PARL antibody

Principal name

PARL antibody

Alternative names for PARL antibody

PSARL, PRO2207, Presenilins-associated rhomboid-like protein mitochondrial, Mitochondrial intramembrane cleaving protease PARL

SwissProt ID

Q2KHV4 (Bovin), Q3B8P0 (Rat), Q58EK4 (Danre), Q5XJY4 (Mouse), Q9H300 (Human)

Gene ID

55486 (PARL)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Ms (Mouse), Rt (Rat), Chk (Chicken), Mky (Monkey), Eq (Equine), Por (Porcine), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of PARL antibody

PARL is a mitochondrial integral membrane protein and a member of the highly conserved rhomboid superfamily of membrane proteins. PARL is required for the control of apoptosis during postnatal growth and is required for the processing of OPA1, a protein that prevents the release of cytochrome C from the mitochondria in response to apoptotic signals. In lymphocytes and neurons, PARL's association with other proteins, such as the Bcl-2 family-related protein Hax1 and Omi can lead to the proteolytic processing of Omi by PARL, preventing the accumulation of Bax, thereby suppressing apoptosis. Variations in this gene have been associated with increased risk for type 2 diabetes. PARL may also play a role in the progression of Alzheimer's disease through its associations with presenilin-1 and -2. Despite its predicted molecular weight of ~42kDa, PARL is observed at a higher molecular weight in SDS-PAGE. Multiple isoforms of PARL are known to exist.

General readings

Walder,K., (2005) Diabetologia 48 (3), 459-468

16 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PARL antibody

Western blot analysis of PARL in 3T3 cell lysate with PARL antibody at (A) 1 and (B) 2 ug/mL. Rabbit IgG Aff - Purified Hu, Ms, Rt E, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PARL antibody

WB Suggested Anti-PARL Antibody Titration: 0.5 ug/ml; Positive Control: Jurkat cell lysate;PARL is supported by BioGPS gene expression data to be expressed in Jurkat Rabbit IgG Purified Can, Eq, Hu, Ms, Por, Rb, Rt P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

PARL antibody

Western blot analysis using PARL antibody Cat.-No AM06254SU-N against truncated Trx-PARL recombinant protein (Lane 1) and truncated MBP-PARL(aa112-167) recombinant protein (Lane 2). Mouse IgG2b 8C4B2 Ascites Hu E, WB
0.1 ml / €360.00
  Acris Antibodies GmbH

PARL (N-term) antibody

Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit IgG Purified Hu, Ms, Rt P, WB
50 µg / €470.00
  Acris Antibodies GmbH

PARL Control Peptide

PARL
50 µg / €160.00
  Acris Antibodies GmbH

PARL antibody

PARL Mouse IgG2b 4F4 Purified Hu E
0.1 mg / €370.00
  Abnova Taiwan Corp.

PARL antibody

Western blot analysis of PARL in NIH/3T3 cell lysate with PARL polyclonal antibody ( Cat # PAB13061 ) at ( A ) 1 and ( B ) 2 µg/ml. Rabbit Hu, Ms, Rt WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

PARL antibody

Human kidney; PARL antibody - N-terminal region (ARP44851_P050) in Human kidney cells using Immunohistochemistry Rabbit Aff - Purified Bov, Can, Hu, Ms, Rt P, WB
50 µg / €350.00
  AVIVA Systems Biology

PARL antibody

PARL Rabbit Aff - Purified Chk, Hu, Mky, Ms, Rt E, WB
0.1 mg / €320.00
  Novus Biologicals Inc.

PARL antibody

PARL Mouse IgG2b 8C4B2;1H12E10 Purified Hu E, WB
0.1 ml / €380.00
  Novus Biologicals Inc.

PARL antibody

Western Blot: PARL Antibody [NBP1-59496] - This Anti-PARL antibody was used in Western Blot of Jurkat tissue lysate at a concentration of 0.5ug/ml. Rabbit Aff - Purified Bov, Can, Hu, Ms, Rt P, WB
50 µg / €440.00
  Novus Biologicals Inc.

PARL antibody

Immunocytochemistry: PARL Antibody [NBP1-76938] - Immunocytochemistry of PARL in 3T3 cells with PARL antibody at 2.5 µg/ml. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

PARL antibody

Immunohistochemistry-Paraffin: PARL Antibody [NBP1-80878] - Immunohistochemistry-Paraffin: PARL Antibody [NBP1-80878] Immunohistochemical staining of human duodenum shows moderate cytoplasmic positivity in glandular cells. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PARL

PARL Human Purified
2 µg / €300.00
  Abnova Taiwan Corp.

PARL

PARL Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

PARL

PARL Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

16 Item(s)

per page
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