0.4 ml / €390.00
  Abnova Taiwan Corp.

OAS1 / OIAS antibody

Human small intestine; Immunohistochemistry with Small intestine tissue at an antibody concentration of 5ug/ml using anti-OAS1 antibody (ARP40401_P050); OAS1 antibody - N-terminal region (ARP40401_P050) in Human small intestine cells using Immunohistochemistry Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

OAS1 / OIAS (Isoform p48) antibody

Human Small intestine; Immunohistochemistry with Small intestine tissue; OAS1 antibody - middle region (ARP51359_P050) in Human Small intestine cells using Immunohistochemistry Rabbit Aff - Purified Bov, Can, Chk, Hu, Ms, Por, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

OAS1 / OIAS antibody

Human heart; WB Suggested Anti-OAS1 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: Human heart; OAS1 antibody - C-terminal region (ARP51360_P050) in Human heart cells using Western Blot Rabbit Aff - Purified Chk, Hu, Ms WB
50 µg / €350.00
  AVIVA Systems Biology

OAS1 / OIAS antibody

Human HEK293T; WB Suggested Anti-OAS1 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: 293T cell lysate. OAS1 is strongly supported by BioGPS gene expression data to be expressed in Human HEK293T cells.; OAS1 antibody - C-terminal region (AVARP20004_P050) in Human HEK293T cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

OAS1 / OIAS antibody

OAS1 / OIAS Rabbit Purified Hu E, ICC/IF, P
50 µg / €480.00
  Novus Biologicals Inc.

OAS1 / OIAS antibody

Western Blot: OAS1 Antibody [NBP1-58950] - This Anti-OAS1 antibody was used in Western Blot of Fetal Heart tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu P, WB
50 µg / €440.00
  Novus Biologicals Inc.

OAS1 / OIAS antibody

Immunohistochemistry-Paraffin: OAS1 Antibody [NBP1-83122] - Immunohistochemical staining of human placenta shows strong nuclear positivity in trophoblastic cells. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

OAS1 / OIAS (transcript variant 2)

OAS1 / OIAS Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

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