PAK7 / PAK5 antibody

Principal name

PAK7 / PAK5 antibody

Alternative names for PAK7 / PAK5 antibody

p21-activated kinase 7, PAK-7, p21-activated kinase 5, PAK-5, KIAA1264, Serine/threonine-protein kinase PAK 7

SwissProt ID

Q8C015 (Mouse), Q9P286 (Human)

Gene ID

57144 (PAK7), 241656 (Pak7)

Available reactivities

Hu (Human), Bt (Bat), Bov (Bovine), Can (Canine), Eq (Equine), Mky (Monkey), Por (Porcine), Prim (Primate), Rb (Rabbit), Bear, Ms (Mouse), Rt (Rat)

Available hosts

Rabbit

Available applications

Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), Immunoprecipitation (IP)

Background of PAK7 / PAK5 antibody

The p21-activated kinases (PAKs) are serine-threonine kinases that bind to the active forms of Cdc42 and Rac. They are divided into two groups, the first of which include PAK1, 2 and 3, and can be activated by Cdc42/Rac binding. Group 1 PAKs contain an autoinhibitory domain whose activity is regulated by Cdc42/Rac binding. The group 1 PAKs are known to be involved in cellular processes such as gene transcription, apoptosis, and cell morphology and motility. Much less is known about the second group, which includes PAK4, 5 and 6. These proteins are not activated by Cdc42/Rac binding. PAK5 was initially identified as a kinase expressed primarily in brain that while possessing a kinase domain and GTPase binding domain similar to PAK4 and PAK6, is completely different from both. Expression of PAK5 in neural based cell lines resulted in neurite outgrowth suggesting that PAK5 may be involved in regulating the cytoskeletal changes necessary for promoting neurite outgrowth. Other experiments suggest that unlike the other PAKs, PAK5 may inhibit apoptosis by phosphorylating the Bcl-2 family member Bad.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PAK7 / PAK5 antibody

  Rabbit Polyclonal PAK5 Antibody  
Western blot analysis of PAK5 in T24 lysate with PAK5 antibody at (A) 2 and (B) 4 ug/mL. Rabbit IgG Aff - Purified Hu E, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PAK7 / PAK5 antibody

  Rabbit polyclonal PAK5/6 (Ab-602/560) antibody  
Western blot analysis of extracts from COLO cells, using PAK5/6 (Ab-602/560) antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

PAK7 / PAK5 antibody

  Rabbit polyclonal anti-PAK7 antibody  
Western blot analysis of extracts from rat brain cells, using PAK7 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

PAK7 / PAK5 antibody

  Rabbit polyclonal PAK5/6 (Ser602/Ser560) antibody(Phospho-specific)  
Western blot analysis of extracts from LOVO cells, treated with PMA (125ng/ml, 30mins), using PAK5/6 (Phospho-Ser602/Ser560) antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

PAK7 / PAK5 antibody

  Anti-PAK7 Rabbit Polyclonal Antibody  
Predicted cell location: Cytoplasm. Positive control: Human breast and colon cancer tissue. Recommended dilution: 1/15-50  The image on the left is immunohistochemistry of paraffin-embedded human breast cancer tissue using PAK7 antibody at dilution 1/20, on the right is treated with the fusion protein. (Original magnification:x 200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

PAK7 / PAK5 antibody

  Anti-PAK7 Rabbit Polyclonal Antibody  
Predicted band size: 81 kDa . Positive control: Human fetal kidney tissue lysate. Recommended dilution: 1/200-1000. (Gel: 10%SDS-PAGE Lysate: 40 ug per lane Primary antibody: 1/100dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 3 minutes) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

PAK7 / PAK5 antibody

  Rabbit Polyclonal Anti-PAK7 Antibody (Internal)  
Anti-PAK7 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Hu P
50 µg / €400.00
  OriGene Technologies, Inc.

PAK7 / PAK5 antibody

  Rabbit Polyclonal PAK5 Antibody  
ELISA: PAK5 Antibody Rabbit IgG Purified Hu E
50 µg / €325.00
  OriGene Technologies, Inc.

PAK7 / PAK5 antibody

Immunohistochemistry: AP07334PU-N PAK7 antibody staining of Formalin-Fixed, Paraffin-Embedded Human Brain, Cortex. Rabbit Aff - Purified Hu ICC/IF, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

PAK7 / PAK5 antibody

Formalin-fixed and paraffin-embedded human brain tissue reacted with PAK5 antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Rabbit Ig Purified Hu IP, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

PAK7 / PAK5 (Internal) antibody

Immunohistochemistry: AP20079PU-N PAK7 antibody staining of Formalin-Fixed, Paraffin-Embedded Human Brain, Cortex. Rabbit IgG Aff - Purified Bear, Bov, Bt, Can, Elephant, Eq, Hu, Mky, Por, Prim, Rb E, P
50 µg / €470.00
  Acris Antibodies GmbH

PAK7 / PAK5 pSer602/560 antibody

Western blot analysis of extracts from LOVO cells treated with PMA 125ng/ml 30', using PAK5/6 (Phospho-Ser602/Ser560) Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, WB
50 µg / €230.00
  Assay Biotech

PAK7 / PAK5 pSer602/560 antibody

Western blot analysis of extracts from LOVO cells treated with PMA 125ng/ml 30', using PAK5/6 (Phospho-Ser602/Ser560) Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, WB
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

PAK7 - human gene knockout kit via CRISPR

PAK7 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

PAK7 - human gene knockout kit via CRISPR

PAK7 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

PAK7 - human gene knockout kit via CRISPR

PAK7 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

PAK7 - human gene knockout kit via CRISPR

PAK7 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Pak7 - mouse gene knockout kit via CRISPR

Pak7 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Pak7 - mouse gene knockout kit via CRISPR

Pak7 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Pak7 - mouse gene knockout kit via CRISPR

Pak7 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

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