PACSIN1 antibody

Principal name

PACSIN1 antibody

Alternative names for PACSIN1 antibody

KIAA1379, Protein kinase C and casein kinase substrate in neurons protein 1

SwissProt ID

A7MBI0 (Bovin), Q61644 (Mouse), Q9BY11 (Human), Q9Z0W5 (Rat)

Gene ID

29993 (PACSIN1), 23969 (Pacsin1), 29704

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Por (Porcine)

Available hosts

Rabbit, Goat, Mouse, Rat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection))

Background of PACSIN1 antibody

Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The STE group (homologs of yeast Sterile 7, 11, 20 kinases) consists of 50 kinases related to the mitogen-activated protein kinase (MAPK) cascade families (Ste7/MAP2K, Ste11/MAP3K, and Ste20/MAP4K). MAP kinase cascades, consisting of a MAPK and one or more upstream regulatory kinases (MAPKKs) have been best characterized in the yeast pheromone response pathway. Pheromones bind to Ste cell surface receptors and activate yeast MAPK pathway.

General readings

Modregger J, DiProspero NA, Charles V, Tagle DA, Plomann M.
PACSIN 1 interacts with huntingtin and is absent from synaptic varicosities in
presymptomatic Huntington's disease brains.
Hum Mol Genet. 2002 Oct 1;11(21):2547-58.
PMID: 12354780

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PACSIN1 (N-term) antibody

TA302751 (1µg/ml) staining of Human Brain (hippocampus) lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Hu, Por WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PACSIN1 antibody

WB Suggested Anti-PACSIN1 Antibody Titration: 2.5 ug/ml; ELISA Titer: 1:62500; Positive Control: Transfected 293T Rabbit IgG Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PACSIN1 antibody

Tissue extracts of mouse brain (lane 1) or mouse liver (lane 2) were resolved by electrophoresis, transferred to nitrocellulose, and probed with purified monoclonal anti-PACSIN1 (clone 10A6B55) antibody. Proteins were visualized using an anti-rat IgG secondary conjugated to HRP and chemiluminescence detection. Rat 10A6B55 Purified Ms WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PACSIN1 (N-term) antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Rabbit Ig Purified Hu, Ms P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

PACSIN1 (Center) antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Rabbit Ig Purified Hu, Ms P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

PACSIN1 antibody

PACSIN1 MaxPab polyclonal antibody. Western Blot analysis of PACSIN1 expression in rat brain. Mouse Purified Hu, Rt E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

PACSIN1 antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with PACSIN1 polyclonal antibody ( Cat # PAB3299 ) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma. Rabbit Hu, Ms E, P, WB
0.4 ml / €390.00
  Abnova Taiwan Corp.

PACSIN1 antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with PACSIN1 polyclonal antibody ( Cat # PAB3300 ) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. HC = hepatocarcinoma. Rabbit Hu, Ms E, P, WB
0.4 ml / €390.00
  Abnova Taiwan Corp.

PACSIN1 antibody

PACSIN1 polyclonal antibody ( Cat # PAB6089 ) staining ( 1 µg/ml ) of human brain ( hippocampus ) lysate ( 35 µg protein in RIPA buffer ) . Primary incubation was 1 hour. Detected by chemiluminescenc. Goat Hu E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

PACSIN1 antibody

Human 293T; WB Suggested Anti-PACSIN1 Antibody Titration: 2.5ug/ml. ELISA Titer: 1:62500. Positive Control: Transfected 293T; PACSIN1 antibody - C-terminal region (AVARP13052_T100) in Human 293T cells using Western Blot Rabbit Aff - Purified Bov, Can, Hu, Ms, Rt P, WB
0.1 mg / €310.00
  AVIVA Systems Biology

CRISPR

Catalog No. Species Donor Vector  

PACSIN1 - human gene knockout kit via CRISPR

  PACSIN1 - human gene knockout kit via CRISPR  
PACSIN1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

PACSIN1 - human gene knockout kit via CRISPR

  PACSIN1 - human gene knockout kit via CRISPR  
PACSIN1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

PACSIN1 - human gene knockout kit via CRISPR

  PACSIN1 - human gene knockout kit via CRISPR  
PACSIN1 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

PACSIN1 - human gene knockout kit via CRISPR

  PACSIN1 - human gene knockout kit via CRISPR  
PACSIN1 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PACSIN1

PACSIN1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

PACSIN1

PACSIN1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

PACSIN1

PACSIN1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

PACSIN1 293T Cell Transient Overexpression Lysate(Denatured)

PACSIN1 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, PACSIN1 (mGFP-tagged) - Human protein kinase C and casein kinase substrate in neurons 1 (PACSIN1), transcript variant 1, 200 uL, >10^7 TU/mL

  Lenti ORF particles, PACSIN1 (mGFP-tagged) - Human protein kinase C and casein kinase substrate in neurons 1 (PACSIN1), transcript variant 1, 200 uL, >10^7 TU/mL  
Lenti ORF particles, PACSIN1 (mGFP-tagged) - Human protein kinase C and casein kinase substrate in neurons 1 (PACSIN1), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, PACSIN1 (Myc-DDK tagged) - Human protein kinase C and casein kinase substrate in neurons 1 (PACSIN1), transcript variant 1 , 200 uL, >10^7 TU/mL

  Lenti ORF particles, PACSIN1 (Myc-DDK tagged) - Human protein kinase C and casein kinase substrate in neurons 1 (PACSIN1), transcript variant 1 , 200 uL, >10^7 TU/mL  
Lenti ORF particles, PACSIN1 (Myc-DDK tagged) - Human protein kinase C and casein kinase substrate in neurons 1 (PACSIN1), transcript variant 1 , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

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