PABPN1 antibody

Principal name

PABPN1 antibody

Alternative names for PABPN1 antibody

PAB2, PABP2, PABP-2, Polyadenylate-binding protein 2, Poly(A)-binding protein 2, Nuclear poly(A)-binding protein 1, Polyadenylate-binding nuclear protein 1

SwissProt ID

P42731 (Arath), Q28165 (Bovin), Q7KNF2 (Drome), Q86U42 (Human), Q8CCS6 (Mouse)

Gene ID

8106 (PABPN1)

Available reactivities

Hu (Human), Ms (Mouse), Bov (Bovine), Can (Canine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit), Rt (Rat)

Available hosts

Rabbit

Available applications

Paraffin Sections (P), Western blot / Immunoblot (WB), Flow Cytometry (F), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP)

Background of PABPN1 antibody

PABPN1 is an abundant nuclear protein that binds with high affinity to nascent poly(A) tails. The protein is required for progressive and efficient polymerization of poly(A) tails at the 3' ends of eukaryotic transcripts and controls the size of the poly(A) tail to about 250 nt. At steady-state, this protein is localized in the nucleus whereas a different poly(A) binding protein is localized in the cytoplasm. This gene contains a GCG trinucleotide repeat at the 5' end of the coding region, and expansion of this repeat from the normal 6 copies to 8-13 copies leads to autosomal dominant oculopharyngeal muscular dystrophy (OPMD) disease. Related pseudogenes have been identified on chromosomes 19 and X. Read-through transcription also exists between this gene and the neighboring upstream BCL2-like 2 (BCL2L2) gene.

General readings

Hosgood, H.D. III, et al. Occup Environ Med 66(12):848-853(2009)
Hurt, J.A., et al. J. Cell Biol. 185(2):265-277(2009)
Kuo, H.C., et al. J. Neurol. Sci. 278 (1-2), 21-24 (2009)
Tavanez, J.P., et al. PLoS ONE 4 (7), E6418 (2009)
Maksimova, N.R., et al. Zh Nevrol Psikhiatr Im S S Korsakova 108(6):52-60(2008)

8 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PABPN1 antibody

PABPN1 antibody - N-terminal region validated by WB using C2C12 myoblast cell line at 1.25 ug/ml. Rabbit IgG Purified Bov, Can, GP, Hu, Ms, Por, Rb, Rt ICC/IF, WB
50 µg / €325.00
  OriGene Technologies, Inc.

PABPN1 (C-term) antibody

Western blot analysis of PABPN1 Antibody (C-term) Cat.-No AP53148PU-N in Hela cell line lysates (35ug/lane). This demonstrates the PABPN1 antibody detected the PABPN1 protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

PABPN1 antibody

Mouse C2C12; PABPN1 antibody - N-terminal region (ARP40539_P050) validated by WB using C2C12 myoblast cell line at 1.25 ug/ml.; PABPN1 antibody - N-terminal region (ARP40539_P050) in Mouse C2C12 cells using Western Blot Rabbit Aff - Purified Bov, Can, Hu, Ms WB
50 µg / €350.00
  AVIVA Systems Biology

PABPN1 antibody

PABPN1 Rabbit IgG Hu P, WB
0.1 ml / €420.00
  Novus Biologicals Inc.

PABPN1 antibody

Immunofluorescence: PABPN1 Antibody (EP3000Y) [NBP1-40518] - Immunofliorescent staining of HeLa cells using anti-PABP2 Rabbit IgG EP3000Y Hu, Ms F, ICC/IF, IP, P, WB
0.1 ml / €490.00
  Novus Biologicals Inc.

PABPN1 antibody

Western Blot: PABPN1 Antibody [NBP1-57216] - This Anti-PABPN1 antibody was used in Western Blot of NCI-H226     tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu ICC/IF, WB
50 µg / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PABPN1 (119-306, His-tag)

PABPN1 Human Purified > 95 % by SDS - PAGE E. coli
0.5 mg / €730.00
  Acris Antibodies GmbH

PABPN1 (119-306, His-tag)

PABPN1 Human Purified > 95 % by SDS - PAGE E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

8 Item(s)

per page
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