pan Cytokeratin antibody

Principal name

pan Cytokeratin antibody

Alternative names for pan Cytokeratin antibody

pan Keratin, Cytokeratin pan-reactive

Available reactivities

Amph (Amphibian), Bov (Bovine), Chk (Chicken), Hu (Human), Rt (Rat), Mam (Mammalia), Ms (Mouse), Xen (Xenopus), Can (Canine), Carp, Fe (Feline), GP (Guinea Pig), Gt (Goat), Hst (Hamster), Por (Porcine), Rb (Rabbit), Sh (Sheep), L (Lizard), Macaque, Mky (Monkey), All Species, Dros (Drosophila), Eq (Equine), Fi (Fish), Re (Reptiles)

Available hosts

Mouse, Rabbit, Guinea Pig

Available applications

Frozen Sections (C), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Western blot / Immunoblot (WB), Flow Cytometry (F), Functional assay (FN)

Background of pan Cytokeratin antibody

Cytokeratins, a group comprising at least 29 different proteins, are characteristic of epithelial and trichocytic cells. Cytokeratins 1, 4, 5, 6, and 8 are members of the type II neutral to basic subfamily. Monoclonal anti cytokeratins are specific markers of epithelial cell differentiation and have been widely used as tools in tumor identification and classification. Monoclonal Anti Pan Cytokeratin (mixture) is a broadly reactive reagent, which recognizes epitopes present in most human epithelial tissues. It facilitates typing of normal, metaplastic and neoplastic cells. Synergy between the various components results in staining amplification. This enables identification of cells, which would otherwise be stained only marginally. The mixture may aid in the discrimination of carcinomas and nonepithelial tumors such as sarcomas, lymphomas and neural tumors. It is also useful in detecting micrometastases in lymph nodes, bone marrow and other tissues and for determining the origin of poorly differentiated tumors.
There are two types of cytokeratins the acidic type I cytokeratins and the basic or neutral type II cytokeratins. Cytokeratins are usually found in pairs comprising a type I cytokeratin and a type II cytokeratin. Usually the type II cytokeratins are 8kD larger than their type I counterparts.

General readings

Battifora, H., Sheibani, K., Tubbs, R.R., Kopinski, M.I. and Sun, T.-T.: Anti-keratin antibodies in tumor diagnosis: Distinction between seminoma and embryonal carcinoma. Cancer 54, 843-848 (1984)
Eichner, R., Bonitz, P. and Sun, T.-T.: Classification of epidermal keratins according to their immunoreactivity, isoelectric point and mode of expression. J. Cell. Biol. 98, 1388-1396 (1984)
Garin-Chesa, P., Rettig, J. and Melamed, R.: Expression of cyto- keratin in normal and neoplastic colonic epithelial cells: Implications for cellular differentiation and carcinogenesis. Am. J. Surg. Pathol. 10, 829-835 (1986)
Nelson, W.G., Battifora, H., Santana, H. and Sun, T.-T.: Specific keratins as molecular markers for neoplasms with a stratified epithelial origin. Cancer Res. 44, 1600-1603 (1984)
Nelson, W.G. and Sun, T.-T.: The 50- and 58- kD keratin classes as molecular markers for stratified squamous epithelia: Cell culture studies. J. Cell Biol. 97, 244-251 (1983)
Moll, R., Franke, W.W., Schiller, D.L., Geiger, B. and Krepler, R.: The catalog of human cytokeratins: Patterns of expression in normal epithelia, tumors and cultured cells. Cell 31, 11-24 (1982)
Shi, S.-R., Goodman, M.L., Chan, A.K., Pilch, B.Z., Chen, L.B. and Sun, T.-T.: Immunohistochemical study of nasopharyngeal carcinoma using monoclonal anti-keratin antibodies. Am. J. Pathol. 117, 53-63 (1984)
Spagnolo, D.V., Michie, S.A., Crabtree, G.S., Warnke, R.A. and Rouse, R.V.: Monoclonal anti-keratin (AE1) reactivity in routinely processed tissue from 166 human neoplasms. Am. J. Clin. Pathol. 84, 697-704 (1985)
Sun, T.-T., Eichner, R., Cooper, D., Schermer, A., Nelson, W.G. and Weiss, R.A.: Classification, expression and possible mechanisms of evolution of mammalian epithelial keratins: A unifying model. The Cancer Cell 1, 169-176 (1984)
Sun, T.-T., Eichner, R., A., Nelson, W.G. Tseng, S.C.G., Weiss, R.A., Jarvinen, M. and Woodcock-Mitchell, J.: Keratin classes: Molecular markers for different types of epithelial differentiation. J. Invest. Dermatol. 81, 109-115 (1983)
Sun, T.-T., Tseng, S.C.G., Huang, A.J.W., Cooper, D., Lynch, M.H., Weiss, R.A., Eichner, R., A. and Schermer, A.: Monoclonal antibody studies of keratin expression: A review. In: Intermediate Filaments. The New York Acad. Sci. (E. Wang, D. Fischmann, R. Liem, and T.-T. Sun, eds.) 455, 307-329 (1985)
Tseng, S.C.G., Jarvinen, M., Nelson, W.G., Huang, J.-W., Woodcock-Mitchell, J. and Sun, T.-T.: Correlation of specific keratins with different types of epithelial differentiation: Monoclonal antibody studies. Cell 30, 361-372 (1982)
Woodcock-Mitchell, J., Eichner, R., Nelson, W.G. and Sun, T.-T.: Immunolocalization of keratin polypeptides in human epidermis using monoclonal antibodies. J. Cell Biol. 95, 580-588 (1982)
Weiss, R.A., Eichner, R. and Sun, T.-T.: Monoclonal antibody analyis of keratin expression in epidermal diseases: A 48 kD and a 56 kD keratin as molecular markers for hyperproliferating keratinocytes. J. Cell Biol. 98, 1397-1406 (1984)
Weiss, R.A., Guillet, G.Y., Freedberg, I.M., Small, E.-A., Farmer, E.R., Weiss, M. and Sun, T.-T.: The use of monoclonal antibody to keratin in human epidermal disease: Alterations in immunohistoche- mical staining pattern. J. Invest. Dermatol. 81, 2279-2286 (1983)

  1. Quick-Filters:
  2. Highly Validated (2)

Items 1 to 20 of 33 total

per page
Page:
  1. 1
  2. 2

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

pan Cytokeratin antibody

pan Cytokeratin Guinea Pig Serum Hu, Ms C, ICC/IF, P, WB
0.1 ml / €330.00
  Acris Antibodies GmbH

pan Cytokeratin antibody

Uterus, Human: Formalin-Fixed, Paraffin-Embedded (FFPE) Mouse IgG1 7H8 Ascites Hst, Hu, Sh FN, ICC/IF, P
50 µl / €470.00
  Acris Antibodies GmbH

pan Cytokeratin antibody

BM4068 Cytokeratin antibody staining of Swine Ileum Paraffin Section. Mouse IgG1 Lu5 Aff - Purified Amph, Bov, Chk, Hu, Rt C, P
0.2 mg / €530.00
  Acris Antibodies GmbH

pan Cytokeratin antibody

pan Cytokeratin Mouse IgG1 lu-5 Purified Bov, Chk, Hu, Pleurodeles, Rt, Snake, Xen C, ICC/IF, P
50 µg / €280.00
  Acris Antibodies GmbH

pan Cytokeratin antibody

pan Cytokeratin Mouse IgG1 AE1/AE3 Purified Bov, Chk, Hu, Mky, Ms, Por, Rb, Rt C, ICC/IF, P
1 ml / €380.00
  Acris Antibodies GmbH

pan Cytokeratin antibody

pan Cytokeratin Mouse IgG1 AE1/AE3 Purified Bov, Chk, Hu, Mky, Ms, Por, Rb, Rt C, ICC/IF, P
0.5 ml / €300.00
  Acris Antibodies GmbH

pan Cytokeratin antibody

pan Cytokeratin Mouse IgG1 cocktail Purified Hu C, ICC/IF, P
1 ml / €480.00
  Acris Antibodies GmbH

pan Cytokeratin antibody

pan Cytokeratin Mouse IgG1 cocktail Purified Hu C, ICC/IF, P
0.5 ml / €350.00
  Acris Antibodies GmbH

pan Cytokeratin antibody

pan Cytokeratin Mouse IML-91 Purified Hu, Rt C, P, WB
0.1 mg / €340.00
  Acris Antibodies GmbH

pan Cytokeratin antibody

pan Cytokeratin Mouse IgG1 PC-26 Purified Hu, Rt C, P, WB
0.1 mg / €340.00
  Acris Antibodies GmbH

pan Cytokeratin antibody

pan Cytokeratin Mouse IgG1 80 Supernatant Hu, Ms, Rt C, ICC/IF, P, WB
1 ml / €260.00
  Acris Antibodies GmbH

pan Cytokeratin antibody

pan Cytokeratin Guinea Pig Serum Hu, Ms C, ICC/IF, P, WB
0.1 ml / €370.00
  Acris Antibodies GmbH

pan Cytokeratin (4+5+6+8+10+13+18) antibody

pan Cytokeratin Mouse IgG1 C-11 APC Mam F
0.1 mg / €320.00
  Acris Antibodies GmbH

pan Cytokeratin (4+5+6+8+10+13+18) antibody

pan Cytokeratin Mouse IgG1 C-11 FITC Amph, Bov, Hu, Rt C, F, ICC/IF, P, WB
100 Tests / €610.00
  Acris Antibodies GmbH

pan Cytokeratin (4+5+6+8+10+13+18) antibody

Intracellular Flow Cytometry analysis of cytokeratin expression in HT-29 Human Caucasian colon adenocarcinoma cell line using anti-cytokeratin antibody (C-11) PE. Overlay with Isotype Mouse IgG1 control (PPV-06) Mouse IgG1 C-11 PE Mam F
0.1 mg / €320.00
  Acris Antibodies GmbH

pan Cytokeratin (4+5+6+8+10+13+18) antibody

Figure 2. Detection of cytokeratin on paraffin-embedded sections of guinea pig breast carcinoma using anti-cytokeratin antibody (C-11). Mouse IgG1 C-11 Purified Amph, Mam F, ICC/IF, IP, P, WB
0.1 mg / €210.00
  Acris Antibodies GmbH

pan Cytokeratin antibody

pan Cytokeratin Rabbit Purified Hu, Mam C, P
0.25 ml / €300.00
  Acris Antibodies GmbH

pan Cytokeratin antibody

pan Cytokeratin Mouse cocktail cocktail Supernatant Hu C, P
1 ml / €470.00
  Acris Antibodies GmbH

pan Cytokeratin antibody

pan Cytokeratin Mouse cocktail cocktail Supernatant Hu P
0.5 ml / €320.00
  Acris Antibodies GmbH

pan Cytokeratin antibody

Formalin fixed paraffin embedded human prostate stained with Cytokeratin H.M.W. antibody. DM275 Mouse IgG1 DE-SQ Purified Hu, Rt C, P
1 ml / €460.00
  Acris Antibodies GmbH

Items 1 to 20 of 33 total

per page
Page:
  1. 1
  2. 2
  • LinkedIn