PACSIN1 antibody

Principal name

PACSIN1 antibody

Alternative names for PACSIN1 antibody

KIAA1379, Protein kinase C and casein kinase substrate in neurons protein 1

SwissProt ID

A7MBI0 (Bovin), Q61644 (Mouse), Q9BY11 (Human), Q9Z0W5 (Rat)

Gene ID

29993 (PACSIN1), 23969 (Pacsin1), 29704

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Por (Porcine)

Available hosts

Rabbit, Goat, Mouse, Rat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection))

Background of PACSIN1 antibody

Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The STE group (homologs of yeast Sterile 7, 11, 20 kinases) consists of 50 kinases related to the mitogen-activated protein kinase (MAPK) cascade families (Ste7/MAP2K, Ste11/MAP3K, and Ste20/MAP4K). MAP kinase cascades, consisting of a MAPK and one or more upstream regulatory kinases (MAPKKs) have been best characterized in the yeast pheromone response pathway. Pheromones bind to Ste cell surface receptors and activate yeast MAPK pathway.

General readings

Modregger J, DiProspero NA, Charles V, Tagle DA, Plomann M.
PACSIN 1 interacts with huntingtin and is absent from synaptic varicosities in
presymptomatic Huntington's disease brains.
Hum Mol Genet. 2002 Oct 1;11(21):2547-58.
PMID: 12354780

20 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PACSIN1 (N-term) antibody

  Goat Polyclonal Antibody against PACSIN1  
TA302751 (1µg/ml) staining of Human Brain (hippocampus) lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Hu, Por WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PACSIN1 antibody

  Rabbit Polyclonal Anti-PACSIN1 Antibody  
WB Suggested Anti-PACSIN1 Antibody Titration: 2.5 ug/ml; ELISA Titer: 1:62500; Positive Control: Transfected 293T Rabbit IgG Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PACSIN1 antibody

  Rat Monoclonal anti-PACSIN1 Antibody  
Tissue extracts of mouse brain (lane 1) or mouse liver (lane 2) were resolved by electrophoresis, transferred to nitrocellulose, and probed with purified monoclonal anti-PACSIN1 (clone 10A6B55) antibody. Proteins were visualized using an anti-rat IgG secondary conjugated to HRP and chemiluminescence detection. Rat 10A6B55 Purified Ms WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PACSIN1 (N-term) antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Rabbit Ig Purified Hu, Ms P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

PACSIN1 (Center) antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Rabbit Ig Purified Hu, Ms P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

PACSIN1 - human gene knockout kit via CRISPR

PACSIN1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

PACSIN1 - human gene knockout kit via CRISPR

PACSIN1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

PACSIN1 - human gene knockout kit via CRISPR

PACSIN1 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

PACSIN1 - human gene knockout kit via CRISPR

PACSIN1 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Pacsin1 - mouse gene knockout kit via CRISPR

Pacsin1 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Pacsin1 - mouse gene knockout kit via CRISPR

Pacsin1 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Pacsin1 - mouse gene knockout kit via CRISPR

Pacsin1 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Pacsin1 - mouse gene knockout kit via CRISPR

Pacsin1 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PACSIN1

  Recombinant protein of human protein kinase C and casein kinase substrate in neurons 1 (PACSIN1)  
PACSIN1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, PACSIN1 (mGFP-tagged) - Human protein kinase C and casein kinase substrate in neurons 1 (PACSIN1), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, PACSIN1 (mGFP-tagged) - Human protein kinase C and casein kinase substrate in neurons 1 (PACSIN1), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, PACSIN1 (Myc-DDK tagged) - Human protein kinase C and casein kinase substrate in neurons 1 (PACSIN1), transcript variant 1 , 200 uL, >10^7 TU/mL

Lenti ORF particles, PACSIN1 (Myc-DDK tagged) - Human protein kinase C and casein kinase substrate in neurons 1 (PACSIN1), transcript variant 1 , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Pacsin1 (GFP-tagged) - Mouse protein kinase C and casein kinase substrate in neurons 1 (Pacsin1), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, Pacsin1 (GFP-tagged) - Mouse protein kinase C and casein kinase substrate in neurons 1 (Pacsin1), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,040.00
  OriGene Technologies, Inc.

Lenti ORF particles, Pacsin1 (Myc-DDK-tagged) - Mouse protein kinase C and casein kinase substrate in neurons 1 (Pacsin1), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, Pacsin1 (Myc-DDK-tagged) - Mouse protein kinase C and casein kinase substrate in neurons 1 (Pacsin1), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €930.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Pacsin1 (GFP-tagged ORF) - Rat protein kinase C and casein kinase substrate in neurons 1 (Pacsin1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Pacsin1 (GFP-tagged ORF) - Rat protein kinase C and casein kinase substrate in neurons 1 (Pacsin1), 200 uL, >10^7 TU/mL  
200 µl / €1,040.00
  OriGene Technologies, Inc.

Lenti ORF particles, Pacsin1 (Myc-DDK-tagged ORF) - Rat protein kinase C and casein kinase substrate in neurons 1 (Pacsin1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Pacsin1 (Myc-DDK-tagged ORF) - Rat protein kinase C and casein kinase substrate in neurons 1 (Pacsin1), 200 uL, >10^7 TU/mL  
200 µl / €930.00
  OriGene Technologies, Inc.

20 Item(s)

per page
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