PARN antibody

Principal name

PARN antibody

Alternative names for PARN antibody

Polyadenylate-specific ribonuclease, Deadenylating nuclease, Deadenylation nuclease, DAN, Poly(A)-specific ribonuclease PARN

SwissProt ID

O95453 (Human), P69341 (Bovin), Q7ZU92 (Danre), Q8VDG3 (Mouse), Q90ZA1 (Xenla), Q9LG26 (Arath)

Gene ID

5073 (PARN), 74108 (Parn)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Ze (Zebrafish), African clawed frog, Xen (Xenopus)

Available hosts

Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Paraffin Sections (P), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of PARN antibody

The protein encoded by this gene is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mRNAs. Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs. This protein is also involved in silencing of certain maternal mRNAs during oocyte maturation and early embryonic development, as well as in nonsense-mediated decay (NMD) of mRNAs that contain premature stop codons. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]. Transcript Variant: This variant (1) encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

Katayama,S., et al., (2005) Science 309 (5740), 1564-1566

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PARN antibody

Immunohistochemical staining of paraffin-embedded Human prostate tissue using anti-PARN mouse monoclonal antibody. (UM800040; heat-induced epitope retrieval by 10mM citric buffer, pH9.0, 120C for 3min) Mouse IgG2a UMAB143 Purified Hu P, WB
0.1 ml / €468.00
  OriGene Technologies, Inc.

UltraMAB

PARN antibody

Immunohistochemical staining of paraffin-embedded Human prostate tissue using anti-PARN mouse monoclonal antibody. (UM800040; heat-induced epitope retrieval by 10mM citric buffer, pH9.0, 120C for 3min) Mouse IgG2a UMAB143 Purified Hu P, WB
30 µl / €140.00
  OriGene Technologies, Inc.

UltraMAB

PARN antibody

Immunohistochemical staining of paraffin-embedded Human lymphoma tissue using anti-PARN mouse monoclonal antibody. (TA802649) Dilution: 1:150 Mouse IgG2a OTIG5 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

PARN antibody

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-PARN mouse monoclonal antibody. (TA802650) Dilution: 1:150 Mouse IgG2a OTIE12 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

PARN antibody

Immunohistochemical staining of paraffin-embedded Human tonsil within the normal limits using anti-PARN mouse monoclonal antibody. (TA802653) Dilution: 1:150 Mouse IgG2a OTIC9 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

PARN antibody

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-PARN mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA802668) Mouse IgG2a OTI4D12 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

PARN antibody

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-PARN mouse monoclonal antibody. (TA802720) Dilution: 1:150 Mouse IgG2b OTIG7 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

PARN antibody

Immunofluorescence of purified MaxPab antibody to PARN on HeLa cell. [antibody concentration 10 ug/ml] Mouse Purified Hu, Ms, Rt E(detection), ICC/IF, WB
50 µg / €370.00
  Abnova Taiwan Corp.

PARN antibody

WB Suggested Anti-PARN Antibody Titration: 1.25ug/ml; ELISA Titer: 1:312500; Positive Control: SP2/0 cell lysate Rabbit IgG Purified Hu, Ms WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PARN antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PARN (RC207220, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PARN. Mouse IgG2b OTID6 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

PARN antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PARN (RC207220, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PARN. Mouse IgG1 OTID3 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

PARN antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PARN (RC207220, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PARN. Mouse IgG1 OTIG9 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

PARN antibody

Immunohistochemical staining of paraffin-embedded Human tonsil within the normal limits using anti-PARN mouse monoclonal antibody. (TA802721) Dilution: 1:150 Mouse IgG2b OTID9 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

PARN antibody

PARN polyclonal antibody (A01), Lot # 051019JC01. Western Blot analysis of PARN expression in human ovary cancer. Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

PARN antibody

Human HEK-293; . Lanes: Lane 1: 7ug HEK293 cytoplasmic lysate . 2: 7ug HEK293 nuclei lysate. Primary Antibody Dilution: 1:500. Secondary Antibody: Anti-rabbit-HRP. Secondary Antibody Dilution: 1:500. Gene Name: PARN. Submitted by: Seiji Masuda, Kitashirakawa Oiwakecho, Kyoto University.; PARN antibody - N-terminal region (ARP37393_T100) in Human HEK-293 cells using Western Blot Rabbit IgG Purified African clawed frog, Bov, Can, Hu, Ms, Rt, Ze WB
0.1 mg / €310.00
  AVIVA Systems Biology

PARN antibody

PARN Rabbit Purified Bov, Can, Hu, Ms, Rt, Xen, Ze WB
0.1 mg / €360.00
  Novus Biologicals Inc.

PARN antibody

Immunohistochemistry-Paraffin: PARN Antibody [NBP1-84302] - Immunohistochemical staining of human stomach shows strong nuclear and cytoplasmic positivity in glandular cells. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

PARN antibody

Immunohistochemistry-Paraffin: PARN Antibody [NBP1-84303] - Immunohistochemical staining of human stomach shows strong nuclear positivity in glandular cells. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PARN (transcript variant 1)

PARN Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

PARN

PARN Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

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