OSBP antibody

Principal name

OSBP antibody

Alternative names for OSBP antibody

OSBP1, OSBP-1, Oxysterol-binding protein 1

SwissProt ID

P16258 (Rabit), P22059 (Human), Q3B7Z2 (Mouse)

Gene ID

5007 (OSBP), 76303 (Osbp)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Can (Canine), Chimp (Chimpanzee), Rb (Rabbit), Bov (Bovine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Ze (Zebrafish)

Available hosts

Goat, Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Flow Cytometry (F), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of OSBP antibody

OSBP (Oxysterol-Binding Protein), also called OSBP1, is a protein that in humans is encoded by the OSBP gene. Im et al. (2005) reported the structure of the full-length yeast oxysterol-binding-protein Osh4, a member of the OSBP-related protein (ORP) family, at 1.5- to 1.9-angstrom resolution in complexes with ergosterol, cholesterol, and 7-, 20- and 25-hydroxy cholesterol. Moreira et al. (2001) refined the localization of the OSBP1 gene to chromosome 11q12.1 by radiation hybrid analysis. Wang et al. (2005) found that OSBP functions as a cholesterol-binding scaffolding protein coordinating the activity of 2 phosphatases to control the extracellular signal-regulated kinase (ERK) signaling pathway. Cytosolic OSBP formed an approximately 440-kD oligomer with a member of the PTPPBS family of tyrosine phosphatases, the serine/threonine phosphatase PP2A, and cholesterol.

General readings

Moreira EF, Jaworski C, Li A, Rodriguez IR.
Molecular and biochemical characterization of a novel oxysterol-binding protein (OSBP2) highly expressed in retina.
J Biol Chem. 2001 May 25;276(21):18570-8. Epub 2001 Jan 26.
PMID: 11278871

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

OSBP antibody

  OSBP mouse monoclonal antibody, clone OTI1F2 (formerly 1F2)  
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-OSBP mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA503140) Mouse IgG1 OTI1F2 Purified Hu F, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

OSBP antibody

  OSBP mouse monoclonal antibody, clone OTI1A4 (formerly 1A4)  
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-OSBP mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA503180) Mouse IgG1 OTI1A4 Purified Hu P, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

OSBP antibody

  Goat Polyclonal Antibody against OSBP  
TA303012 (0.1µg/ml) staining of Human Placenta lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Can, Chimp, Hu, Ms, Rb, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

OSBP (C-term) antibody

  Goat Anti-OSBP1 (C Terminus) Antibody  
TA305774 (2ug/ml) staining of Human Liver lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

OSBP antibody

  Rabbit Polyclonal Anti-OSBP Antibody  
WB Suggested Anti-OSBP Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: Human Muscle Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

OSBP antibody

OSBP Mouse IgG2a 5A3 Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

OSBP antibody

OSBP Goat Hu E
0.1 mg / €400.00
  Abnova Taiwan Corp.

OSBP antibody

OSBP polyclonal antibody ( Cat # PAB6769 ) ( 0.1 µg/ml ) staining of human placenta lysate ( 35 µg protein in RIPA buffer ) . Primary incubation was 1 hour. Detected by chemiluminescence. Goat Hu E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

OSBP (C-term) antibody

Human Muscle; WB Suggested Anti-OSBP Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: Human Muscle; OSBP antibody - C-terminal region (ARP60212_P050) in Human Muscle cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

OSBP antibody

OSBP Rabbit IgG Aff - Purified Hu, Ms, Rt WB
0.1 mg / €290.00
  Boster Immunoleader

CRISPR

Catalog No. Species Donor Vector  

OSBP - human gene knockout kit via CRISPR

OSBP - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

OSBP - human gene knockout kit via CRISPR

OSBP - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

OSBP - human gene knockout kit via CRISPR

OSBP - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

OSBP - human gene knockout kit via CRISPR

OSBP - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Osbp - mouse gene knockout kit via CRISPR

Osbp - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Osbp - mouse gene knockout kit via CRISPR

Osbp - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Osbp - mouse gene knockout kit via CRISPR

Osbp - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Osbp - mouse gene knockout kit via CRISPR

Osbp - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

OSBP

  Recombinant protein of human oxysterol binding protein (OSBP)  
OSBP Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

OSBP

OSBP Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

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