PADI4 antibody
Principal name
PADI4 antibody
Alternative names for PADI4 antibody
PDI4, PAD4, PDI5, PADI5, PADI-H, HL-60 PAD, Protein-arginine deiminase type-4, Peptidylarginine deiminase IV, Protein-arginine deiminase type IV
Ncbi ID
NP_036519.2, 9606, NM_012387, NP_036519, NP_035191.2, NM_011061, NM_017227
Available reactivities
Available hosts
Available applications
Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Frozen Sections (C), Immunoprecipitation (IP), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Flow Cytometry (F), Luminex (LMNX), ChIP assay (ChIP)
Background of PADI4 antibody
PADI4 (Peptidylarginine Deiminase, Type IV), also known as PAD or PAD4, is a human protein which in humans is encoded by the PADI4 gene. Peptidylarginine deiminases, such as PADI4, make up a family of posttranslational modification enzymes that convert arginine residues to citrulline residues in the presence of calcium ion (Nakashima et al., 1999). Suzuki et al. (2003) found from sequence data that the PADI4 gene maps to 1p36. Cuthbert et al. (2004) described a process, deimination, that converts histone arginine to citrulline and antagonizes arginine methylation. They showed that PADI4 specifically deiminated arg2, arg8, arg17, and arg26 in the H3 tail. Deimination by PADI4 prevented arginine methylation by CARM1. Dimethylation of arginines prevented deimination by PADI4, although monomethylation still allowed deimination to take place. In vivo targeting experiments on an endogenous promoter demonstrated that PADI4 could repress hormone receptor-mediated gene induction. PADI4 was recruited to the pS2 promoter following hormone induction when the gene was transcriptionally downregulated, consistent with a repressive role for PADI4.
General readings
Wang Y, Wysocka J, Sayegh J, Lee YH, Perlin JR, Leonelli L, Sonbuchner LS, McDonald CH, Cook RG, Dou Y, Roeder RG, Clarke S, Stallcup MR, Allis CD, Coonrod SA. Human PAD4 regulates histone arginine methylation levels via demethylimination. Science. 2004 Oct 8;306(5694):279-83.
































































- Quick-Filters:
- Highly Validated (5)
Primary Antibodies
Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
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TA504813 | PADI4 antibody |
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PADI4 mouse monoclonal antibody, clone OTI4H5 (formerly 4H5) | |||||||
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Mouse | IgG2a | OTI4H5 | Purified | Hu | F, ICC/IF, P, WB |
0.1 ml /
€379.00
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OriGene Technologies, Inc. | |||||||
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Top Selling product! Highly validated antibody! |
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TA332458 | PADI4 antibody |
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Rabbit anti-PADI4 Polyclonal Antibody | |||||||
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Rabbit | IgG | Purified | Hu, Rt |
0.1 mg /
€335.00
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OriGene Technologies, Inc. | |||||||
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Highly validated antibody! |
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TA504814 | PADI4 antibody |
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PADI4 mouse monoclonal antibody, clone OTI5E7 (formerly 5E7) | |||||||
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Mouse | IgG1 | OTI5E7 | Purified | Hu | P, WB |
0.1 ml /
€360.00
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OriGene Technologies, Inc. | |||||||
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Highly validated antibody! |
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TA504887 | PADI4 antibody |
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PADI4 mouse monoclonal antibody, clone OTI6A2 (formerly 6A2) | |||||||
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Mouse | IgG1 | OTI6A2 | Purified | Hu | F, ICC/IF, P, WB |
0.1 ml /
€360.00
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OriGene Technologies, Inc. | |||||||
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Highly validated antibody! |
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TA504896 | PADI4 antibody |
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PADI4 mouse monoclonal antibody, clone OTI5C10 (formerly 5C10) | |||||||
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Mouse | IgG1 | OTI5C10 | Purified | Hu | P, WB |
0.1 ml /
€360.00
|
OriGene Technologies, Inc. | |||||||
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Highly validated antibody! |
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TA302558 | PADI4 (N-term) antibody |
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Goat Polyclonal Antibody against PAD4 / PADI4 | |||||||
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Goat | Aff - Purified | Chimp, Hu | WB |
0.1 mg /
€360.00
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OriGene Technologies, Inc. | |||||||
TA308535 | PADI4 antibody |
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Rabbit Polyclonal antibody to PAD4 (peptidyl arginine deiminase, type IV) | |||||||
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Rabbit | IgG | Aff - Purified | Hu | ChIP, ICC/IF, P, WB |
0.1 ml /
€415.00
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OriGene Technologies, Inc. | |||||||
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TA321821 | PADI4 antibody |
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Anti-PADI4 Rabbit Polyclonal Antibody | |||||||
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Rabbit | IgG | Purified | Hu, Ms, Rt | E, P |
0.1 ml /
€335.00
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|
OriGene Technologies, Inc. | |||||||
TA336865 | PADI4 antibody |
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Rabbit Polyclonal PADI4 Antibody | |||||||
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Rabbit | Purified | Ms | C, P |
0.1 ml /
€395.00
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OriGene Technologies, Inc. | |||||||
TA347254 | PADI4 antibody |
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Rabbit Polyclonal PADI4 Antibody | |||||||
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Rabbit | IgG | Purified | Hu | E |
0.1 ml /
€285.00
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|
OriGene Technologies, Inc. | |||||||
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TA504791 | PADI4 antibody |
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PADI4 mouse monoclonal antibody, clone OTIE1 (formerly E1) | |||||||
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Mouse | IgG1 | OTIE1 | Purified | Hu | ICC/IF, P, WB |
0.1 ml /
€360.00
|
OriGene Technologies, Inc. | |||||||
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TA504897 | PADI4 antibody |
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PADI4 mouse monoclonal antibody, clone OTI5B7 (formerly 5B7) | |||||||
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Mouse | IgG2a | OTI5B7 | Purified | Hu | F, WB |
0.1 ml /
€360.00
|
OriGene Technologies, Inc. | |||||||
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TA600440 | PADI4 antibody |
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Luminex validated PADI4 mouse monoclonal antibody clone (4H5, clone OTI4H5 (formerly 4H5) | |||||||
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Mouse | IgG1 | OTI4H5 | Purified | Hu | LMNX |
0.1 mg /
€350.00
|
OriGene Technologies, Inc. | |||||||
TA600441 | PADI4 antibody |
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Luminex validated PADI4 mouse monoclonal antibody clone (5B7, clone OTI5B7 (formerly 5B7) | |||||||
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Mouse | IgG1 | OTI5B7 | Purified | Hu | LMNX |
0.1 mg /
€360.00
|
OriGene Technologies, Inc. | |||||||
TA600442 | PADI4 antibody |
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Luminex and ELISA validated PADI4 mouse monoclonal antibody clone (5E7, clone OTI5E7 (formerly 5E7) | |||||||
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Mouse | IgG1 | OTI5E7 | Purified | Hu | E, LMNX |
0.1 mg /
€350.00
|
OriGene Technologies, Inc. | |||||||
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TA700440 | PADI4 antibody |
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Luminex validated biotinylated PADI4 mouse monoclonal antibody (clone 5C10), clone OTI5C10 (formerly 5C10) | |||||||
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Mouse | IgG1 | OTI5C10 | Purified | Hu | LMNX |
50 µg /
€360.00
|
OriGene Technologies, Inc. | |||||||
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TA700441 | PADI4 antibody |
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Luminex validated biotinylated PADI4 mouse monoclonal antibody (clone 4H5), clone OTI4H5 (formerly 4H5) | |||||||
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Mouse | IgG1 | OTI4H5 | Purified | Hu | E, LMNX |
50 µg /
€360.00
|
OriGene Technologies, Inc. | |||||||
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AP12282PU-N | PADI4 (C-term) antibody |
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Rabbit | Ig | Purified | Hu | WB |
0.4 ml /
€415.00
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OriGene Technologies GmbH | |||||||
AP55150SU-N | PADI4 antibody |
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Rabbit | Serum | Hu, Ms, Rt | C, E, IP, WB |
0.2 ml /
€430.00
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OriGene Technologies GmbH |
CRISPR
Catalog No. | Species | Donor Vector | |
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KN312748 | Padi4 - mouse gene knockout kit via CRISPR |
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Mouse | GFP-Puro |
1 kit /
€1,290.00
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OriGene Technologies, Inc. |