Opticin antibody

Principal name

Opticin antibody

Alternative names for Opticin antibody

OPTC, OPT, Oculoglycan

SwissProt ID

P58874 (Bovin), P83286 (Canfa), Q920A0 (Mouse), Q9UBM4 (Human)

Gene ID

26254 (OPTC)

Available reactivities

Can (Canine), Hu (Human), Ms (Mouse), Por (Porcine), Rt (Rat), Ze (Zebrafish), Eq (Equine), Rb (Rabbit)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB)

Background of Opticin antibody

Opticin belongs to class III of the small leucine-rich repeat protein (SLRP) family. Members of this family are typically associated with the extracellular matrix. Opticin is present in significant quantities in the vitreous of the eye and also ocalizes to the cornea, iris, ciliary body, optic nerve, choroid, reti, and fetal liver. Opticin may noncovalently bind collagen fibrils and regulate fibril morphology, spacing, and organization. The opticin gene is mapped to a region of chromosome 1 that is associated with the inherited eye diseases age-related macular degeneration (AMD) and posterior column ataxia with retinosa pigmentosa (AXPC1).Opticin belongs to class III of the small leucine-rich repeat protein (SLRP) family. Members of this family are typically associated with the extracellular matrix. Opticin is present in significant quantities in the vitreous of the eye and also localizes to the cornea, iris, ciliary body, optic nerve, choroid, reti, and fetal liver. Opticin may noncovalently bind collagen fibrils and regulate fibril morphology, spacing, and organization. The opticin gene is mapped to a region of chromosome 1 that is associated with the inherited eye diseases age-related macular degeneration (AMD) and posterior column ataxia with retinosa pigmentosa (AXPC1).

General readings

Friedman J.S., et al. (2002) Hum. Mol. Genet. 11:1333-1342

3 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Opticin antibody

  Rabbit Polyclonal Anti-OPTC Antibody  
WB Suggested Anti-OPTC Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 12500; Positive Control: Human heart Rabbit IgG Purified Can, Eq, Hu, Ms, Por, Rb, Rt WB
50 µg / €360.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Opticin (20-332, His-tag)

Opticin Human Purified > 85 % by SDS - PAGE E. coli
0.5 mg / €730.00
  OriGene Technologies GmbH

Opticin (20-332, His-tag)

Opticin Human Purified > 85 % by SDS - PAGE E. coli
0.1 mg / €300.00
  OriGene Technologies GmbH

3 Item(s)

per page
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