PAK6 antibody

Principal name

PAK6 antibody

Alternative names for PAK6 antibody

p21-activated kinase 6, PAK-6, Serine/threonine-protein kinase PAK 6, PAK5, PAK-5

SwissProt ID

Q3ULB5 (Mouse), Q5R8Z4 (Ponab), Q9NQU5 (Human)

Gene ID

106821730 (BUB1B-PAK6), 56924 (PAK6), 214230 (Pak6)

Available reactivities

Av (Birds), Bt (Bat), Bov (Bovine), Can (Canine), Eq (Equine), Gt (Goat), Hu (Human), Mky (Monkey), Ms (Mouse), Prim (Primate), Rb (Rabbit), Rt (Rat), Xen (Xenopus), Bear

Available hosts

Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Paraffin Sections (P), Immunoprecipitation (IP), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of PAK6 antibody

Serine/threonine-protein kinase PAK 6(p21 Protein-activated Kinase 6) is an enzyme that in humans is encoded by the PAK6 gene. The PAK6 gene is mapped to chromosome 15q15.1 based on an alignment of the PAK6 sequence with the genomic sequence. This gene encodes a protein that shares a high degree of sequence similarity with p21-activated kinase (PAK) family members. The proteins of this family are Rac/Cdc42-associated Ste20-like Ser/Thr protein kinases, characterized by a highly conserved amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. PAK kinases are implicated in the regulation of a number of cellular processes, including cytoskeleton rearrangement, apoptosis and the MAP kinase signaling pathway. The protein encoded by this gene was found to interact with androgen receptor (AR), which is a steroid hormone-dependent transcription factor that is important for male sexual differentiation and development. The p21-activated protein kinase 6 gene was found to be highly expressed in testis and prostate tissues and the encoded protein was shown to cotranslocate into the nucleus with AR in response to androgen.

General readings

Liu, C.Y., et al. Carcinogenesis 31(7):1259-1263(2010)
Guey, L.T., et al. Eur. Urol. 57(2):283-292(2010)
Lee, E.J., et al. Oncol. Res. 18(9):401-408(2010)
Hosgood, H.D. III, et al. Respir Med 103(12):1866-1870(2009)
Shen, M., et al. Environ. Mol. Mutagen. 50(4):285-290(2009)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PAK6 antibody

  Rabbit Polyclonal PAK6 Antibody  
Western blot analysis of PAK6 in Raji lysate with PAK6 antibody at (A) 1, (B) 2, and (C) 4 ug/mL. Rabbit IgG Aff - Purified Hu E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PAK6 (Center) antibody

  Rabbit polyclonal PAK6 Antibody (Center)  
PAK6 Antibody (Center) (Cat. #TA324474) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the PAK6 antibody detected the PAK6 protein (arrow). Rabbit Ig Aff - Purified Hu ICC/IF, P, WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

PAK6 antibody

  Rabbit Polyclonal Anti-PAK6 Antibody (Linker Domain)  
Anti-PAK6 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Hu P
50 µg / €400.00
  OriGene Technologies, Inc.

PAK6 (Linker Dom.) antibody

  Rabbit Polyclonal Anti-PAK6 Antibody (Linker Domain)  
Anti-PAK6 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Hu P
50 µg / €400.00
  OriGene Technologies, Inc.

PAK6 antibody

  Rabbit Polyclonal Anti-PAK6 Antibody  
The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using (PAK6 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200) Rabbit IgG Purified Hu, Ms E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

PAK6 (N-term) antibody

Testis: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit Aff - Purified Av, Bear, Bov, Bt, Can, Elephant, Eq, Gt, Hu, Mky, Ms, Platypus, Prim, Rb, Rt, Xen E, P
50 µg / €470.00
  Acris Antibodies GmbH

PAK6 antibody

Western blot analysis of anti-PAK6 Pab in lysates from transiently transfected COS7 cells. Lane 1: negative control, Lane 2: PAK1-expressing cells, Lane 3: PAK2-expressing cells, Lane 4: PAK4-expressing cells, Lane 5: PAK5-expressing cells, and Lane 6: PAK6-expressing cells. PAK6 (arrow) was detected using purified Pab. Rabbit Ig Purified Hu IP, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

PAK6 pSer602/560 antibody

Western blot analysis of extracts from HeLa cells (Lane 2), using PAK5/6 (Phospho-Ser602/Ser560) Antibody AP55829PU-N. The lane on the left is treated with antigen-specific peptide. Rabbit Aff - Purified Hu, Ms WB
0.1 ml / €340.00
  Acris Antibodies GmbH

PAK6 pSer602/560 antibody

Western blot analysis of extracts from HeLa cells (Lane 2), using PAK5/6 (Phospho-Ser602/Ser560) Antibody AP55829PU-N. The lane on the left is treated with antigen-specific peptide. Rabbit Aff - Purified Hu, Ms WB
50 µl / €270.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

PAK6 - human gene knockout kit via CRISPR

PAK6 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

PAK6 - human gene knockout kit via CRISPR

PAK6 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

PAK6 - human gene knockout kit via CRISPR

PAK6 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

PAK6 - human gene knockout kit via CRISPR

PAK6 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Pak6 - mouse gene knockout kit via CRISPR

Pak6 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Pak6 - mouse gene knockout kit via CRISPR

Pak6 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Pak6 - mouse gene knockout kit via CRISPR

Pak6 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Pak6 - mouse gene knockout kit via CRISPR

Pak6 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PAK6 (transcript variant 1)

  Purified recombinant kinase domain protein of human p21 protein (Cdc42/Rac)-activated kinase 6 (PAK6), transcript variant 1, 10 µg  
PAK6 Human > 90 %
Preparation: .
Purity Detail: >90% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
10 µg / €139.00
  OriGene Technologies, Inc.

PAK6 (transcript variant 1)

  Purified recombinant kinase domain protein of human p21 protein (Cdc42/Rac)-activated kinase 6 (PAK6), transcript variant 1, 100 µg  
PAK6 Human > 90 %
Preparation: .
Purity Detail: >90% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
0.1 mg / €978.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, PAK6 (mGFP-tagged) - Human p21 protein (Cdc42/Rac)-activated kinase 6 (PAK6), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, PAK6 (mGFP-tagged) - Human p21 protein (Cdc42/Rac)-activated kinase 6 (PAK6), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

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