P2RX2 / P2X2 antibody

Principal name

P2RX2 / P2X2 antibody

Alternative names for P2RX2 / P2X2 antibody

P2X purinoceptor 2, ATP receptor, Purinergic receptor

SwissProt ID

O70397 (Cavpo), P49653 (Rat), Q9UBL9 (Human)

Gene ID

22953 (P2RX2), 1222953 (RSp0646), 114115 (P2rx2)

Available reactivities

Hu (Human), Ms (Mouse), GP (Guinea Pig), Por (Porcine), Prim (Primate), Rt (Rat), Mky (Monkey), Bov (Bovine), Ze (Zebrafish), Can (Canine), Eq (Equine), Rb (Rabbit)

Available hosts

Rabbit, Guinea Pig, Goat, Mouse

Available applications

Paraffin Sections (P), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Frozen Sections (C), Enzyme Immunoassay (E)

Background of P2RX2 / P2X2 antibody

The P2X receptors belong to the ligand-gated ion channel family and are activated by extracellular ATP. The structure and function of the P2X receptors, which were mainly investigated using in vitro models, indicate of their involvement in syptic communication, cell death, and differentiation. Seven mammalian P2X receptor subtypes (P2X1â??P2X7) have been identified and cloned.1,2,3 All P2X receptor subtypes share the same structure of intracellular N and C-termini, two membrane-spanning domains and a large extracellular loop. All P2X subtypes can assemble to form homomeric or heteromeric functiol channels with the exception of P2X6, which only seems to function as part of a heteromeric complex.4-9 The various mammalian P2X receptors show distinct expression patterns. P2X1-6 have been found in the central and peripheral nervous system, while the P2X7 receptor is predomintly found in cells of the immune system.4 The P2X2 receptor subtypes has a widespread tissue distribution in autonomic neurons, but it is generally found to be co-expressed with one or more subtypes. mR of the P2X1, P2X2, P2X3, and P2X6 receptors is found in neurons of dorsal root ganglia (DRG), trigemil, and nodose ganglia where heteromeric P2X2/P2X3 receptors are found.10share the same structure of intracellular N and C-termini, two membrane-spanning domains and a large extracellular loop. All P2X subtypes can assemble to form homomeric or heteromeric functiol channels with the exception of P2X6, which only seems to function as part of a heteromeric complex. The various mammalian P2X receptors show distinct expression patterns. P2X1-6 have been found in the central and peripheral nervous system, while the P2X7 receptor is predomintly found in cells of the immune system. The P2X2 receptor subtypes has a widespread tissue distribution in autonomic neurons, but it is generally found to be co-expressed with one or more subtypes. mR of the P2X1, P2X2, P2X3, and P2X6 receptors is found in neurons of dorsal root ganglia (DRG), trigemil, and nodose ganglia where heteromeric P2X2/P2X3 receptors are found.

General readings

General / background references:Vulchanova L et al. Immunohistochemical study of the P2X2 and P2X3 receptor subunits in rat and monkey sensory neurons and their central terminals. Neuropharmacology 36:1229-42 (1997). PubMed PMID: 9364478
Vulchanova L et al. Differential distribution of two ATP-gated channels (P2X receptors) determined by immunocytochemistry. Proc Natl Acad Sci U S A 93:8063-7 (1996). PubMed PMID: 8755603
Brake AJ et al. New structural motif for ligand-gated ion channels defined by an ionotropic ATP receptor. Nature 371:519-23 (1994). PubMed PMID: 7523952

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

P2RX2 / P2X2 antibody

Western blot analysis of differentiated (lanes 1 and 3) and non-differentiated (lanes 2 and 4) PC12 cell lysates: 1, 2. Anti-P2X2 Receptor antibody , (1:200). 3, 4. Anti-P2X2 Receptor antibody, preincubated with the control peptide antigen. Rabbit Purified Hu, Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

P2RX2 / P2X2 antibody

Western blot analysis of rat brain membrane (lanes 1 and 4), mouse brain membrane (lanes 2 and 5) and PC12 (lanes 3 and 6): 1-3. Anti-P2X2 Receptor (extracellular) antibody , (1:200). 4-6. Anti-P2X2 Receptor (extracellular) antibody, preincubated with the control peptide antigen. Rabbit Purified Ms, Rt WB
50 µl / €325.00
  OriGene Technologies, Inc.

P2RX2 / P2X2 antibody

WB Suggested Anti-P2RX2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:1562500; Positive Control: Jurkat cell lysate Rabbit IgG Purified Can, Eq, Hu, Por, Rb WB
50 µg / €325.00
  OriGene Technologies, Inc.

P2RX2 / P2X2 antibody

WB Suggested Anti-P2RX2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: OVCAR-3 cell lysate P2RX2 is strongly supported by BioGPS gene expression data to be expressed in Human OVCAR3 cells Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

P2RX2 / P2X2 antibody

WB Suggested Anti-P2RX2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:2500; Positive Control: Jurkat cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

P2RX2 / P2X2 antibody

WB Suggested Anti-P2RX2 Antibody Titration: 0.6 ug/ml; ELISA Titer: 1:62500; Positive Control: Jurkat cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

P2RX2 / P2X2 antibody

WB Suggested Anti-P2RX2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: Jurkat cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

P2RX2 / P2X2 antibody

WB Suggested Anti-P2RX2 Antibody Titration: 1.25 ug/ml; ELISA Titer: 1:312500; Positive Control: HepG2 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

P2RX2 / P2X2 antibody

WB Suggested Anti-P2RX2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:1562500; Positive Control: 293T cell lysate Rabbit IgG Purified Bov, GP, Hu, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

P2RX2 / P2X2 antibody

WB Suggested Anti-P2RX2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: 293T cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

P2RX2 / P2X2 antibody

WB Suggested Anti-P2RX2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:1562500; Positive Control: Jurkat cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

P2RX2 / P2X2 antibody

P2RX2 / P2X2 Mouse IgG2a 3D5 Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

P2RX2 / P2X2 antibody

Human Jurkat; WB Suggested Anti-P2RX2 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:1562500. Positive Control: Jurkat cell lysate; P2RX2 antibody - N-terminal region (ARP35208_P050) in Human Jurkat cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

P2RX2 / P2X2 antibody

Human OVCAR3; WB Suggested Anti-P2RX2 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: OVCAR-3 cell lysate. P2RX2 is strongly supported by BioGPS gene expression data to be expressed in Human OVCAR3 cells.; P2RX2 antibody - N-terminal region (ARP35209_P050) in Human OVCAR3 cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

P2RX2 / P2X2 antibody

Human Jurkat; WB Suggested Anti-P2RX2 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:2500. Positive Control: Jurkat cell lysate; P2RX2 antibody - N-terminal region (ARP35258_P050) in Human Jurkat cells using Western Blot Rabbit Aff - Purified Bov, Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

P2RX2 / P2X2 antibody

Human kidney; P2RX2 antibody - middle region (ARP35259_T100) in Human kidney cells using Immunohistochemistry Rabbit Aff - Purified Bov, Hu P, WB
0.1 mg / €310.00
  AVIVA Systems Biology

P2RX2 / P2X2 antibody

Human Jurkat; WB Suggested Anti-P2RX2 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: Jurkat cell lysate; P2RX2 antibody - N-terminal region (ARP35434_P050) in Human Jurkat cells using Western Blot Rabbit Aff - Purified Bov, Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

P2RX2 / P2X2 antibody

Human HepG2; WB Suggested Anti-P2RX2 Antibody Titration: 1.25ug/ml. ELISA Titer: 1:312500. Positive Control: HepG2 cell lysate; P2RX2 antibody - N-terminal region (ARP35435_T100) in Human HepG2 cells using Western Blot Rabbit Aff - Purified Bov, Can, Hu, Ms, Rt WB
0.1 mg / €310.00
  AVIVA Systems Biology

P2RX2 / P2X2 antibody

Human 293T; WB Suggested Anti-P2RX2 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:1562500. Positive Control: 293T cell lysate; P2RX2 antibody - N-terminal region (ARP35436_P050) in Human 293T cells using Western Blot Rabbit Aff - Purified Bov, Hu WB
50 µg / €350.00
  AVIVA Systems Biology

P2RX2 / P2X2 antibody

Human 293T; WB Suggested Anti-P2RX2 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: 293T cell lysate; P2RX2 antibody - middle region (ARP35505_P050) in Human 293T cells using Western Blot Rabbit Aff - Purified Bov, Can, Hu, Ms, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

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