OBFC2A antibody

Principal name

OBFC2A antibody

Alternative names for OBFC2A antibody

SOSS-B2, SSB2, Sensor of ssDNA B2, Oligonucleotide/oligosaccharide-binding fold-containing protein 2A, SOSS complex subunit B2, Single-stranded DNA-binding protein 2, Sensor of single-strand DNA complex subunit B2

SwissProt ID

A5D7P8 (Bovin), Q5FVP2 (Rat), Q8BGW5 (Mouse), Q96AH0 (Human)

Gene ID

64859 (NABP1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit

Available applications

Immunoprecipitation (IP), Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of OBFC2A antibody

Nucleic acid binding protein 1, also known as NABP1, is component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. In the SOSS complex, the protein acts as a sensor of single-stranded DNA that binds to single-stranded DNA, in particular to polypyrimidines. The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. This protein is required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways.

General readings

Li Y., et al. (2009) J. Biol. Chem. 284:23525-23531 Huang J., et al. (2009) Mol. Cell. 35:384-393

8 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

OBFC2A antibody

Western Blot : OBFC2A Antibody [NBP1-26639]-Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit  used for IP at 10 mcg/mg lysate. Rabbit IgG Aff - Purified Hu IP
0.1 mg / €440.00
  Novus Biologicals Inc.

OBFC2A antibody

Western Blot : OBFC2A Antibody [NBP1-26640]-Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit used for IP at 10 mcg/mg lysate. Rabbit IgG Aff - Purified Hu IP
0.1 mg / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

OBFC2A (full length, N-term HIS tag, transcript variant 1)

OBFC2A Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
50 µg / €199.00
  OriGene Technologies, Inc.

OBFC2A (1-204, His-tag)

OBFC2A Human Purified > 95 % by SDS - PAGE E. coli
0.5 mg / €730.00
  Acris Antibodies GmbH

OBFC2A (1-204, His-tag)

OBFC2A Human Purified > 95 % by SDS - PAGE E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

OBFC2A

OBFC2A Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

OBFC2A

OBFC2A Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

NABP1 overexpression lysate

NABP1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

8 Item(s)

per page
  • LinkedIn