Osteocalcin antibody

Principal name

Osteocalcin antibody

Alternative names for Osteocalcin antibody

Bone Gla protein, BGLAP, Gamma-carboxyglutamic acid-containing protein

SwissProt ID

P02818 (Human), P02820 (Bovin), P02821 (Felca), P02822 (Chick), P04640 (Rat), P04641 (Mouse), P40147 (Xenla), Q8HYY9 (Pig)

Gene ID

632 (BGLAP), 12097 (Bglap2), 281646, 25295 (Bglap)

Available reactivities

Bov (Bovine), Can (Canine), Elk, Hu (Human), Mky (Monkey), Ms (Mouse), Por (Porcine), Rb (Rabbit), Rt (Rat)

Available hosts

Rabbit, Goat, Mouse

Available applications

Frozen Sections (C), Flow Cytometry (F), Immunocytochemistry/Immunofluorescence (ICC/IF), Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Radioimmunoassay (R), ELISA (capture) (E(capture)), ELISA (detection) (E(detection)), Paraffin Sections (P)

Background of Osteocalcin antibody

Prior to the formation of calcified bone, noncollagenous proteins form in the extracellular bone matrix. Gamma-carboxyglutamic acid residues are formed by vitamin K, vitamin-D regulated calcium binding proteins containing residues of Gla. These residues are essential for the binding of calcium and constitue 1-2% of total bone protein. Osteocalcin itself binds strongly to apatite and calcium. Production of osteocalcin is expressed late in normal bone development and is characteristic of mature osteoblasts. Regular osteocalcin production has been shown to be linked to the p53 tumor suppressor gene. The p53 gene undergoes rearrangement in a high percentage of osteosarcomas, resulting in loss of its expression. The loss of p53 regulation inhibits further osteocalcin production. The absence of end-point differentiation in bone due to p53 rearrangements and lack of osteocalcin production may contribute to the maintenance of the tumorigenic phenotype in osteosarcomas.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Osteocalcin antibody

  Anti-BGLAP Rabbit Polyclonal Antibody  
Predicted cell location: Cytoplasm. Positive control: Human breast and ovarian cancer tissue . Recommended dilution: 1/50-200  The image on the left is immunohistochemistry of paraffin-embedded human breast cancer tissue using BGLAP antibody at dilution 1/60, on the right is treated with the synthetic peptide. (Original magnification:x 200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Osteocalcin antibody

  Anti-BGLAP Rabbit Polyclonal Antibody  
Predicted cell location: Cytoplasm. Positive control: Human ovarian and lung cancer tissue . Recommended dilution: 1/25-100  The image on the left is immunohistochemistry of paraffin-embedded human ovarian cancer tissue using BGLAP antibody at dilution 1/30, on the right is treated with the synthetic peptide. (Original magnification:x 200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Osteocalcin antibody

  Rabbit Polyclonal Anti-BGLAP Antibody  
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using (BGLAP Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200) Rabbit IgG Purified Hu E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Osteocalcin antibody

Osteocalcin Mouse IgG1 3G8E1F11 Purified Bov, Hu E
0.2 mg / €330.00
  Acris Antibodies GmbH

Osteocalcin antibody

Osteocalcin Mouse IgG2a 2H9F11F8 Purified Bov, Hu, Por, Rb, Rt E
0.2 mg / €320.00
  Acris Antibodies GmbH

Osteocalcin antibody

Osteocalcin Mouse IgG1 6F9G4E10 Purified Hu E
0.2 mg / €330.00
  Acris Antibodies GmbH

Osteocalcin antibody

Osteocalcin Mouse IgG1 8H12F9H10 Purified Bov, Hu, Por, Rb, Rt E
0.2 mg / €340.00
  Acris Antibodies GmbH

Osteocalcin antibody

Osteocalcin Mouse IgG2a 3H8H12D2A12F12 Purified Bov, Hu, Por, Rb, Rt E
0.2 mg / €320.00
  Acris Antibodies GmbH

Osteocalcin (1-22) antibody

Osteocalcin Rabbit Serum Hu E, R
0.1 ml / €380.00
  Acris Antibodies GmbH

Osteocalcin (1-22) antibody

Osteocalcin Rabbit Serum Hu E, R
20 µl / €150.00
  Acris Antibodies GmbH

Osteocalcin antibody

Osteocalcin Rabbit IgG Purified Hu E, WB
1 ml / €390.00
  Acris Antibodies GmbH

Osteocalcin (N-term) antibody

Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Ig Purified Hu P, WB

Regular Price: 0.4 ml / €370.00

Special Price: 0.4 ml / €231.00

  Acris Antibodies GmbH

Osteocalcin (C-term)/(C-term C80) antibody

BGLAP Antibody (C80) (Cat. #AP50371PU-N) western blot analysis in HepG2 cell line lysates (35µg/lane).This demonstrates the BGLAP antibody detected the BGLAP protein (arrow). Rabbit Ig Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Osteocalcin antibody

Osteocalcin Rabbit Serum Bov, Can, Elk, Hu, Mky C
0.25 ml / €480.00
  Acris Antibodies GmbH

Osteocalcin antibody

Osteocalcin Rabbit Serum Bov, Can, Hu, Mky C, F
0.25 ml / €650.00
  Acris Antibodies GmbH

Osteocalcin antibody

Osteocalcin Goat Serum Ms C, ICC/IF
0.1 ml / €330.00
  Acris Antibodies GmbH

Osteocalcin antibody

Osteocalcin Mouse IgG1 1C4 Purified Bov, Hu E
1 mg / €430.00
  HyTest Ltd.

Osteocalcin antibody

Osteocalcin Mouse IgG1 1C7 Purified Bov, Hu E
1 mg / €430.00
  HyTest Ltd.

Osteocalcin antibody

Osteocalcin Mouse IgG2a 2H9 Purified Bov, Hu E, E(detection)
1 mg / €430.00
  HyTest Ltd.

Osteocalcin antibody

Osteocalcin Mouse IgG2b 3G7 Purified Bov, Hu E
1 mg / €430.00
  HyTest Ltd.

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