OXSR1 / OSR1 antibody

Principal name

OXSR1 / OSR1 antibody

Alternative names for OXSR1 / OSR1 antibody

Serine/threonine-protein kinase OSR1, KIAA1101, Oxidative stress-responsive 1 protein

SwissProt ID

O95747 (Human), Q6P9R2 (Mouse), Q863I2 (Pig)

Gene ID

9943 (OXSR1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Can (Canine), Mky (Monkey), Bov (Bovine)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunoprecipitation (IP), EPair for Elisa (EPair), Frozen Sections (C), Flow Cytometry (F)

Background of OXSR1 / OSR1 antibody

OXSR1 is a serine/threonine kinase which regulates downstream kinases in response to environmental stress such as osmotic stresses, notably sorbitol and, to a lesser extent, NaCl. OXSR1 phosphorylated thr84 within the N-terminal regulatory domain of PAK1. Replacement of thr84 with gln reduced activation of PAK1 by an active form of the small G protein CDC42, suggesting that phosphorylation by OXSR1 modulates the G protein sensitivity of PAK. OXSR1 interacts with chloride channel proteins SLC12A6 isoform 2, SLC12A1 and SLC12A2 but not with SLC12A4 and SLC12A7, possibly establishing sensor/signaling modules that initiate the cellular response to environmental stress. Binds to and phosphorylates RELL1, RELL2 AND RELT. OXSR1 may have a role in regulating the actin cytoskeleton.

General readings

Nakamura T.Y., et al, (2001) Proc. Natl. Acad. Sci. U.S.A. 98:12808-12813.Bahi N., et al, (2003) Hum. Mol. Genet. 12:1415-1425.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

OXSR1 / OSR1 antibody

Immunohistochemical staining of paraffin-embedded Human liver tissue within the normal limits using anti-OXSR1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500392) Mouse IgG1 OTI1F3 Purified Can, Hu, Mky, Rt F, P, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

OXSR1 / OSR1 antibody

Immunoperoxidase of monoclonal antibody to OXSR1 on formalin-fixed paraffin-embedded human salivary gland. [antibody concentration 3 ug/ml] Mouse IgG2a 3A8 Purified Hu, Ms, Rt E, ICC/IF, P, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

OXSR1 / OSR1 antibody

Immunoperoxidase of monoclonal antibody to OXSR1 on formalin-fixed paraffin-embedded human small Intestine. [antibody concentration 3 ug/ml] Mouse IgG2a 1B9 Purified Hu E, ICC/IF, P, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

OXSR1 / OSR1 antibody

OXSR1 monoclonal antibody (M20), clone 2A5. Western Blot analysis of OXSR1 expression in NIH/3T3 ( Cat # L018V1 ). Mouse IgG2a 2A5 Purified Hu, Ms, Rt E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

OXSR1 / OSR1 antibody

Sample (30 ug of whole cell lysate). A: 293T. 7.5% SDS PAGE. TA308621 diluted at 1:10000. Rabbit IgG Aff - Purified Hu ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

OXSR1 / OSR1 antibody

Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue using OSR1 antibody.The picture on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

OXSR1 / OSR1 pThr185 antibody

Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using OSR1 (Phospho-Thr185) antibody AP55768PU-N (left)or the same antibody preincubated with blocking peptide (right). Rabbit Aff - Purified Hu, Ms P, WB
0.1 ml / €340.00
  Acris Antibodies GmbH

OXSR1 / OSR1 pThr185 antibody

Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using OSR1 (Phospho-Thr185) antibody AP55768PU-N (left)or the same antibody preincubated with blocking peptide (right). Rabbit Aff - Purified Hu, Ms P, WB
50 µl / €270.00
  Acris Antibodies GmbH

OXSR1 / OSR1 antibody

OXSR1 / OSR1 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

OXSR1 / OSR1 antibody

Immunofluorescence of purified MaxPab antibody to OXSR1 on HeLa cell. [antibody concentration 10 ug/ml] Mouse Serum Hu E(detection), ICC/IF, WB
50 µl / €370.00
  Abnova Taiwan Corp.

OXSR1 / OSR1 antibody

Western Blot analysis of OXSR1 expression in transfected 293T cell line (H00009943-T03) by OXSR1 MaxPab polyclonal antibody.

Lane 1: OXSR1 transfected lysate(58.00 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

OXSR1 / OSR1 antibody

Immunofluorescence of monoclonal antibody to OXSR1 on HeLa cell. [antibody concentration 10 ug/ml] Mouse IgG1 2A2-1A2 Purified Hu E, ICC/IF, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

OXSR1 / OSR1 antibody

OXSR1 / OSR1 Mouse IgG1 S1 Hu E, WB
0.2 ml / €370.00
  Abnova Taiwan Corp.

OXSR1 / OSR1 antibody

Immunoperoxidase of monoclonal antibody to OXSR1 on formalin-fixed paraffin-embedded human testis. [antibody concentration 3 ug/ml] Mouse IgG2a 1D10 Purified Hu E, P
0.1 mg / €370.00
  Abnova Taiwan Corp.

OXSR1 / OSR1 antibody

Immunoperoxidase of monoclonal antibody to OXSR1 on formalin-fixed paraffin-embedded human stomach. [antibody concentration 3 ug/ml] Mouse IgG2a 6C7 Purified Hu E, P, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

OXSR1 / OSR1 antibody

Immunoperoxidase of monoclonal antibody to OXSR1 on formalin-fixed paraffin-embedded human small Intestine. [antibody concentration 3 ug/ml] Mouse IgG2a 4G9 Purified Hu E, P, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

OXSR1 / OSR1 antibody

OXSR1 / OSR1 Mouse IgG2a 5E1 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

OXSR1 / OSR1 antibody

OXSR1 monoclonal antibody (M06), clone 1C8 Western Blot analysis of OXSR1 expression in HeLa ( Cat # L013V1 ). Mouse IgG3 1C8 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

OXSR1 / OSR1 antibody

OXSR1 / OSR1 Mouse IgG3 1C8 Hu E, WB
0.2 ml / €370.00
  Abnova Taiwan Corp.

OXSR1 / OSR1 antibody

OXSR1 / OSR1 Mouse IgG3 1C8 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

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