PANK2 antibody

Principal name

PANK2 antibody

Alternative names for PANK2 antibody

Pantothenate kinase 2 mitochondrial, Pantothenic acid kinase 2, C20orf48

SwissProt ID

Q8L5Y9 (Arath), Q9BYW5 (Human), Q9BZ23 (Human)

Gene ID

80025 (PANK2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Can (Canine), Mky (Monkey), Bov (Bovine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit), Sh (Sheep), Ze (Zebrafish)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Flow Cytometry (F), Frozen Sections (C)

Background of PANK2 antibody

Defects in PANK2 are the cause of neurodegeneration with brain iron accumulation type 1 (NBIA1); also known as pantothenate kinase-associated neurodegeneration (PKAN) or Hallervorden-Spatz syndrome (HSS). It is an autosomal recessive neurodegenerative disorder associated with iron accumulation in the brain, primarily in the basal ganglia. Clinical manifestations include progressive muscle spasticity, hyperreflexia, muscle rigidity, dystonia, dysarthria, and intellectual deterioration which progresses to severe dementia over several years. It is clinically classified into classic, atypical, and intermediate phenotypes. Classic forms present with onset in the first decade, rapid progression, loss of independent ambulation within 15 years. Atypical forms have onset in the second decade, slow progression, maintenance of independent ambulation up to 40 years later. Intermediate forms manifest onset in the first decade with slow progression or onset in the second decade with rapid progression. Patients with early onset tend to also develop pigmentary retinopathy, whereas those with later onset tend to also have speech disorders and psychiatric features. All patients have the 'eye of the tiger' sign on brain MRI.Defects in PANK2 are the cause of hypoprebetalipoproteinemia, acanthocytosis, retinitis pigmentosa, and pallidal degeneration (HARP). HARP is a rare syndrome with many clinical similarities to NBIA1.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PANK2 antibody

Immunohistochemical staining of paraffin-embedded Carcinoma of Human prostate tissue using anti-PANK2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA501321, Dilution 1:50) Mouse IgG2a OTI3H9 Purified Can, Hu, Mky, Rt F, ICC/IF, P, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

PANK2 antibody

Immunohistochemical staining of paraffin-embedded Human prostate tissue within the normal limits using anti-PANK2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA501355, Dilution 1:50) Mouse IgG2a OTI4B3 Purified Hu ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

PANK2 antibody

Host: Rabbit; Target Name: PANK2; Sample Tissue: COLO205 Whole Cell lysates; Antibody Dilution: 1.0 ug/ml PANK2 is supported by BioGPS gene expression data to be expressed in COLO205 Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Sh, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

PANK2 antibody

Host: Rabbit; Target Name: PANK2; Sample Tissue: HepG2 Whole cell lysates; Antibody Dilution: 1.0 ug/ml PANK2 is supported by BioGPS gene expression data to be expressed in HepG2 Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Sh, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

PANK2 antibody

Anti-PANK2 mouse monoclonal antibody (TA501419) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PANK2(RC215676). Mouse IgG1 OTI3G4 Purified Hu F, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

PANK2 (N-term) antibody

Western blot analysis of anti-PANK2 Pab in mouse liver tissue lysate (35ug/lane). PANK2(arrow) was detected using the purified Pab (1:60 dilution). Rabbit Ig Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

PANK2 (Center) antibody

Western blot analysis of anti-PANK2 Pab in mouse liver tissue lysate (35ug/lane). PANK2(arrow) was detected using the purified Pab (1:40 dilution). Rabbit Ig Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

PANK2 antibody

Immunoperoxidase of monoclonal antibody to PANK2 on formalin-fixed paraffin-embedded human endometrium tissue. [antibody concentration sup. ug/ml] Mouse IgG2a 2B12 Purified Hu E, P, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

PANK2 antibody

Western blot analysis of PANK2 polyclonal antibody ( Cat # PAB2719 ) in mouse liver tissue lysate ( 35 µg/lane ) . PANK2 ( arrow ) was detected using the purified polyclonal abtibody ( 1 : 60 dilution ) . Rabbit Hu E, WB
0.4 ml / €390.00
  Abnova Taiwan Corp.

PANK2 antibody

PANK2 Rabbit Hu E, WB
0.4 ml / €390.00
  Abnova Taiwan Corp.

PANK2 antibody

PANK2 Rabbit Hu, Ms E, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

PANK2 antibody

Western blot analysis of PANK2 expression in HepG2 (A); MCF7 (B); HT29 (C); mouse liver (D); PC12 (E) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rt WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

PANK2 antibody

Western blot analysis of PANK2 expression in HepG2 (A); MCF7 (B); HT29 (C); mouse liver (D); PC12 (E) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rt WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

PANK2 antibody

Western blot analysis of PANK2 expression in HepG2 (A); MCF7 (B); HT29 (C); mouse liver (D); PC12 (E) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rt WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PANK2 (transcript variant 1)

PANK2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

PANK2 overexpression lysate

PANK2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

PANK2 overexpression lysate

PANK2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

17 Item(s)

per page
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