OTULIN / FAM105B antibody

Principal name

OTULIN / FAM105B antibody

Alternative names for OTULIN / FAM105B antibody

Deubiquitinating enzyme otulin, OTU domain-containing deubiquitinase with linear linkage specificity, Ubiquitin thioesterase Gumby

Gene ID

90268 (FAM105B)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Eq (Equine), Ms (Mouse), Por (Porcine), Rb (Rabbit), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Western blot / Immunoblot (WB)

Background of OTULIN / FAM105B antibody

FAM105B is a deubiquitise that specifically removes linear ('M-1'-linked) polyubiquitin chains to substrates and acts as a regulator of angiogenesis. It associates with the LUBAC complex via direct interaction with RNF31 and counteracts its action by cleaving linear polyubiquitin chains to substrates. It is required during angiogenesis, craniofacial and neurol development by regulating the canonical Wnt sigling together with the LUBAC complex. FAM105B acts as a negative regulator of NF-kappa-B by counteracting activity of the LUBAC complex

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

OTULIN / FAM105B antibody

Host: Rabbit; Target Name: FAM105B; Sample Tissue: 721_B Whole cell lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Bov, Can, Eq, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

OTULIN / FAM105B antibody

OTULIN / FAM105B Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

OTULIN overexpression lysate

OTULIN overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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