P2RX1 / P2X1 antibody

Principal name

P2RX1 / P2X1 antibody

Alternative names for P2RX1 / P2X1 antibody

P2X purinoceptor, Purinergic receptor, ATP receptor

SwissProt ID

P47824 (Rat), P51575 (Human), P51576 (Mouse)

Gene ID

5023 (P2RX1), 25505 (P2rx1)

Available reactivities

Rt (Rat), Hu (Human), Ms (Mouse), Bov (Bovine), Can (Canine), Por (Porcine), Mky (Monkey), Rb (Rabbit), Eq (Equine), GP (Guinea Pig)

Available hosts

Rabbit

Available applications

Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Western blot / Immunoblot (WB), ELISA (detection) (E(detection))

Background of P2RX1 / P2X1 antibody

P2RX1 belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel with relatively high calcium permeability. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle, being responsible, for example, for sympathetic vasoconstriction in small arteries, arterioles and vas deferens. Mouse studies suggest that this receptor is essential for normal male reproductive function. It is possible that the development of selective antagonists for this receptor may provide an effective non-hormonal male contraceptive pill.The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel with relatively high calcium permeability. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle, being responsible, for example, for sympathetic vasoconstriction in small arteries, arterioles and vas deferens. Mouse studies suggest that this receptor is essential for normal male reproductive function. It is possible that the development of selective antagonists for this receptor may provide an effective non-hormonal male contraceptive pill.

General readings

General / background references:Vulchanova L et al. Differential distribution of two ATP-gated channels (P2X receptors) determined by immunocytochemistry. Proc Natl Acad Sci U S A 93:8063-7 (1996). PubMed PMID: 8755603
Valera S et al. A new class of ligand-gated ion channel defined by P2x receptor for extracellular ATP. Nature 371:516-9 (1994). PubMed PMID: 7523951

12 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

P2RX1 / P2X1 antibody

Western blot analysis of human platelet lysates: 1. Anti-P2X1 Receptor antibody , (1:200). 2. Anti-P2X1 Receptor antibody, preincubated with the control peptide antigen. Rabbit Purified Hu, Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

P2RX1 / P2X1 antibody

Western blot analysis of rat brain (lanes 1 and 3) and mouse brain (lanes 2 and 4) lysates: 1, 2. Anti-P2X1 Receptor (extracellular) antibody , (1:200). 3, 4. Anti-P2X1 Receptor (extracellular) antibody, preincubated with the control peptide antigen. Rabbit Purified Hu, Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

P2RX1 / P2X1 antibody

WB Suggested Anti-P2RX1 Antibody Titration: 2.5 ug/ml; ELISA Titer: 1:312500; Positive Control: HepG2 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

P2RX1 / P2X1 antibody

P2RX1 / P2X1 Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

P2RX1 / P2X1 antibody

Human Pancreas; P2RX1 antibody - middle region (ARP35105_T100) in Human Pancreas cells using Immunohistochemistry Rabbit Aff - Purified Bov, Can, Hu, Ms, Por, Rt P, WB
0.1 mg / €310.00
  AVIVA Systems Biology

P2RX1 / P2X1 antibody

Western blot analysis of P2X1 expression in K562 (A); A549 (B); SP2/0 (C); PC12 (D) whole cell lysates. Rabbit Aff - Purified Hu, Mky, Ms, Rb, Rt WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

P2RX1 / P2X1 antibody

Western blot analysis of P2X1 expression in K562 (A); A549 (B); SP2/0 (C); PC12 (D) whole cell lysates. Rabbit Aff - Purified Hu, Mky, Ms, Rb, Rt WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

P2RX1 / P2X1 antibody

Western blot analysis of P2X1 expression in K562 (A); A549 (B); SP2/0 (C); PC12 (D) whole cell lysates. Rabbit Aff - Purified Hu, Mky, Ms, Rb, Rt WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

P2RX1 / P2X1 Control Peptide

P2RX1 / P2X1 Purified
20 µg / €150.00
  Neuromics Antibodies

P2RX1 / P2X1 antibody

P2RX1 / P2X1 Rabbit Serum Rt C, ICC/IF
50 µl / €190.00
  Neuromics Antibodies

P2RX1 / P2X1 antibody

P2RX1 / P2X1 Rabbit Serum Rt C, ICC/IF
0.15 ml / €350.00
  Neuromics Antibodies

P2RX1 / P2X1 antibody

Immunohistochemistry: P2X1 Antibody [NB100-1651] - Vas Deferens Rabbit IgG Serum Rt P
50 µl / €310.00
  Novus Biologicals Inc.

12 Item(s)

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