OGG1 antibody

Principal name

OGG1 antibody

Alternative names for OGG1 antibody

MMH, MUTM, OGH1, N-glycosylase/DNA lyase

SwissProt ID

O08760 (Mouse), O15527 (Human), O70249 (Rat), P53397 (Yeast), Q9V3I8 (Drome)

Gene ID

81528 (Ogg1), 4968 (OGG1), 18294

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Prim (Primate)

Available hosts

Goat, Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Paraffin Sections (P), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Frozen Sections (C)

Background of OGG1 antibody

The Ogg1 gene encodes a DNA repair enzyme (N glycosylase/DNA lyase) that incises DNA at 8 oxoG residues. N glycosylase/DNA lyase excises 7,8 dihydro 8 oxoguanine and 2,6 diamino 4 hydroxy 5 N methylformamidopyrimidine (FAPY) from damaged DNA. N glycosylase/DNA lyase has a beta lyase activity that nicks DNA 3' to the lesion.
Alternative splicing of the C terminal region of the Ogg1 gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N terminal region in common. Many alternative splice variants for this gene have been described, but the full length nature for every variant has not been determined. The N terminus of this gene contains a mitochondrial targetting signal, essential for mitochondrial localization.

General readings

Seeberg E., et al. (2002). Nucleic Acids Res. 30(11):2349-57.
Hodges NJ., et al (2010). DNA Repair (Amst). 9(2):144-52.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

OGG1 antibody

  Rabbit Polyclonal Ogg1 Antibody  
Western Blot: Ogg1 antibody - 1, 5, 10 ng titration of human recombinant Ogg1 protein, detected by anti-Ogg1. Rabbit Purified Hu, Prim, Rt C, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

OGG1 antibody

  Goat Anti-Ogg1 (mouse) Antibody  
TA305839 (0.1ug/ml) staining of Rat Spleen lysate (35ug protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

OGG1 antibody

  Anti-OGG1 Rabbit Polyclonal Antibody  
Predicted band size: 39 kDa . Positive control: Human heart tissue lysate. Recommended dilution: 1/500-2000. (Gel: 10%SDS-PAGE Lysate: 40 ug Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute) Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

OGG1 antibody

Figure 1. Immunohistochemical analysis of Formalin-Fixed Paraffin-Embedded Kidney tissue using AP08789PU-N at 2.5 µg/ml. Goat IgG Aff - Purified Hu, Ms, Rt E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

OGG1 (C-term) antibody

Western blot analysis of OGG1 Antibody (C-term) (AP17606PU-N) in Hela, NIH-3T3 cell line lysates (35ug/lane). OGG1 (arrow) was detected using the purified Pab. Rabbit Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

OGG1 antibody

Immunofluorescence of purified MaxPab antibody to OGG1 on HeLa cell. [antibody concentration 10 ug/ml] Mouse Purified Hu E(detection), ICC/IF, WB
50 µg / €370.00
  Abnova Taiwan Corp.

OGG1 antibody

OGG1 MaxPab rabbit polyclonal antibody. Western Blot analysis of OGG1 expression in Jurkat. Rabbit Serum Hu E(detection), IP, WB
0.1 ml / €380.00
  Abnova Taiwan Corp.

OGG1 antibody

Western Blot analysis of OGG1 expression in transfected 293T cell line (H00004968-T01) by OGG1 MaxPab polyclonal antibody.

Lane 1: OGG1 transfected lysate(36.40 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

OGG1 antibody

The Ogg1 polyclonal antibody ( Cat # PAB7311 ) ( 0.1 µg/ml ) staining of rat spleen lysate ( 35 µg protein in RIPA buffer ) . Primary incubation was 1 hour. Detected by chemiluminescence. Goat Rt E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

OGG1 antibody

Immunohistochemical staining of OGG1 on formaldehyde fixed frozen sections of the substantia nigra from a Rhesus macaque with OGG1 polyclonal antibody ( Cat # PAB12085 ). Photo courtesy of Glen Kisby, Oregon Health Sciences University. The tissue was a generous gift of Dr. Steven Kohama, Oregon National Primate Research Center. Rabbit Hu, Rt C, WB
0.1 ml / €470.00
  Abnova Taiwan Corp.

OGG1 antibody

OGG1 Rabbit IgG Biotin Hu, Prim, Rt C, P, WB
0.1 ml / €400.00
  Neuromics Antibodies

OGG1 antibody

OGG1 Rabbit IgG HRP Hu, Prim, Rt C, P, WB
0.1 ml / €400.00
  Neuromics Antibodies

CRISPR

Catalog No. Species Donor Vector  

Ogg1 - mouse gene knockout kit via CRISPR

Ogg1 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Ogg1 - mouse gene knockout kit via CRISPR

Ogg1 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Ogg1 - mouse gene knockout kit via CRISPR

Ogg1 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Ogg1 - mouse gene knockout kit via CRISPR

Ogg1 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

OGG1 (transcript variant 1a)

  Recombinant protein of human 8-oxoguanine DNA glycosylase (OGG1), nuclear gene encoding mitochondrial protein, transcript variant 1a  
OGG1 Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
10 µg / €299.00
  OriGene Technologies, Inc.

OGG1 (full length, N-term HIS tag, transcript variant 2a)

  Purified recombinant protein of Human 8-oxoguanine DNA glycosylase (OGG1), nuclear gene encoding mitochondrial protein, transcript variant 2a, full length, with N-terminal HIS tag, expressed in E. coli, 50ug  
OGG1 Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
50 µg / €199.00
  OriGene Technologies, Inc.

OGG1 (1-345, His-tag)

OGG1 Human Purified > 90 % by SDS-PAGE E. coli
0.5 mg / €750.00
  Acris Antibodies GmbH

OGG1 (1-345, His-tag)

OGG1 Human Purified > 90 % by SDS-PAGE E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

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