OS9 antibody

Principal name

OS9 antibody

Alternative names for OS9 antibody

Amplified in osteosarcoma 9, OS-9

SwissProt ID

Q13438 (Human), Q3MHX6 (Bovin), Q99220 (Yeast)

Gene ID

10956 (OS9)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), Rb (Rabbit)

Available hosts

Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Western blot / Immunoblot (WB), Immunoprecipitation (IP), ELISA (detection) (E(detection)), Frozen Sections (C)

Background of OS9 antibody

OS9 (protein OS-9 or amplified in osteosarcoma 9) is a lectin/glycoprotein that functions in ER quality control and ER-associated degradation (ERAD pathway) of newly synthesized proteins. TRPV4 is its major target and OS9 also interact with GRP94, DERL2, HSP90B1, CREB3, ERLEC1, HSPA5 etc., forms a part of HRD1 ubiquitin ligase complex (SYVN1/HRD1 and SEL1L) which is involved in retrotranslocation of misfolded proteins from ER to cytosol for ubiquitin dependent degradation. OS9 is essential for recognizition of termilly misfolded non-glycosylated proteins or improperly folded glycoproteins, binding with them for their retention in ER, and transferring them to ubiquitition machinery for degradation. Moreover, it has also been shown to specifically protect some proteins from degradation process before maturation, ensuring their biological functiolity. Because OS9 is implicated in protein quality control, it is closely related to ER stress, and gets up-regulated in response to ER stress. Recently, it has been shown to highly express in adipocytes wherein it regulated lipid storage, and its overexpression is also observed in sarcomas especially in osteosarcoma OSA-CL and rhabdomyosarcoma RH30 cell lines.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

OS9 antibody

Detection of OS-9.1 and OS-9.2 in total HEK293 cells, HEK293 cells expressing OS-9.1 or OS-9.2 by western analysis. Rabbit IgG Purified Hu, Ms WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

OS9 antibody

Host: Rabbit; Target Name: OS9; Sample Tissue: Lung Tumor lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Bov, Can, Eq, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

OS9 antibody

Western Blot: OS9 Antibody [TA336257] - WB analysis of OS9 in 1. A431 cell lysate, 2. HepG2 cell lysate, 3. MCF7 cell lysate and 4. 3T3 cell lysate. Rabbit Purified Hu, Ms, Rt ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

OS9 antibody

OS9 MaxPab polyclonal antibody. Western Blot analysis of OS9 expression in human kidney. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

OS9 antibody

OS9 Mouse Hu WB
50 µg / €370.00
  Abnova Taiwan Corp.

OS9 antibody

Western blot analysis of OS9 in lysates of 293 cells expressing OS-9.1 and OS-9.2 with OS9 polyclonal antibody ( Cat# PAB12082 ). Rabbit Hu, Ms C, ICC/IF, IP, P, WB
0.1 ml / €470.00
  Abnova Taiwan Corp.

OS9 Control Peptide

OS9
50 µg / €140.00
  Novus Biologicals Inc.

OS9 antibody

OS9 Rabbit Purified Hu, Ms, Rt ICC/IF, WB
25 µl / €160.00
  Novus Biologicals Inc.

OS9 antibody

OS9 Rabbit Biotin Hu, Ms ICC/IF, IP, P, WB
0.1 ml / €360.00
  Novus Biologicals Inc.

OS9 antibody

OS9 Rabbit DyLight488 Hu, Ms ICC/IF, IP, P, WB
0.1 ml / €390.00
  Novus Biologicals Inc.

OS9 antibody

OS9 Rabbit HRP Hu, Ms ICC/IF, IP, P, WB
0.1 ml / €390.00
  Novus Biologicals Inc.

OS9 Control Peptide

OS9
50 µg / €140.00
  Novus Biologicals Inc.

OS9 antibody

OS9 Rabbit Aff - Purified Hu, Ms ICC/IF, IP, P, WB
25 µl / €200.00
  Novus Biologicals Inc.

OS9 antibody

Immunohistochemistry-Paraffin: OS9 Antibody [NBP1-84803] - Immunohistochemistry-Paraffin: OS9 Antibody [NBP1-84803] Immunohistochemical staining of human testis shows strong positivity in spermatogenic cells. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

OS9 (transcript variant 4)

OS9 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

OS9 (transcript variant 1)

OS9 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

OS9

OS9 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

OS9

OS9 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

OS9 293T Cell Transient Overexpression Lysate(Denatured)

OS9 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

OS9 overexpression lysate

OS9 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

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