P2RY4 / P2Y4 antibody
Principal name
P2RY4 / P2Y4 antibody
Alternative names for P2RY4 / P2Y4 antibody
P2Y purinoceptor 4, P2P, Purinergic receptor, Uridine nucleotide receptor, UNR, NRU
Ncbi ID
9606, NP_002556.1, NM_002565, NP_113868.1, NM_020621, NM_031680
Available reactivities
Available hosts
Available applications
Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P)
Background of P2RY4 / P2Y4 antibody
The P2Y receptors belong to the G-protein coupled receptors superfamily. P2Y receptors mediate the actions of the extracellular nucleotides (ATP, ADP, UTP and UDP) and regulate several physiologic responses, among them, cardiac function, platelet aggregation and SMC proliferation. The mammalian P2Y family currently includes eight functiol receptors; P2Y1, P2Y2, P2Y4, P2Y6, P2Y11, P2Y12, P2Y13, and the UDP-glucose receptor, now remed P2Y14. The P2Y4-receptor is highly expressed in the placenta and with lower levels at lung and vascular smooth muscle. The human P2Y4 receptor is highly selective to UTP while rat P2Y4 receptor is equally activated by both UTP and ATP and also by other triphosphate nucleotides such as Ap4A. Recently it has been shown that P2Y4 receptor is involved in differentiation and cell death of human neuroblastoma SH-SY5Y cells.
Western blot (WB) analysis of P2Y4 antibody (Cat.-No.: AP01333PU-N) in extracts from HeLa cells.
Western blot analysis of extracts from HeLa cells, using P2RY4 antibody.The lane on the right is treated with the synthesized peptide.
Predicted band size: 41 kDa . Positive control: K562 cell lysate. Recommended dilution: 1/200-1000
Predicted cell location: Cytoplasm, Cell membrane. Positive control: Human lung cancer tissue. Recommended dilution: 1/25-100 The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using P2RY4 antibody at dilution 1/30, on the right is treated with the synthetic peptide. (Original magnification: x200)
Western blot analysis of rat brain membranes: 1. Anti-P2Y4 Receptor antibody , (1:300). 2. Anti-P2Y4 Receptor antibody, preincubated with the control peptide antigen.
Expression of P2Y4 receptor in rat cerebellum. Immunohistochemical staining of rat cerebellum using Anti-P2Y4 Receptor antibody . A. P2Y4 receptor (red) appears in astrocytic processes (arrows). B. In contrast, P2Y4 receptor does not appear in Purkinje neuronal dendrites stained for calbindin D28k (green) in the same brain section. This demonstrates the restriction of P2Y4 receptor to astrocytic fibers.
Host: Rabbit; Target Name: P2RY4; Sample Tissue: Fetal Lung lysates; Antibody Dilution: 1.0ug/ml
Anti-P2RY4 / P2Y4 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-P2RY4 / P2Y4 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-P2RY4 / P2Y4 antibody IHC of human Lymph Node, Hodgkins Lymphoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-P2RY4 / P2Y4 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-P2RY4 / P2Y4 antibody IHC of human Pancreas, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-P2RY4 / P2Y4 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-P2RY4 / P2Y4 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-P2RY4 / P2Y4 antibody IHC of human Lymph Node, Hodgkins Lymphoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-P2RY4 / P2Y4 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| TA340714 | P2RY4 / P2Y4 (Extracell. Dom.) antibody |
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| Rabbit Polyclonal Anti-P2RY4 Antibody (Extracellular Domain) | |||||||
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Rabbit | Aff - Purified | Hu | P |
50 µg /
€400.00
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| OriGene Technologies, Inc. | |||||||
 +2 additional images |
Published recently! |
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| TA340949 | P2RY4 / P2Y4 (Cytopl. Dom.) antibody |
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| Rabbit Polyclonal Anti-P2RY4 Antibody (Cytoplasmic Domain) | |||||||
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Rabbit | Aff - Purified | Hu, Ms, Rt | P |
50 µg /
€400.00
|
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| OriGene Technologies, Inc. | |||||||
| +4 additional images |
Highly validated antibody! |
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| TA314314 | P2RY4 / P2Y4 antibody |
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| Rabbit polyclonal anti-P2RY4 antibody | |||||||
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Rabbit | IgG | Purified | Hu, Ms, Rt | E, WB |
0.1 ml /
€325.00
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|
| OriGene Technologies, Inc. | |||||||
| TA321501 | P2RY4 / P2Y4 antibody |
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| Anti-P2RY4 Rabbit Polyclonal Antibody | |||||||
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Rabbit | IgG | Purified | Hu, Ms, Rt | E, P, WB |
0.1 ml /
€325.00
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|
| OriGene Technologies, Inc. | |||||||
| +1 additional image |
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| TA328996 | P2RY4 / P2Y4 antibody |
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| Rabbit polyclonal Anti-P2Y4 Receptor | |||||||
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Rabbit | Purified | Hu, Ms, Rt | WB |
0.2 ml /
€435.00
|
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| OriGene Technologies, Inc. | |||||||
| +1 additional image |
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| TA332124 | P2RY4 / P2Y4 antibody |
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| Rabbit Polyclonal Anti-P2RY4 Antibody | |||||||
 |
Rabbit | IgG | Purified | Hu, Rt | WB |
50 µg /
€325.00
|
|
| OriGene Technologies, Inc. | |||||||
| TA340790 | P2RY4 / P2Y4 antibody |
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| Rabbit Polyclonal Anti-P2RY4 Antibody (Internal) | |||||||
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Rabbit | Purified | Hu, Mky, Rb |
50 µg /
€400.00
|
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| OriGene Technologies, Inc. | |||||||
| AP01333PU-N | P2RY4 / P2Y4 antibody |
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Rabbit | Aff - Purified | Hu, Ms, Rt | WB |
0.1 mg /
€350.00
|
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| Acris Antibodies GmbH | |||||||
| G708-1 | P2RY4 / P2Y4 antibody |
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Rabbit | Aff - Purified | Hu, Ms, Rt | E, WB |
50 µg /
€230.00
|
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| Assay Biotech | |||||||
| G708-2 | P2RY4 / P2Y4 antibody |
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Rabbit | Aff - Purified | Hu, Ms, Rt | E, WB |
0.1 mg /
€330.00
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| Assay Biotech | |||||||
CRISPR
| Catalog No. | Species | Donor Vector | |
|---|---|---|---|
| KN213891 | P2RY4 - human gene knockout kit via CRISPR |
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Human | GFP-Puro |
1 kit /
€1,200.00
|
| OriGene Technologies, Inc. | |||
| KN213891BN | P2RY4 - human gene knockout kit via CRISPR |
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Human | mBFP-Neo |
1 kit /
€1,290.00
|
| OriGene Technologies, Inc. | |||
| KN213891LP | P2RY4 - human gene knockout kit via CRISPR |
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|
Human | Luciferase-Puro |
1 kit /
€1,290.00
|
| OriGene Technologies, Inc. | |||
| KN213891RB | P2RY4 - human gene knockout kit via CRISPR |
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Human | RFP-BSD |
1 kit /
€1,290.00
|
| OriGene Technologies, Inc. | |||
Lysates
| Catalog No. | ||
|---|---|---|
| LY400911 | P2RY4 overexpression lysate |
|
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0.1 mg /
€280.00
|
|
| OriGene Technologies, Inc. |
Human Lenti ORF Particles
| Catalog No. | ||
|---|---|---|
| RC213891L2V | Lenti ORF particles, P2RY4 (mGFP-tagged) - Human pyrimidinergic receptor P2Y, G-protein coupled, 4 (P2RY4), 200 uL, >10^7 TU/mL |
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200 µl /
€1,050.00
|
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| OriGene Technologies, Inc. | ||
| RC213891L1V | Lenti ORF particles, P2RY4 (Myc-DDK tagged) - Human pyrimidinergic receptor P2Y, G-protein coupled, 4 (P2RY4) , 200 uL, >10^7 TU/mL |
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|
200 µl /
€940.00
|
|
| OriGene Technologies, Inc. | ||
Mouse Lenti ORF Particles
| Catalog No. | ||
|---|---|---|
| MR222293L2V | Lenti ORF particles, P2ry4 (GFP-tagged) - Mouse pyrimidinergic receptor P2Y, G-protein coupled, 4 (P2ry4), 200 uL, >10^7 TU/mL |
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|
200 µl /
€880.00
|
|
| OriGene Technologies, Inc. | ||
| MR222293L1V | Lenti ORF particles, P2ry4 (Myc-DDK-tagged) - Mouse pyrimidinergic receptor P2Y, G-protein coupled, 4 (P2ry4), 200 uL, >10^7 TU/mL |
|
|
200 µl /
€780.00
|
|
| OriGene Technologies, Inc. | ||
Rat Lenti ORF Particles
| Catalog No. | ||
|---|---|---|
| RR208304L2V | Lenti ORF particles, P2ry4 (GFP-tagged ORF) - Rat pyrimidinergic receptor P2Y, G-protein coupled, 4 (P2ry4), 200 uL, >10^7 TU/mL |
|
|
200 µl /
€880.00
|
|
| OriGene Technologies, Inc. | ||
