PACAP type III receptor / VIP Receptor 2 antibody

Principal name

PACAP type III receptor / VIP Receptor 2 antibody

Alternative names for PACAP type III receptor / VIP Receptor 2 antibody

VIPR2, VIP2R, Vasoactive intestinal polypeptide receptor 2, PACAP-R-3, PACAPR3, VIPR-2, VIP-R2, Pituitary adenylate cyclase-activating polypeptide type III receptor

SwissProt ID

P35000 (Rat), P41587 (Human), P41588 (Mouse)

Gene ID

7434 (VIPR2), 22355 (Vipr2), 29555

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Mky (Monkey), Bov (Bovine), Por (Porcine), Gorilla

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Frozen Sections (C), Flow Cytometry (F), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of PACAP type III receptor / VIP Receptor 2 antibody

The vasoactive intestinal peptide (VIP) and the pituitary adenylate cylaseactivating polypeptide (PACAP) belong to a superfamily of peptide hormones that include glucagon, secretin and growth hormone releasing hormone. The effects of VIP and PACAP are mediated by three G-protein coupled receptors, VPAC1, VPAC2 and the PACAP receptor (also designated PAC1-R). The VPAC receptors have equal affinities for VIP and PACAP, which stimulate the activation of adenylyl cyclase. Both VPAC1, a 47 kDa protein, and VPAC2, a 65 kDa protein, are abundantly expressed in brain and T cells, where they modulate neuronal differentiation and T cell activation, respectively. The PACAP receptor is a seven transmembrane protein that produces at least eight isoforms by alternative splicing. Each isoform is associated with a specific signaling pathway and a specific expression pattern. The PACAP receptor, which is thought to play an integral role in brain development, preferentially binds PACAP in order to stimulate a cAMP-protein kinase A signaling pathway.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PACAP type III receptor / VIP Receptor 2 (C-term) antibody

  VPAC2 / VIPR2 Rabbit Polyclonal (C-Terminus) Antibody  
PACAP type III receptor /  VIP Receptor 2 Rabbit Aff - Purified Hu, Mky P
50 µg / €425.00
  OriGene Technologies, Inc.

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