ORAI2 antibody

Principal name

ORAI2 antibody

Alternative names for ORAI2 antibody

Protein orai-2, C7orf19, CBCIP2, TMEM142B, Transmembrane protein 142B, CAP-binding protein complex-interacting protein 2

SwissProt ID

Q5ZLW2 (Chick), Q8BH10 (Mouse), Q96SN7 (Human)

Gene ID

80228 (ORAI2), 269717 (Orai2)

Available reactivities

Hu (Human), Ms (Mouse), Bov (Bovine), Can (Canine), Rt (Rat), Rb (Rabbit)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Enzyme Immunoassay (E)

Background of ORAI2 antibody

Cytosolic Ca2+ has long been known to act as a key second messenger in many intracellular pathways including syptic transmission, muscle contraction, hormol secretion, and cell growth and proliferation. The mechanism controlling intracellular Ca2+ level influx, either by the calcium-release-activated Ca2+ channels (CRAC) or from intracellular stores, has become of great interest. Recently, several key players of the store-operated complex have been identified: the Orai family consisting of three members, Orai1-3, and the STIM family, which consists of two members, STIM1 and STIM2. Orai1 (also known as CRACM1) acts as the store-operated calcium channel (SOC) and STIM1 as the endoplasmic reticulum Ca2+ sensor. Orai1, Orai2, and Orai3 are all capable of forming store-operated channels. Co-expresssion of Orai2 and STIM1 was shown to produce currents that appear similar but smaller than those produced by co-expression of Orai1 and STIM1. Orai2 transcripts are predomintly expressed in kidney, lung, and spleen, and it appears that Orai2 is the only Orai isoform with multiple transcripts.

General readings

DeHaven,W.I., (2007) J. Biol. Chem. 282 (24), 17548-17556

17 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ORAI2 (C-term) antibody

  Rabbit Polyclonal ORAI2 Antibody  
Western blot analysis of ORAI2 in Jurkat cell lysate with ORAI2 antibody at (A) 1, (B) 2 and (C) 4 ug/mL. Rabbit IgG Aff - Purified Hu, Ms E, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

ORAI2 antibody

  Rabbit Polyclonal Anti-Orai2  
Western blot analysis of HL-60 (lanes 1 and 3) and Jurkat (lanes 2 and 4) cell lysates: 1, 2. Anti-Orai2 antibody, (1:200). 3, 4. Anti-Orai2 antibody, preincubated with the control peptide antigen. Rabbit Purified Hu, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

ORAI2 antibody

  Rabbit Polyclonal Anti-ORAI2 Antibody  
WB Suggested Anti-ORAI2 Antibody Titration: 0.2-1 ug/ml; Positive Control: MCF7 cell lysate Rabbit IgG Purified Bov, Can, Hu, Rb WB
50 µg / €325.00
  OriGene Technologies, Inc.

ORAI2 antibody

  ORAI2 mouse monoclonal antibody, clone OTI8D11 (formerly 8D11)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ORAI2 (RC221137, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ORAI2.(1:500) Mouse IgG2b OTI8D11 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

ORAI2 antibody

Placenta: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit IgG Aff - Purified Hu, Ms P, WB
50 µg / €470.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

ORAI2 - human gene knockout kit via CRISPR

ORAI2 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

ORAI2 - human gene knockout kit via CRISPR

ORAI2 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

ORAI2 - human gene knockout kit via CRISPR

ORAI2 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

ORAI2 - human gene knockout kit via CRISPR

ORAI2 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Orai2 - mouse gene knockout kit via CRISPR

Orai2 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Orai2 - mouse gene knockout kit via CRISPR

Orai2 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Orai2 - mouse gene knockout kit via CRISPR

Orai2 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Orai2 - mouse gene knockout kit via CRISPR

Orai2 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

ORAI2 overexpression lysate

ORAI2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

ORAI2 overexpression lysate

ORAI2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, ORAI2 (mGFP-tagged) - Human ORAI calcium release-activated calcium modulator 2 (ORAI2), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, ORAI2 (mGFP-tagged) - Human ORAI calcium release-activated calcium modulator 2 (ORAI2), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, ORAI2 (Myc-DDK tagged) - Human ORAI calcium release-activated calcium modulator 2 (ORAI2), transcript variant 1 , 200 uL, >10^7 TU/mL

Lenti ORF particles, ORAI2 (Myc-DDK tagged) - Human ORAI calcium release-activated calcium modulator 2 (ORAI2), transcript variant 1 , 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

17 Item(s)

per page
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