PAQR8 antibody

Principal name

PAQR8 antibody

Alternative names for PAQR8 antibody

mPR beta, Membrane progestin receptor beta, C6orf33, LMPB1, MPRB, Progestin and adipoQ receptor family member VIII, Lysosomal membrane protein in brain-1, chromosome 6 open reading frame 33

SwissProt ID

Q80ZE5 (Mouse), Q865K9 (Pig), Q8TEZ7 (Human)

Gene ID

85315 (PAQR8), 74229 (Paqr8)

Available reactivities

Hu (Human), Ms (Mouse), Por (Porcine), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Rb (Rabbit)

Available hosts


Available applications

Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Flow Cytometry (F), Paraffin Sections (P)

Background of PAQR8 antibody

The steroid progesterone induces the resumption of maturation in oocytes via a nongenomic pathway through binding to a novel membrane progestin receptor (mPR). This pathway inhibits adenylyl cyclase and reduces intracellular cAMP, and also activates mitogen-activated protein kinase to effect signal transduction pathways. Five distinct groups, designated Alpha, Beta, Gamma, Delta, comprise the mPR gene family. mPR Alpha, also designated progestin and adipo Theta receptor family member VII (PAQR7), consists of an extracellular N-terminus, an intracellular C-terminus and seven transmembrane domains. mPR Alpha is expressed in ovary, testis, placenta, uterus and bladder. mPR Beta, or progestin and adipo Theta receptor family member VIII (PAQR8), consists of eight putative transmembrane regions and an intracellular N-terminus that contains a leucine-rich motif. mPR Beta is a 354 amino acid protein expressed in brain and spinal cord. Both mPR Alpha and mPR Beta may be G protein-coupled receptors and may be involved in oocyte maturation.

General readings

Smith, J.L., et al. Steroids 73(11):1160-1173(2008)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Tang, Y.T., et al. J. Mol. Evol. 61(3):372-380(2005)
Mungall, A.J., et al. Nature 425(6960):805-811(2003)
Hammes, S.R. Proc. Natl. Acad. Sci. U.S.A. 100(5):2168-2170(2003)

7 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PAQR8 antibody

PAQR8 Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

PAQR8 (C-term) antibody

PAQR8 Rabbit Ig Aff - Purified Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

PAQR8 antibody

PAQR8 Rabbit Hu, Ms, Rt E, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

PAQR8 antibody

PAQR8 Rabbit Ms E, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

PAQR8 antibody

PAQR8 Rabbit Serum Hu, Ms, Por, Rt ICC/IF, WB
0.1 ml / €400.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  


PAQR8 Human
2 µg / €450.00
  Abnova Taiwan Corp.


PAQR8 Human in vitro transl.
2 µg / €300.00
  Abnova Taiwan Corp.

7 Item(s)

per page
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