PAK2 antibody

Principal name

PAK2 antibody

Alternative names for PAK2 antibody

PAK 2, PAK-2, Gamma-PAK, PAK gamma, PAK65, p21-activated kinase 2, p58, Serine/threonine-protein kinase PAK 2

SwissProt ID

Q13177 (Human), Q29502 (Rabit), Q64303 (Rat), Q8CIN4 (Mouse)

Gene ID

5062 (PAK2), 100910732 (LOC100910732), 224105 (Pak2), 29432

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Rb (Rabbit), Bov (Bovine), Mky (Monkey)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of PAK2 antibody

PAK2 is a ubiquitously expressed, 64kDa, serine/threonine protease found at higher levels in skeletal muscle, ovary, thymus and spleen. p21-activated kinases (PAKs) bind activated Cdc42 and Rac via a Cdc42/Rac interactive binding (CRIB) domain. Group 1 PAK kinases (PAK1, 2 and 3) regulate the activity of an adjacent conserved autoinhibitory domain and are associated with cellular processes, including cytoskeleton rearrangement, apoptosis and MAP kinase signalling. Group 2 PAKs (PAK4, 5, and 6) lack the autoinhibitory domain and are not activated by Cdc42/Rac binding.
PAK2 has a cytostatic effect on cells and is activated in response to cellular stresses such hyperosmolarity, serum starvation, contact inhibition and DNA damage from radiation and chemicals. Unlike other PAKs, PAK2 can be activated by proteolytic cleavage to generate a constitutively active fragment, PAK2p34, which induces a cell death response. This induction is thought to be regulated by Rho GTPase-activating protein 10 which inhibits the protein kinase activity of PAK2p34 and causes it to localise to the perinuclear region instead of the nucleus. PAK2 may also play a role in X-linked mental retardation.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PAK2 (N-term) antibody

  Rabbit Polyclonal PAK2 Antibody  
Western blot analysis of PAK2 in Jurkat lysate with PAK2 antibody at (A) 0.5, (B) 1 and (C) 2 ug/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PAK2 (C-term) antibody

  Rabbit Polyclonal PAK2 Antibody  
Western blot analysis of PAK2 in Jurkat lysate with PAK2 antibody at (A) 0.5 and (B) 1 ug/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PAK2 antibody

  Rabbit polyclonal PAK2 (Ab-192) antibody  
Western blot analysis of extracts from HepG2 cells, treated with serum (20%, 15mins), using PAK2 (Ab-192) antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

PAK2 antibody

  Rabbit polyclonal PAK2 (Ab-141) antibody  
Western blot analysis of extracts from HeLa cells, treated with TSA (400nM, 24hours), using PAK2 (Ab-141) antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

PAK2 antibody

  Rabbit polyclonal PAK2 (Ab-197) antibody  
Western blot analysis of extracts from HT-29 cells, using PAK2 (Ab-197) antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

PAK2 antibody

  Rabbit polyclonal PAK2 (Ser197) antibody(Phospho-specific)  
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using PAK2 (Phospho-Ser197) antibody.The picture on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

PAK2 antibody

  Rabbit Polyclonal Anti-PAK2 Antibody  
Gel: 10%SDS-PAGE, Lysate: 20 ug, Lane: A172 cells, Primary antibody: (PAK2 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 minutes Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

PAK2 antibody

Immunohistochemical analysis of paraffin-embedded human lung cancer (left) and gastric cancer (right) using PAK2 antibody Cat.-No aM063SU-N with DAB staining. Mouse IgG1 3B5 Ascites Hu, Mky ICC/IF, P, WB
0.1 ml / €450.00
  Acris Antibodies GmbH

PAK2 antibody

PAK2 Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €390.00
  Acris Antibodies GmbH

PAK2 (C-term) antibody

Western blot analysis of whole cell lysate from Jurkat human T-cell leukemia cells probed with Rabbit anti Human PAK2 AP05605PU-S at 0.5 (A) and 1(B) µg/ml. Rabbit IgG Purified Hu, Ms, Rt P, WB
0.1 mg / €330.00
  Acris Antibodies GmbH

PAK2 antibody

Skeletal muscle: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit Aff - Purified Hu, Ms, Rt P, WB
50 µg / €470.00
  Acris Antibodies GmbH

PAK2 antibody

Figure 2. Formalin-Fixed Paraffin-Embedded (FFPE) on Skeletal Muscle. Rabbit Aff - Purified Hu, Ms, Rt P, WB
50 µg / €470.00
  Acris Antibodies GmbH

PAK2 (N-term) antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Rabbit Ig Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

PAK2 antibody

Immunohistochemistry (IHC) analyzes of PAKγ antibody (Cat.-No.: AP21121PU-N) in paraffin-embedded human heart tissue. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

PAK2 pSer197 antibody

Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue, using PAK2 (Phospho-Ser197) antibody AP55770PU-N (left)or the same antibody preincubated with blocking peptide (right). Rabbit Aff - Purified Hu, Ms, Rt P
0.1 ml / €340.00
  Acris Antibodies GmbH

PAK2 pSer197 antibody

Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue, using PAK2 (Phospho-Ser197) antibody AP55770PU-N (left)or the same antibody preincubated with blocking peptide (right). Rabbit Aff - Purified Hu, Ms, Rt P
50 µl / €270.00
  Acris Antibodies GmbH

PAK2 pSer20 antibody

Immunohistochemistry analysis of paraffin-embedded human colon carcinoma, using PAK2 (Phospho-Ser20) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
50 µg / €230.00
  Assay Biotech

PAK2 pSer20 antibody

Immunohistochemistry analysis of paraffin-embedded human colon carcinoma, using PAK2 (Phospho-Ser20) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €330.00
  Assay Biotech

PAK2 pSer141 antibody

Western blot analysis of extracts from HepG2 cells treated with Adriamycin 0.5uM 24h/Jurkat cells treated with PMA 125ng/ml 30', using PAK2 (Phospho-Ser141) Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
50 µg / €230.00
  Assay Biotech

PAK2 pSer141 antibody

Western blot analysis of extracts from HepG2 cells treated with Adriamycin 0.5uM 24h/Jurkat cells treated with PMA 125ng/ml 30', using PAK2 (Phospho-Ser141) Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €330.00
  Assay Biotech

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