P2RX3 / P2X3 antibody

Principal name

P2RX3 / P2X3 antibody

Alternative names for P2RX3 / P2X3 antibody

P2X purinoceptor 3, ATP receptor, Purinergic receptor

SwissProt ID

P49654 (Rat), P56373 (Human), Q3UR32 (Mouse)

Gene ID

81739 (P2rx3), 5024 (P2RX3), 228139

Available reactivities

Rt (Rat), Hu (Human), Mky (Monkey), Prim (Primate), Rb (Rabbit), Gorilla, Ms (Mouse)

Available hosts

Guinea Pig, Rabbit

Available applications

Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P)

Background of P2RX3 / P2X3 antibody

The P2X3 receptor belongs to the ligand-gated ion channel P2X family, that consists of seven receptor subtypes med P2X1-P2X7 and is activated by extracellular ATP. 1,2,3 All P2X subunits, with the exception of P2X6, can assemble to form homomeric or heteromeric functiol channels. The different P2X receptors show distinct expression patterns. P2X1-6 has been found in the central and peripheral nervous system, while the P2X7 receptor is predomintly found in cells of the immune system. The P2X3 receptor is highly expressed on nociceptive sensory neurons in dorsal root ganglia (DRG) as a homomer or as a heteromer (P2X3/P2X2). ATP released from damaged cells activates the P2X3 receptor to initiate nociceptive sigls.6,7 Involvement of ATP in the mechanism of chronic pain has been also suggested. P2X3 receptor is now becoming a possible target for the development of pain therapeutics.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

P2RX3 / P2X3 antibody

Anti-P2RX3 / P2X3 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit IgG Purified Gorilla, Hu, Mky, Rb
50 µg / €345.00
  OriGene Technologies, Inc.

P2RX3 / P2X3 antibody

Western blot analysis of rat DRG lysates: 1. Anti-P2X3 Receptor antibody (APR-016), (1:200). 2. Anti-P2X3 Receptor antibody, preincubated with the control peptide antigen. Rabbit Purified Hu, Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

P2RX3 / P2X3 antibody

Western blot analysis of rat DRG: 1. Anti-P2X3 Receptor (extracellular) antibody , (1:200). 2. Anti-P2X3 Receptor (extracellular) antibody, preincubated with the control peptide antigen. Rabbit Purified Ms, Rt WB
50 µl / €325.00
  OriGene Technologies, Inc.

P2RX3 / P2X3 antibody

Gel: 8%SDS-PAGE, Lysate: 40 ug, Lane 1-2: Human bladder tissue, Human bladder transitional cell carcinoma tissue, Primary antibody: (P2RX3 Antibody) at dilution 1/250, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 minutes Rabbit IgG Purified Hu E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

P2RX3 / P2X3 antibody

P2RX3 / P2X3 Guinea Pig Serum Rt C, ICC/IF, WB
0.1 ml / €390.00
  Neuromics Antibodies

P2RX3 / P2X3 Control Peptide

P2RX3 / P2X3 Liquid
0.1 mg / €150.00
  Neuromics Antibodies

P2RX3 / P2X3 (C-term) antibody

DRG sections double-labeled for ASIC3 (red) and either P2X3 (green, A) or TRPV1 (green, B); double-labeled cells are yellow or orange Rabbit Serum Hu, Mky, Rt C, ICC/IF, WB
50 µl / €200.00
  Neuromics Antibodies

P2RX3 / P2X3 (C-term) antibody

DRG sections double-labeled for ASIC3 (red) and either P2X3 (green, A) or TRPV1 (green, B); double-labeled cells are yellow or orange Rabbit Serum Hu, Mky, Rt C, ICC/IF, WB
0.15 ml / €360.00
  Neuromics Antibodies

P2RX3 / P2X3 (C-term) antibody

P2RX3 / P2X3 Rabbit Aff - Purified Hu, Prim, Rt C, ICC/IF, WB
0.1 ml / €350.00
  Neuromics Antibodies

CRISPR

Catalog No. Species Donor Vector  

P2rx3 - mouse gene knockout kit via CRISPR

P2rx3 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

P2rx3 - mouse gene knockout kit via CRISPR

P2rx3 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

P2rx3 - mouse gene knockout kit via CRISPR

P2rx3 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

P2rx3 - mouse gene knockout kit via CRISPR

P2rx3 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

P2RX3 / P2X3

P2RX3 / P2X3 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

P2RX3 / P2X3

P2RX3 / P2X3 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

P2RX3 / P2X3

P2RX3 / P2X3 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

P2RX3 overexpression lysate

P2RX3 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

17 Item(s)

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