PANX2 antibody

Principal name

PANX2 antibody

Alternative names for PANX2 antibody

Pannexin-2, Pannexin 2, PX2, MGC119432

SwissProt ID

P60571 (Rat), Q6IMP4 (Mouse), Q96RD6 (Human)

Gene ID

56666 (PANX2), 362979 (Panx2)

Available reactivities

Can (Canine), Chk (Chicken), Hu (Human), Ms (Mouse), Rt (Rat), Ze (Zebrafish)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), Frozen Sections (C)

Background of PANX2 antibody

Gap junctions are usually found in clusters and eble intercellular communication by allowing the passage of small molecules between cells. They play important roles in different biological processes. These include differentiation, cell cycle synchronization, cellular development, neurol activity and the immune response. Proteins involved in gap junction formation are composed of four transmembrane domains, 2 extracellular loops and one intracellular loop and intracellular N- and C-termini. Several consensus cysteine residues are in the extracellular loop and are essential and necessary for intercellular docking of gap junction hemichannels in the opposing cell membrane. Pannexins (Pannexin 1, Pannexin 2 and Pannexin 3) belong to the superfamily of gap junction proteins. Pannexin 1 (PANX1) is ubiquitously expressed, Pannexin 2 (PANX2) is specifically expressed in the human brain and widespread in rodents and Pannexin 3 (PANX3) is also detected in the brain. The gating properties of Pannexins were studied in Xenopus oocytes and results demonstrate that only PANX1 is able to form homomeric hemichannels, and is also able to form heteromeric hemichannels with PANX2 but not with PANX3. Not surprising, PANX1 gating properties depend whether it forms homomeric or heteromeric hemichannels. A number of different stimuli are known to open these channels and include mechanical stress, extracellular ATP, increases in intracellular Ca2+ and inflammation. Possible roles for Pannexins include paracrine sigling in vascular endothelial cells and taste cell sigling.

General readings

Baranova,A., (2004) Genomics 83 (4), 706-716

16 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PANX2 antibody

PANX2 Mouse IgG1 S121A-31 Purified Rt P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PANX2 antibody

Western blot analysis of rat (lanes 1 and 3) and mouse (lanes 2 and 4) brain lysates: 1, 2. Anti-Pannexin 2 (extracellular) antibody , (1:200). 3, 4. Anti-Pannexin 2 (extracellular) antibody, preincubated with the control peptide antigen. Rabbit Purified Hu, Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

PANX2 antibody

Adult rat hippocampus immunohistochemistry Mouse IgG2a N121A/1 Supernatant Rt C, WB
5 ml / €320.00
  Antibodies Incorporated

NeuroMab

PANX2 antibody

Adult rat hippocampus immunohistochemistry Mouse IgG1 N121A/31 Supernatant Rt C, WB
5 ml / €320.00
  Antibodies Incorporated

NeuroMab

PANX2 antibody

Adult rat hippocampus immunohistochemistry Mouse IgG2a N121A/1 Purified Rt C, WB
0.1 ml / €380.00
  Antibodies Incorporated

NeuroMab

PANX2 antibody

Adult rat hippocampus immunohistochemistry Mouse IgG1 N121A/31 Purified Rt C, WB
0.1 ml / €380.00
  Antibodies Incorporated

NeuroMab

PANX2 antibody

PANX2 Mouse IgG1 2B11 Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

PANX2 antibody

Human Muscle; PANX2 antibody - N-terminal region (ARP42778_T100) in Human Muscle cells using Immunohistochemistry Rabbit Aff - Purified Can, Chk, Hu, Ms, Rt, Ze P, WB
0.1 mg / €310.00
  AVIVA Systems Biology

PANX2 antibody

Western Blot: pannexin 2 Antibody [NBP1-59671] - This Anti-PANX2 antibody was used in Western Blot of HepG2 tissue lysate at a concentration of 1.25ug/ml. Rabbit Purified Can, Hu, Ms, Rt, Ze P, WB
0.1 mg / €360.00
  Novus Biologicals Inc.

PANX2 antibody

Immunohistochemistry-Paraffin: Pannexin 2 Antibody [NBP1-92242] - Immunohistochemical staining of human adrenal gland shows strong cytoplasmic positivity in cortical cells. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Western Blot/IP/ChiP Kits

Catalog No. Host Iso. Clone Pres. React. Applications  

PANX2 Western Blot Kit

PANX2 Western Blot Kit Hu
25 Western Blots / kit / €640.00
  AVIVA Systems Biology

PANX2 Western Blot kit

PANX2 Western Blot kit
1 kit / €640.00
  AVIVA Systems Biology

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PANX2

PANX2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

PANX2

PANX2 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

PANX2

PANX2 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

PANX2 overexpression lysate

PANX2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

16 Item(s)

per page
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