OS9 antibody

Principal name

OS9 antibody

Alternative names for OS9 antibody

Amplified in osteosarcoma 9, OS-9

SwissProt ID

Q13438 (Human), Q3MHX6 (Bovin), Q99220 (Yeast)

Gene ID

10956 (OS9)

Available reactivities

Hu (Human), Ms (Mouse), Bov (Bovine), Can (Canine), Eq (Equine), Rb (Rabbit), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Paraffin Sections (P), Enzyme Immunoassay (E)

Background of OS9 antibody

OS9 (protein OS-9 or amplified in osteosarcoma 9) is a lectin/glycoprotein that functions in ER quality control and ER-associated degradation (ERAD pathway) of newly synthesized proteins. TRPV4 is its major target and OS9 also interact with GRP94, DERL2, HSP90B1, CREB3, ERLEC1, HSPA5 etc., forms a part of HRD1 ubiquitin ligase complex (SYVN1/HRD1 and SEL1L) which is involved in retrotranslocation of misfolded proteins from ER to cytosol for ubiquitin dependent degradation. OS9 is essential for recognizition of termilly misfolded non-glycosylated proteins or improperly folded glycoproteins, binding with them for their retention in ER, and transferring them to ubiquitition machinery for degradation. Moreover, it has also been shown to specifically protect some proteins from degradation process before maturation, ensuring their biological functiolity. Because OS9 is implicated in protein quality control, it is closely related to ER stress, and gets up-regulated in response to ER stress. Recently, it has been shown to highly express in adipocytes wherein it regulated lipid storage, and its overexpression is also observed in sarcomas especially in osteosarcoma OSA-CL and rhabdomyosarcoma RH30 cell lines.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

OS9 antibody

  Rabbit Polyclonal Antibody against OS-9  
Detection of OS-9.1 and OS-9.2 in total HEK293 cells, HEK293 cells expressing OS-9.1 or OS-9.2 by western analysis. Rabbit IgG Purified Hu, Ms WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

OS9 antibody

  Rabbit Polyclonal Anti-OS9 Antibody  
Host: Rabbit; Target Name: OS9; Sample Tissue: Lung Tumor lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Bov, Can, Eq, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

OS9 antibody

  Rabbit Polyclonal OS9 Antibody  
Western Blot: OS9 Antibody [TA336257] - WB analysis of OS9 in 1. A431 cell lysate, 2. HepG2 cell lysate, 3. MCF7 cell lysate and 4. 3T3 cell lysate. Rabbit Purified Hu, Ms, Rt ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

OS9 antibody

  Rabbit Polyclonal Anti-OS9 Antibody  
OS9 Rabbit IgG Purified Hu, Ms E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CRISPR

Catalog No. Species Donor Vector  

OS9 - human gene knockout kit via CRISPR

OS9 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

OS9 - human gene knockout kit via CRISPR

OS9 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

OS9 - human gene knockout kit via CRISPR

OS9 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

OS9 - human gene knockout kit via CRISPR

OS9 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

OS9 (transcript variant 4)

  Recombinant protein of human osteosarcoma amplified 9, endoplasmic reticulum associated protein (OS9), transcript variant 4  
OS9 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

OS9 (transcript variant 1)

  Recombinant protein of human osteosarcoma amplified 9, endoplasmic reticulum associated protein (OS9), transcript variant 1  
OS9 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

OS9 overexpression lysate

OS9 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, OS9 (mGFP-tagged) - Human osteosarcoma amplified 9, endoplasmic reticulum lectin (OS9), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, OS9 (mGFP-tagged) - Human osteosarcoma amplified 9, endoplasmic reticulum lectin (OS9), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,510.00
  OriGene Technologies, Inc.

Lenti ORF particles, OS9 (mGFP-tagged)-Human osteosarcoma amplified 9, endoplasmic reticulum lectin (OS9), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, OS9 (mGFP-tagged)-Human osteosarcoma amplified 9, endoplasmic reticulum lectin (OS9), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, OS9 (mGFP-tagged)-Human osteosarcoma amplified 9, endoplasmic reticulum lectin (OS9), transcript variant 3, 200 uL, >10^7 TU/mL

Lenti ORF particles, OS9 (mGFP-tagged)-Human osteosarcoma amplified 9, endoplasmic reticulum lectin (OS9), transcript variant 3, 200 uL, >10^7 TU/mL  
200 µl / €1,250.00
  OriGene Technologies, Inc.

Lenti ORF particles, OS9 (Myc-DDK tagged) - Human osteosarcoma amplified 9, endoplasmic reticulum lectin (OS9), transcript variant 1 , 200 uL, >10^7 TU/mL

Lenti ORF particles, OS9 (Myc-DDK tagged) - Human osteosarcoma amplified 9, endoplasmic reticulum lectin (OS9), transcript variant 1 , 200 uL, >10^7 TU/mL  
200 µl / €1,360.00
  OriGene Technologies, Inc.

Lenti ORF particles, OS9 (Myc-DDK-tagged)-Human osteosarcoma amplified 9, endoplasmic reticulum lectin (OS9), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, OS9 (Myc-DDK-tagged)-Human osteosarcoma amplified 9, endoplasmic reticulum lectin (OS9), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Lenti ORF particles, OS9 (Myc-DDK-tagged)-Human osteosarcoma amplified 9, endoplasmic reticulum lectin (OS9), transcript variant 3, 200 uL, >10^7 TU/mL

Lenti ORF particles, OS9 (Myc-DDK-tagged)-Human osteosarcoma amplified 9, endoplasmic reticulum lectin (OS9), transcript variant 3, 200 uL, >10^7 TU/mL  
200 µl / €1,120.00
  OriGene Technologies, Inc.

17 Item(s)

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