PABPC4 antibody

Principal name

PABPC4 antibody

Alternative names for PABPC4 antibody

PABP4, PABP-4, Polyadenylate-binding protein 4, APP1, APP-1, iPABP, Poly(A)-binding protein 4, Poly(A)-binding protein 4, Inducible poly(A)-binding protein

SwissProt ID

Q13310 (Human)

Gene ID

8761 (PABPC4), 448761 (haao)

Available reactivities

Bov (Bovine), Can (Canine), Chk (Chicken), Hu (Human), Ms (Mouse), Rt (Rat), Ze (Zebrafish), African clawed frog, Eq (Equine), GP (Guinea Pig), Rb (Rabbit), Por (Porcine)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Immunoprecipitation (IP), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Enzyme Immunoassay (E), Frozen Sections (C)

Background of PABPC4 antibody

Poly(A)-binding proteins (PABPs) bind to the poly(A) tail present at the 3-prime ends of most eukaryotic mRNAs. PABPC4 or IPABP (inducible PABP) was isolated as an activation-induced T-cell mRNA encoding a protein. Activation of T cells increased PABPC4 mRNA levels in T cells approximately 5-fold. PABPC4 contains 4 RNA-binding domains and proline-rich C terminus. PABPC4 is localized primarily to the cytoplasm. It is suggested that PABPC4 might be necessary for regulation of stability of labile mRNA species in activated T cells. PABPC4 was also identified as an antigen, APP1 (activated-platelet protein-1), expressed on thrombin-activated rabbit platelets. PABPC4 may also be involved in the regulation of protein translation in platelets and megakaryocytes or may participate in the binding or stabilization of polyadenylates in platelet dense granules.Poly(A)-binding proteins (PABPs) bind to the poly(A) tail present at the 3-prime ends of most eukaryotic mRNAs. PABPC4 or IPABP (inducible PABP) was isolated as an activation-induced T-cell mRNA encoding a protein. Activation of T cells increased PABPC4 mRNA levels in T cells approximately 5-fold. PABPC4 contains 4 RNA-binding domains and proline-rich C terminus. PABPC4 is localized primarily to the cytoplasm. It is suggested that PABPC4 might be necessary for regulation of stability of labile mRNA species in activated T cells. PABPC4 was also identified as an antigen, APP1 (activated-platelet protein-1), expressed on thrombin-activated rabbit platelets. PABPC4 may also be involved in the regulation of protein translation in platelets and megakaryocytes or may participate in the binding or stabilization of polyadenylates in platelet dense granules.Poly(A)-binding proteins (PABPs) bind to the poly(A) tail present at the 3-prime ends of most eukaryotic mRNAs. PABPC4 or IPABP (inducible PABP) was isolated as an activation-induced T-cell mRNA encoding a protein. Activation of T cells increased PABPC4 mRNA levels in T cells approximately 5-fold. PABPC4 contains 4 RNA-binding domains and proline-rich C terminus. PABPC4 is localized primarily to the cytoplasm. It is suggested that PABPC4 might be necessary for regulation of stability of labile mRNA species in activated T cells. PABPC4 was also identified as an antigen, APP1 (activated-platelet protein-1), expressed on thrombin-activated rabbit platelets. PABPC4 may also be involved in the regulation of protein translation in platelets and megakaryocytes or may participate in the binding or stabilization of polyadenylates in platelet dense granules. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

Lehner,B. (2004) Genome Res. 14 (7), 1315-1323

13 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PABPC4 antibody

WB Suggested Anti-PABPC4 Antibody Titration: 0.2-1 ug/ml; Positive Control: HepG2 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

PABPC4 antibody

WB Suggested Anti-PABPC4 Antibody Titration: 1.25 ug/ml; ELISA Titer: 1: 312500; Positive Control: HepG2 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PABPC4 antibody

PABPC4 Rabbit Serum Hu C, E, WB
0.2 ml / €400.00
  Acris Antibodies GmbH

PABPC4 antibody

Immunofluorescence of purified MaxPab antibody to PABPC4 on HeLa cell. [antibody concentration 10 ug/ml] Mouse Serum Hu E(detection), ICC/IF, WB
50 µl / €370.00
  Abnova Taiwan Corp.

PABPC4 antibody

Western Blot analysis of PABPC4 expression in transfected 293T cell line (H00008761-T01) by PABPC4 MaxPab polyclonal antibody.

Lane 1: PABPC4 transfected lysate(72.40 KDa).
Lane 2: Non-transfected lysate. Rabbit Serum Hu E(detection), WB
0.1 ml / €380.00
  Abnova Taiwan Corp.

PABPC4 antibody

Western Blot analysis of PABPC4 expression in transfected 293T cell line (H00008761-T02) by PABPC4 MaxPab polyclonal antibody.

Lane 1: PABPC4 transfected lysate(72.40 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

PABPC4 antibody

Human HepG2; WB Suggested Anti-PABPC4 Antibody Titration: 0.2-1 ug/ml. Positive Control: HepG2 cell lysate; PABPC4 antibody - middle region (ARP40495_P050) in Human HepG2 cells using Western Blot Rabbit Aff - Purified Bov, Can, Chk, Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

PABPC4 antibody

Human Kidney; Rabbit Anti-PABPC4 Antibody. Catalog Number: ARP40496. Paraffin Embedded Tissue: Human Kidney. Cellular Data: Epithelial cells of renal tubule. Antibody Concentration: 4.0-8.0 ug/ml. Magnification: 400X; PABPC4 antibody - N-terminal region (ARP40496_T100) in Human Kidney cells using Immunohistochemistry Rabbit Aff - Purified African clawed frog, Bov, Can, Chk, Hu, Ms, Rt, Ze P, WB
0.1 mg / €310.00
  AVIVA Systems Biology

PABPC4 antibody

Immunohistochemistry-Paraffin: PABPC4 Antibody [NB100-74593] - See Notes, IHC Caption A Rabbit IgG Aff - Purified Hu, Ms IP, P, WB
0.1 ml / €440.00
  Novus Biologicals Inc.

PABPC4 antibody

Western Blot and  Immunoprecipitation: PABP4 Antibody [NB100-74594] - Detection of Human and Mouse PABP4 on HeLa whole cell lysate using NB100-74594. PABP4 was also immunoprecipitated by rabbit anti-PABP4 antibody NB100-74593. Rabbit IgG Aff - Purified Hu, Ms IP, WB
0.1 ml / €440.00
  Novus Biologicals Inc.

PABPC4 antibody

PABPC4 Rabbit Purified Can, Hu P, WB
0.1 mg / €360.00
  Novus Biologicals Inc.

Lysates

Catalog No.    

PABPC4 293T Cell Transient Overexpression Lysate(Denatured)

PABPC4 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

PABPC4 overexpression lysate

PABPC4 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

13 Item(s)

per page
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