PACRG antibody

Principal name

PACRG antibody

Alternative names for PACRG antibody

Parkin coregulated gene protein, GLUP, PARK2 coregulated gene protein, PARK2CRG, Molecular chaperone/chaperonin-binding protein

SwissProt ID

Q96M98 (Human), Q9DAK2 (Mouse)

Gene ID

135138 (PACRG), 69310 (Pacrg)

Available reactivities

Chk (Chicken), Hu (Human), Rt (Rat), Ze (Zebrafish), Ms (Mouse), Bov (Bovine), Eq (Equine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), Frozen Sections (C), ELISA (detection) (E(detection))

Background of PACRG antibody

PACRG is a protein that is conserved across metazoans. In vertebrates, this gene is linked in a head-to-head arrangement with the adjacent parkin gene, which is associated with autosomal recessive juvenile Parkinson's disease. These genes are co-regulated in various tissues and they share a bi-directiol promoter. Both genes are associated with susceptibility to leprosy. The parkin co-regulated gene protein forms a large molecular complex with chaperones, including heat shock proteins 70 and 90, and chaperonin components. This protein is also a component of Lewy bodies in Parkinson's disease patients, and it suppresses unfolded Pael receptor-induced neurol cell death.This gene encodes a protein that is conserved across metazoans. In vertebrates, this gene is linked in a head-to-head arrangement with the adjacent parkin gene, which is associated with autosomal recessive juvenile Parkinson's disease. These genes are co-regulated in various tissues and they share a bi-directiol promoter. Both genes are associated with susceptibility to leprosy. The parkin co-regulated gene protein forms a large molecular complex with chaperones, including heat shock proteins 70 and 90, and chaperonin components. This protein is also a component of Lewy bodies in Parkinson's disease patients, and it suppresses unfolded Pael receptor-induced neurol cell death. Multiple transcript variants encoding different isoforms have been found for this gene.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PACRG (204-215) antibody

Colon: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit Aff - Purified Chk, Hu, Ms E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

PACRG (204-215) antibody

  Rabbit polyclonal anti-PACRG antibody  
WB using Anti-PACRG antibody shows detection of a band ~40 kDa corresponding to human PACRG (arrowhead lane 1). Specific reactivity with this band is blocked when the antibody is pre-incubated with the immunizing peptide (lane 2). The primary antibody diluted to 1:1,500 for 2h at RTfollowed by washes and reaction with a 1:10,000 dilution of IRDye800 conjugated Gt-a-Rabbit IgG [H&L] MX  for 45 min at room temperature. Rabbit IgG Aff - Purified Chk, Hu, Ms E, WB
0.1 mg / €356.00
  OriGene Technologies, Inc.

PACRG antibody

  Rabbit Polyclonal Anti-PACRG Antibody  
WB Suggested Anti-PACRG Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: 293T cell lysate Rabbit IgG Purified Bov, Eq, GP, Hu, Ms, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

PACRG (204-215) antibody

PACRG Staining of human colon: Formalin-Fixed Paraffin-Embedded (FFPE). Rabbit IgG Aff - Purified Hu, Rt, Ze C, E, ICC/IF, P, WB
50 µg / €460.00
  Neuromics Antibodies

CRISPR

Catalog No. Species Donor Vector  

PACRG - human gene knockout kit via CRISPR

PACRG - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

PACRG - human gene knockout kit via CRISPR

PACRG - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

PACRG - human gene knockout kit via CRISPR

PACRG - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

PACRG - human gene knockout kit via CRISPR

PACRG - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PACRG (transcript variant 2)

  Recombinant protein of human PARK2 co-regulated (PACRG), transcript variant 2  
PACRG Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

PACRG overexpression lysate

PACRG overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

PACRG overexpression lysate

PACRG overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, PACRG (mGFP-tagged)-Human PARK2 co-regulated (PACRG), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, PACRG (mGFP-tagged)-Human PARK2 co-regulated (PACRG), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €960.00
  OriGene Technologies, Inc.

Lenti ORF particles, PACRG (Myc-DDK-tagged)-Human PARK2 co-regulated (PACRG), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, PACRG (Myc-DDK-tagged)-Human PARK2 co-regulated (PACRG), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €860.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Pacrg (GFP-tagged) - Mouse PARK2 co-regulated (Pacrg), 200 uL, >10^7 TU/mL

Lenti ORF particles, Pacrg (GFP-tagged) - Mouse PARK2 co-regulated (Pacrg), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Pacrg (Myc-DDK-tagged) - Mouse PARK2 co-regulated (Pacrg), 200 uL, >10^7 TU/mL

Lenti ORF particles, Pacrg (Myc-DDK-tagged) - Mouse PARK2 co-regulated (Pacrg), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

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