PA1 antibody

Principal name

PA1 antibody

Alternative names for PA1 antibody

C16orf53, PAXIP1-associated protein 1, PTIP-associated protein 1

SwissProt ID

P0A921 (Ecoli), Q1LZ80 (Bovin), Q5M865 (Rat), Q99L02 (Mouse), Q9BTK6 (Human)

Gene ID

79447 (C16orf53)

Available reactivities

Hu (Human), Ms (Mouse), Bov (Bovine), Eq (Equine), Gt (Goat), Por (Porcine), Rb (Rabbit)

Available hosts

Rabbit, Mouse

Available applications

Immunoprecipitation (IP), Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E)

Background of PA1 antibody

Steroid receptor co-activators (SRCs) were initially described as nuclear receptor transcription co-activators, but they have recently been determined to co-regulate transcription initiated by other transcription factors. GAS is a recently identified glutamate-rich protein that interacts with SRC1, but not GRIP1 or AIB1, the other two members of the SRC family. GAS can also interact with the alpha subunit of the estrogen receptor (ERalpha), but not other receptors such as the retinoic acid receptor a, suggesting the interaction between GAS and ERalpha is relatively specific. Depletion of GAS by RNA interference in MCF7 cells led to a decrease in the mRNA and protein levels of ER target genes such as pS2, c-Myc and cyclin D1, indicating the role of GAS in the regulation of ER target genes. GAS has also been found to associate with an SET1-like methyltransferase complex specific for H3K4 methylation, suggesting that GAS has multiple roles in transcriptional regulation.

General readings

Liang J., et al. (2009) EMBO Rep. 10(1):51-7.
Cho YW., et al. (2007) J Biol Chem. 282(28):20395-406.

11 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PA1 antibody

Host: Rabbit; Target Name: C16orf53; Sample Tissue: Hela Whole cell lysates; Antibody Dilution: 1.0ug/mlPAGR1 is supported by BioGPS gene expression data to be expressed in HeLa Rabbit IgG Purified Bov, Eq, Gt, Hu, Por, Rb WB
50 µg / €325.00
  OriGene Technologies, Inc.

PA1 (C-term) antibody

Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit Purified Hu, Ms E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

PA1 antibody

PA1 Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

PA1 antibody

Western Blot and Immunoprecipitation: PA1 Antibody [NBP1-06541] - Whole cell lysate from HeLa and 293T cells. PA1 was also immunoprecipitated by another rabbit anti-PA1 antibody and NBP1-06542. Rabbit IgG Aff - Purified Hu IP, WB
0.1 ml / €440.00
  Novus Biologicals Inc.

PA1 antibody

Immunohistochemistry-Paraffin: PA1 Antibody [NBP1-06542] - See Notes, IHC Caption Rabbit IgG Aff - Purified Hu IP, P, WB
0.1 ml / €440.00
  Novus Biologicals Inc.

PA1 antibody

Western Blot: PA1 Antibody [NBP1-76239] - Analysis of GAS in EL4 cell lysate in (A) the absence and (B) the presence of blocking peptide with GAS antibody at 1ug/mL._x000d_ Rabbit Aff - Purified Hu, Ms E, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PA1

PA1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

PA1 (1-254, His-tag)

PA1 Human Purified > 85 % E. coli
0.5 mg / €750.00
  Acris Antibodies GmbH

PA1 (1-254, His-tag)

PA1 Human Purified > 85 % E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

PA1

PA1 Human
0.1 mg / €380.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

PAGR1 overexpression lysate

PAGR1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

11 Item(s)

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